Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 MASP2 1件: Staphylococcus aureus infection D11531 Narsoplimab 4件: 64, 66, 109, 222
2 CFD 1件: Staphylococcus aureus infection D11641 Danicopan 2件: 62, 222
3 HLA-DMA 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
4 HLA-DMB 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
5 HLA-DOA 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
6 HLA-DOB 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
7 HLA-DPA1 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
8 HLA-DPB1 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
9 HLA-DQA1 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
10 HLA-DQA2 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
11 HLA-DQB1 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
12 HLA-DRA 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
13 HLA-DRB1 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
14 HLA-DRB3 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
15 HLA-DRB4 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
16 HLA-DRB5 8件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
17 IL10 7件: Viral protein interaction with cytokine and cytokine receptor, T cell receptor signaling pathway, Yersinia infection, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
18 ITGAL 2件: Staphylococcus aureus infection, Viral myocarditis D03959 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96
19 PLG 1件: Staphylococcus aureus infection D00160 Aminocaproic acid 1件: 70
20 PLG 1件: Staphylococcus aureus infection D01136 Tranexamic acid 6件: 46, 70, 215, 227, 288, 299
21 PTAFR 1件: Staphylococcus aureus infection D07407 Rupatadine 1件: 46
22 CFB 1件: Staphylococcus aureus infection D12251 Iptacopan 5件: 61, 62, 66, 109, 222
23 C1R 2件: Staphylococcus aureus infection, Systemic lupus erythematosus D10845 Conestat alfa 1件: 61
24 C1S 2件: Staphylococcus aureus infection, Systemic lupus erythematosus D10845 Conestat alfa 1件: 61
25 C1S 2件: Staphylococcus aureus infection, Systemic lupus erythematosus D11530 Sutimlimab 1件: 61
26 C3 4件: Staphylococcus aureus infection, Tuberculosis, Viral carcinogenesis, Systemic lupus erythematosus D11613 Pegcetacoplan 3件: 2, 62, 222
27 C5 2件: Staphylococcus aureus infection, Systemic lupus erythematosus D03940 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222
28 C5 2件: Staphylococcus aureus infection, Systemic lupus erythematosus D11054 Ravulizumab 7件: 2, 11, 13, 50, 62, 66, 109
29 C5 2件: Staphylococcus aureus infection, Systemic lupus erythematosus D11473 Nomacopan 3件: 62, 109, 162
30 C5 2件: Staphylococcus aureus infection, Systemic lupus erythematosus D11477 Pozelimab 2件: 11, 62
31 C5 2件: Staphylococcus aureus infection, Systemic lupus erythematosus D11696 Crovalimab 2件: 62, 109
32 C5 2件: Staphylococcus aureus infection, Systemic lupus erythematosus D11838 Vilobelimab 3件: 43, 44, 269
33 C5AR1 1件: Staphylococcus aureus infection D11093 Avacopan 3件: 43, 44, 222