Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 GAD1 1件: Type I diabetes mellitus D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
2 GAD2 1件: Type I diabetes mellitus D00399 Valproic acid 17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
3 HLA-A 3件: Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
4 HLA-B 3件: Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
5 HLA-C 3件: Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
6 HLA-DMA 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
7 HLA-DMB 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
8 HLA-DOA 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
9 HLA-DOB 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
10 HLA-DPA1 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
11 HLA-DPB1 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
12 HLA-DQA1 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
13 HLA-DQA2 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
14 HLA-DQB1 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
15 HLA-DRA 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
16 HLA-DRB1 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
17 HLA-DRB3 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
18 HLA-DRB4 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
19 HLA-DRB5 2件: Type I diabetes mellitus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
20 HLA-E 3件: Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
21 HLA-F 3件: Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
22 HLA-G 3件: Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
23 IFNG 1件: Type I diabetes mellitus D04242 Fontolizumab 1件: 46
24 IFNG 1件: Type I diabetes mellitus D11120 Emapalumab 2件: 49, 107
25 IL1A 1件: Type I diabetes mellitus D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
26 IL1A 1件: Type I diabetes mellitus D06635 Rilonacept 4件: 51, 106, 107, 266
27 IL1A 1件: Type I diabetes mellitus D11253 Bermekimab 1件: 51
28 IL1B 2件: Type I diabetes mellitus, Yersinia infection D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
29 IL1B 2件: Type I diabetes mellitus, Yersinia infection D06635 Rilonacept 4件: 51, 106, 107, 266
30 IL1B 2件: Type I diabetes mellitus, Yersinia infection D09315 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
31 IL1B 2件: Type I diabetes mellitus, Yersinia infection D09911 Gevokizumab 4件: 41, 50, 56, 269
32 IL12A 1件: Type I diabetes mellitus D09214 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
33 IL12B 1件: Type I diabetes mellitus D09214 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
34 LTA 2件: Viral protein interaction with cytokine and cytokine receptor, Type I diabetes mellitus D00742 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
35 LTA 2件: Viral protein interaction with cytokine and cytokine receptor, Type I diabetes mellitus D10187 Pateclizumab 1件: 46
36 TNF 4件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection D00742 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
37 TNF 4件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection D00754 Thalidomide 20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
38 TNF 4件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
39 TNF 4件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection D02597 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
40 TNF 4件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection D02598 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
41 TNF 4件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection D03441 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271
42 TNF 4件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection D04358 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271
43 TNF 4件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection D04687 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331
44 TNF 4件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection D05393 Pegsunercept 1件: 46
45 TNF 4件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection D08976 Pomalidomide 6件: 28, 34, 51, 85, 227, 331
46 TNF 4件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection D09944 Ozoralizumab 1件: 46
47 CD80 2件: Type I diabetes mellitus, Viral myocarditis D03203 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
48 CD80 2件: Type I diabetes mellitus, Viral myocarditis D03222 Belatacept 1件: 46
49 CD86 2件: Type I diabetes mellitus, Viral myocarditis D03203 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
50 CD86 2件: Type I diabetes mellitus, Viral myocarditis D03222 Belatacept 1件: 46