Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CNR1 3件: Rap1 signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling D00306 Dronabinol 8件: 2, 8, 13, 36, 46, 96, 271, 298
2 CNR1 3件: Rap1 signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling D05099 Nabilone 2件: 6, 13
3 CNR1 3件: Rap1 signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling D05731 Rimonabant 1件: 193
4 CNR1 3件: Rap1 signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling D10915 Cannabidiol 19件: 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
5 ADORA2A 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D00045 Adenosine 3件: 13, 58, 65
6 ADORA2A 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D00528 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
7 ADORA2A 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D01453 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
8 ADORA2A 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D02017 Theophylline 2件: 236, 299
9 ADORA2A 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D02769 Adenosine phosphate 1件: 46
10 ADORA2A 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D04641 Istradefylline 1件: 6
11 ADORA2A 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D05711 Regadenoson 1件: 58
12 ADORA2A 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D09717 Preladenant 1件: 6
13 ADORA2A 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D10174 Tozadenant 1件: 6
14 ADORA2B 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D00045 Adenosine 3件: 13, 58, 65
15 ADORA2B 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D00227 Aminophylline 1件: 63
16 ADORA2B 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D00371 Theophylline 2件: 236, 299
17 ADORA2B 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D01712 Theophylline 2件: 236, 299
18 ADORA2B 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D02769 Adenosine phosphate 1件: 46
19 ADORA2B 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D05429 Aminophylline 1件: 63
20 ADORA2B 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D06103 Theophylline 2件: 236, 299
21 ADORA2B 2件: Rap1 signaling pathway, Vascular smooth muscle contraction D06104 Theophylline 2件: 236, 299
22 MAPK14 18件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
23 MAPK14 18件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8
24 CSF1 5件: Ras signaling pathway, Rap1 signaling pathway, Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, Rheumatoid arthritis D06402 Sunitinib 2件: 28, 34
25 CSF1 5件: Ras signaling pathway, Rap1 signaling pathway, Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, Rheumatoid arthritis D08552 Sunitinib 2件: 28, 34
26 CSF1R 4件: Ras signaling pathway, Rap1 signaling pathway, Viral protein interaction with cytokine and cytokine receptor, Transcriptional misregulation in cancer D11270 Pexidartinib 1件: 34
27 DRD2 1件: Rap1 signaling pathway D00059 Levodopa 8件: 2, 4, 6, 17, 90, 140, 164, 201
28 DRD2 1件: Rap1 signaling pathway D00136 Haloperidol 1件: 8
29 DRD2 1件: Rap1 signaling pathway D00270 Chlorpromazine 1件: 254
30 DRD2 1件: Rap1 signaling pathway D00426 Risperidone 5件: 8, 156, 179, 187, 206
31 DRD2 1件: Rap1 signaling pathway D00454 Olanzapine 2件: 2, 8
32 DRD2 1件: Rap1 signaling pathway D00458 Quetiapine 2件: 6, 13
33 DRD2 1件: Rap1 signaling pathway D00502 Pergolide 1件: 6
34 DRD2 1件: Rap1 signaling pathway D00559 Pramipexole 3件: 2, 6, 20
35 DRD2 1件: Rap1 signaling pathway D00560 Pimozide 1件: 2
36 DRD2 1件: Rap1 signaling pathway D00633 Dopamine 4件: 6, 7, 74, 299
37 DRD2 1件: Rap1 signaling pathway D00702 Buspirone 3件: 6, 51, 179
38 DRD2 1件: Rap1 signaling pathway D00726 Metoclopramide 1件: 51
39 DRD2 1件: Rap1 signaling pathway D00780 Bromocriptine 2件: 6, 74
40 DRD2 1件: Rap1 signaling pathway D00784 Ropinirole 4件: 2, 6, 74, 309
41 DRD2 1件: Rap1 signaling pathway D00789 Chlorpromazine 1件: 254
42 DRD2 1件: Rap1 signaling pathway D00799 Trifluoperazine 2件: 283, 284
43 DRD2 1件: Rap1 signaling pathway D00987 Cabergoline 3件: 6, 74, 75
44 DRD2 1件: Rap1 signaling pathway D01044 Flupentixol 1件: 97
45 DRD2 1件: Rap1 signaling pathway D01164 Aripiprazole 2件: 6, 206
46 DRD2 1件: Rap1 signaling pathway D01226 Sulpiride 5件: 2, 6, 17, 46, 70
47 DRD2 1件: Rap1 signaling pathway D01348 Terguride 2件: 51, 86
48 DRD2 1件: Rap1 signaling pathway D01448 Trifluoperazine 2件: 283, 284
49 DRD2 1件: Rap1 signaling pathway D01462 Lisuride 2件: 6, 86
50 DRD2 1件: Rap1 signaling pathway D01745 Domperidone 5件: 6, 13, 17, 51, 230
51 DRD2 1件: Rap1 signaling pathway D01898 Haloperidol 1件: 8
52 DRD2 1件: Rap1 signaling pathway D02004 Apomorphine 3件: 5, 6, 7
53 DRD2 1件: Rap1 signaling pathway D02213 Metoclopramide 1件: 51
54 DRD2 1件: Rap1 signaling pathway D03165 Bromocriptine 2件: 6, 74
55 DRD2 1件: Rap1 signaling pathway D03274 Chlorpromazine 1件: 254
56 DRD2 1件: Rap1 signaling pathway D04034 Chlorpromazine 1件: 254
57 DRD2 1件: Rap1 signaling pathway D05008 Metoclopramide 1件: 51
58 DRD2 1件: Rap1 signaling pathway D05575 Pramipexole 3件: 2, 6, 20
59 DRD2 1件: Rap1 signaling pathway D05768 Rotigotine 2件: 6, 127
60 DRD2 1件: Rap1 signaling pathway D06623 Olanzapine 2件: 2, 8
61 DRD2 1件: Rap1 signaling pathway D07305 Piribedil 1件: 6
62 DRD2 1件: Rap1 signaling pathway D07309 Melperone 1件: 6
63 DRD2 1件: Rap1 signaling pathway D07460 Apomorphine 3件: 5, 6, 7
64 DRD2 1件: Rap1 signaling pathway D07593 Buspirone 3件: 6, 51, 179
65 DRD2 1件: Rap1 signaling pathway D07868 Domperidone 5件: 6, 13, 17, 51, 230
66 DRD2 1件: Rap1 signaling pathway D07870 Dopamine 4件: 6, 7, 74, 299
67 DRD2 1件: Rap1 signaling pathway D08132 Lisuride 2件: 6, 86
68 DRD2 1件: Rap1 signaling pathway D08339 Pergolide 1件: 6
69 DRD2 1件: Rap1 signaling pathway D08456 Quetiapine 2件: 6, 13
70 DRD2 1件: Rap1 signaling pathway D08489 Ropinirole 4件: 2, 6, 74, 309
71 DRD2 1件: Rap1 signaling pathway D08549 Sulpiride 5件: 2, 6, 17, 46, 70
72 DRD2 1件: Rap1 signaling pathway D08590 Tiapride 1件: 8
73 DRD2 1件: Rap1 signaling pathway D08636 Trifluoperazine 2件: 283, 284
74 DRD2 1件: Rap1 signaling pathway D09397 Pardoprunox 1件: 6
75 DRD2 1件: Rap1 signaling pathway D09886 Dexpramipexole 1件: 2
76 DRD2 1件: Rap1 signaling pathway D09953 Pridopidine 3件: 2, 6, 8
77 DRD2 1件: Rap1 signaling pathway D09997 Cariprazine 1件: 21
78 DRD2 1件: Rap1 signaling pathway D11839 Foslevodopa 1件: 6
79 EGFR 5件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D01977 Gefitinib 1件: 75
80 EGFR 5件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D03455 Cetuximab 5件: 34, 51, 86, 89, 331
81 EGFR 5件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D04023 Erlotinib 1件: 94
82 EGFR 5件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D04024 Lapatinib 3件: 34, 74, 75
83 EGFR 5件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D07907 Erlotinib 1件: 94
84 EGFR 5件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D08108 Lapatinib 3件: 34, 74, 75
85 EGFR 5件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D11251 Icotinib 1件: 34
86 EGFR 5件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D11772 Tesevatinib 1件: 67
87 EPHA2 2件: Ras signaling pathway, Rap1 signaling pathway D03658 Dasatinib 2件: 51, 85
88 EPHA2 2件: Ras signaling pathway, Rap1 signaling pathway D06414 Dasatinib 2件: 51, 85
89 FGFR1 5件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
90 FGFR1 5件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton D11589 Infigratinib 1件: 276
91 FGFR3 4件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
92 FGFR3 4件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D11589 Infigratinib 1件: 276
93 FGFR2 4件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D05338 Palifermin 5件: 13, 36, 38, 39, 65
94 FGFR2 4件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
95 FGFR2 4件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D11589 Infigratinib 1件: 276
96 FLT1 4件: Ras signaling pathway, Rap1 signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D03218 Axitinib 1件: 34
97 FLT1 4件: Ras signaling pathway, Rap1 signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D06402 Sunitinib 2件: 28, 34
98 FLT1 4件: Ras signaling pathway, Rap1 signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D08552 Sunitinib 2件: 28, 34
99 FLT1 4件: Ras signaling pathway, Rap1 signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D08881 Cediranib 1件: 34
100 FLT1 4件: Ras signaling pathway, Rap1 signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D10481 Nintedanib 5件: 51, 85, 89, 227, 228
101 FLT4 2件: Ras signaling pathway, Rap1 signaling pathway D03218 Axitinib 1件: 34
102 FLT4 2件: Ras signaling pathway, Rap1 signaling pathway D06272 Sorafenib 2件: 34, 86
103 FLT4 2件: Ras signaling pathway, Rap1 signaling pathway D06402 Sunitinib 2件: 28, 34
104 FLT4 2件: Ras signaling pathway, Rap1 signaling pathway D08524 Sorafenib 2件: 34, 86
105 FLT4 2件: Ras signaling pathway, Rap1 signaling pathway D08552 Sunitinib 2件: 28, 34
106 FLT4 2件: Ras signaling pathway, Rap1 signaling pathway D08881 Cediranib 1件: 34
107 FLT4 2件: Ras signaling pathway, Rap1 signaling pathway D10481 Nintedanib 5件: 51, 85, 89, 227, 228
108 FLT4 2件: Ras signaling pathway, Rap1 signaling pathway D11772 Tesevatinib 1件: 67
109 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D00711 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
110 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
111 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D00777 Amantadine 4件: 6, 8, 13, 127
112 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D00848 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
113 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D02780 Acamprosate 2件: 6, 206
114 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
115 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D03744 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
116 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D04905 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
117 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D07058 Acamprosate 2件: 6, 206
118 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D07283 Esketamine 3件: 2, 4, 70
119 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D07441 Amantadine 4件: 6, 8, 13, 127
120 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
121 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D08174 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
122 GRIN1 3件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia D09917 Latrepirdine 1件: 8
123 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00711 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
124 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
125 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00777 Amantadine 4件: 6, 8, 13, 127
126 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00848 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
127 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D02780 Acamprosate 2件: 6, 206
128 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
129 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03744 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
130 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D04905 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
131 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07058 Acamprosate 2件: 6, 206
132 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07283 Esketamine 3件: 2, 4, 70
133 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07441 Amantadine 4件: 6, 8, 13, 127
134 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
135 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08174 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
136 GRIN2A 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D09917 Latrepirdine 1件: 8
137 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00711 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
138 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
139 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00777 Amantadine 4件: 6, 8, 13, 127
140 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00848 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
141 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D02780 Acamprosate 2件: 6, 206
142 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
143 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03744 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
144 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D04905 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
145 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07058 Acamprosate 2件: 6, 206
146 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07283 Esketamine 3件: 2, 4, 70
147 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07441 Amantadine 4件: 6, 8, 13, 127
148 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
149 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08174 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
150 GRIN2B 4件: Ras signaling pathway, Rap1 signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D09917 Latrepirdine 1件: 8
151 IGF1R 4件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
152 IGF1R 4件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D04870 Mecasermin 6件: 65, 78, 96, 168, 265, 299
153 IGF1R 4件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D09680 Teprotumumab 1件: 51
154 IGF1R 4件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D09925 Linsitinib 1件: 232
155 INSR 4件: Ras signaling pathway, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D00085 Insulin human 2件: 96, 156
156 INSR 4件: Ras signaling pathway, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D03230 Insulin human 2件: 96, 156
157 INSR 4件: Ras signaling pathway, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D03250 Insulin glargine 1件: 299
158 INSR 4件: Ras signaling pathway, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D04539 Insulin detemir 1件: 299
159 ITGAL 5件: Rap1 signaling pathway, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Rheumatoid arthritis, Viral myocarditis D03959 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96
160 KDR 3件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway D03218 Axitinib 1件: 34
161 KDR 3件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway D06272 Sorafenib 2件: 34, 86
162 KDR 3件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway D06402 Sunitinib 2件: 28, 34
163 KDR 3件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway D08524 Sorafenib 2件: 34, 86
164 KDR 3件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway D08552 Sunitinib 2件: 28, 34
165 KDR 3件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway D08881 Cediranib 1件: 34
166 KDR 3件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway D10062 Cabozantinib 1件: 34
167 KDR 3件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway D10481 Nintedanib 5件: 51, 85, 89, 227, 228
168 KDR 3件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway D11772 Tesevatinib 1件: 67
169 KIT 2件: Ras signaling pathway, Rap1 signaling pathway D01441 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
170 KIT 2件: Ras signaling pathway, Rap1 signaling pathway D03658 Dasatinib 2件: 51, 85
171 KIT 2件: Ras signaling pathway, Rap1 signaling pathway D06272 Sorafenib 2件: 34, 86
172 KIT 2件: Ras signaling pathway, Rap1 signaling pathway D06402 Sunitinib 2件: 28, 34
173 KIT 2件: Ras signaling pathway, Rap1 signaling pathway D06414 Dasatinib 2件: 51, 85
174 KIT 2件: Ras signaling pathway, Rap1 signaling pathway D08066 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
175 KIT 2件: Ras signaling pathway, Rap1 signaling pathway D08524 Sorafenib 2件: 34, 86
176 KIT 2件: Ras signaling pathway, Rap1 signaling pathway D08552 Sunitinib 2件: 28, 34
177 KIT 2件: Ras signaling pathway, Rap1 signaling pathway D08953 Nilotinib 5件: 6, 8, 34, 51, 86
178 KIT 2件: Ras signaling pathway, Rap1 signaling pathway D10229 Masitinib 6件: 2, 5, 6, 13, 46, 96
179 KIT 2件: Ras signaling pathway, Rap1 signaling pathway D11270 Pexidartinib 1件: 34
180 MET 4件: Ras signaling pathway, Rap1 signaling pathway, Transcriptional misregulation in cancer, Renal cell carcinoma D10062 Cabozantinib 1件: 34
181 NGF 2件: Ras signaling pathway, Rap1 signaling pathway D09387 Tanezumab 2件: 226, 298
182 NGFR 3件: Ras signaling pathway, Rap1 signaling pathway, Transcriptional misregulation in cancer D11028 Cenegermin 2件: 53, 90
183 PDGFRA 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D01441 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
184 PDGFRA 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D06402 Sunitinib 2件: 28, 34
185 PDGFRA 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D08066 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
186 PDGFRA 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D08552 Sunitinib 2件: 28, 34
187 PDGFRA 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D08953 Nilotinib 5件: 6, 8, 34, 51, 86
188 PDGFRA 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
189 PDGFRB 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D03658 Dasatinib 2件: 51, 85
190 PDGFRB 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D06272 Sorafenib 2件: 34, 86
191 PDGFRB 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D06402 Sunitinib 2件: 28, 34
192 PDGFRB 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D06414 Dasatinib 2件: 51, 85
193 PDGFRB 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D08524 Sorafenib 2件: 34, 86
194 PDGFRB 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D08552 Sunitinib 2件: 28, 34
195 PDGFRB 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D08953 Nilotinib 5件: 6, 8, 34, 51, 86
196 PDGFRB 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
197 PGF 2件: Ras signaling pathway, Rap1 signaling pathway D09574 Aflibercept 2件: 90, 166
198 PIK3CA 20件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
199 PIK3CB 20件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
200 PIK3CD 20件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
201 PIK3CD 20件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11437 Parsaclisib 3件: 35, 53, 61
202 MAPK11 18件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
203 MAPK11 18件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8
204 MAPK13 18件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
205 MAPK13 18件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8
206 MAP2K1 17件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib 1件: 34
207 MAP2K1 17件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
208 MAP2K1 17件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib 1件: 280
209 MAP2K1 17件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib 1件: 34
210 MAP2K2 15件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib 1件: 34
211 MAP2K2 15件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
212 MAP2K2 15件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib 1件: 280
213 MAP2K2 15件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib 1件: 34
214 RAF1 14件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Renal cell carcinoma D06272 Sorafenib 2件: 34, 86
215 RAF1 14件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Renal cell carcinoma D08524 Sorafenib 2件: 34, 86
216 MAPK12 18件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
217 MAPK12 18件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8
218 SRC 10件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D03252 Bosutinib 2件: 2, 67
219 SRC 10件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D03658 Dasatinib 2件: 51, 85
220 SRC 10件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D06414 Dasatinib 2件: 51, 85
221 SRC 10件: Rap1 signaling pathway, VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D09664 Saracatinib 3件: 6, 89, 272
222 BRAF 6件: Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Renal cell carcinoma, Thyroid cancer D06272 Sorafenib 2件: 34, 86
223 BRAF 6件: Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Renal cell carcinoma, Thyroid cancer D08524 Sorafenib 2件: 34, 86
224 BRAF 6件: Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Renal cell carcinoma, Thyroid cancer D10064 Dabrafenib 1件: 34
225 VEGFA 6件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D05697 Ranibizumab 4件: 34, 166, 227, 301
226 VEGFA 6件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D06409 Bevacizumab 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331
227 VEGFA 6件: Ras signaling pathway, Rap1 signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D09574 Aflibercept 2件: 90, 166
228 VEGFB 3件: Ras signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway D09574 Aflibercept 2件: 90, 166
229 FGF23 3件: Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton D10913 Burosumab 1件: 238