Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ELANE 2件: Transcriptional misregulation in cancer, Systemic lupus erythematosus D03788 Sivelestat 3件: 13, 85, 96
2 GRIN2A 1件: Systemic lupus erythematosus D00711 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
3 GRIN2A 1件: Systemic lupus erythematosus D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
4 GRIN2A 1件: Systemic lupus erythematosus D00777 Amantadine 4件: 6, 8, 13, 127
5 GRIN2A 1件: Systemic lupus erythematosus D00848 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
6 GRIN2A 1件: Systemic lupus erythematosus D02780 Acamprosate 2件: 6, 206
7 GRIN2A 1件: Systemic lupus erythematosus D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
8 GRIN2A 1件: Systemic lupus erythematosus D03744 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
9 GRIN2A 1件: Systemic lupus erythematosus D04905 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
10 GRIN2A 1件: Systemic lupus erythematosus D07058 Acamprosate 2件: 6, 206
11 GRIN2A 1件: Systemic lupus erythematosus D07283 Esketamine 3件: 2, 4, 70
12 GRIN2A 1件: Systemic lupus erythematosus D07441 Amantadine 4件: 6, 8, 13, 127
13 GRIN2A 1件: Systemic lupus erythematosus D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
14 GRIN2A 1件: Systemic lupus erythematosus D08174 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
15 GRIN2A 1件: Systemic lupus erythematosus D09917 Latrepirdine 1件: 8
16 GRIN2B 1件: Systemic lupus erythematosus D00711 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
17 GRIN2B 1件: Systemic lupus erythematosus D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
18 GRIN2B 1件: Systemic lupus erythematosus D00777 Amantadine 4件: 6, 8, 13, 127
19 GRIN2B 1件: Systemic lupus erythematosus D00848 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
20 GRIN2B 1件: Systemic lupus erythematosus D02780 Acamprosate 2件: 6, 206
21 GRIN2B 1件: Systemic lupus erythematosus D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
22 GRIN2B 1件: Systemic lupus erythematosus D03744 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
23 GRIN2B 1件: Systemic lupus erythematosus D04905 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
24 GRIN2B 1件: Systemic lupus erythematosus D07058 Acamprosate 2件: 6, 206
25 GRIN2B 1件: Systemic lupus erythematosus D07283 Esketamine 3件: 2, 4, 70
26 GRIN2B 1件: Systemic lupus erythematosus D07441 Amantadine 4件: 6, 8, 13, 127
27 GRIN2B 1件: Systemic lupus erythematosus D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
28 GRIN2B 1件: Systemic lupus erythematosus D08174 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
29 GRIN2B 1件: Systemic lupus erythematosus D09917 Latrepirdine 1件: 8
30 HLA-DMA 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
31 HLA-DMB 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
32 HLA-DOA 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
33 HLA-DOB 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
34 HLA-DPA1 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
35 HLA-DPB1 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
36 HLA-DQA1 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
37 HLA-DQA2 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
38 HLA-DQB1 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
39 HLA-DRA 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
40 HLA-DRB1 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
41 HLA-DRB3 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
42 HLA-DRB4 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
43 HLA-DRB5 7件: Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
44 IFNG 8件: TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D04242 Fontolizumab 1件: 46
45 IFNG 8件: TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D11120 Emapalumab 2件: 49, 107
46 IL10 6件: Viral protein interaction with cytokine and cytokine receptor, T cell receptor signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
47 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D00742 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
48 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D00754 Thalidomide 20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
49 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
50 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D02597 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
51 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D02598 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
52 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D03441 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271
53 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D04358 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271
54 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D04687 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331
55 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D05393 Pegsunercept 1件: 46
56 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D08976 Pomalidomide 6件: 28, 34, 51, 85, 227, 331
57 TNF 11件: Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D09944 Ozoralizumab 1件: 46
58 C1R 1件: Systemic lupus erythematosus D10845 Conestat alfa 1件: 61
59 C1S 1件: Systemic lupus erythematosus D10845 Conestat alfa 1件: 61
60 C1S 1件: Systemic lupus erythematosus D11530 Sutimlimab 1件: 61
61 C3 3件: Tuberculosis, Viral carcinogenesis, Systemic lupus erythematosus D11613 Pegcetacoplan 3件: 2, 62, 222
62 C5 1件: Systemic lupus erythematosus D03940 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222
63 C5 1件: Systemic lupus erythematosus D11054 Ravulizumab 7件: 2, 11, 13, 50, 62, 66, 109
64 C5 1件: Systemic lupus erythematosus D11473 Nomacopan 3件: 62, 109, 162
65 C5 1件: Systemic lupus erythematosus D11477 Pozelimab 2件: 11, 62
66 C5 1件: Systemic lupus erythematosus D11696 Crovalimab 2件: 62, 109
67 C5 1件: Systemic lupus erythematosus D11838 Vilobelimab 3件: 43, 44, 269
68 CD80 4件: Toll-like receptor signaling pathway, Type I diabetes mellitus, Systemic lupus erythematosus, Viral myocarditis D03203 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
69 CD80 4件: Toll-like receptor signaling pathway, Type I diabetes mellitus, Systemic lupus erythematosus, Viral myocarditis D03222 Belatacept 1件: 46
70 CD86 5件: Toll-like receptor signaling pathway, Type I diabetes mellitus, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D03203 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
71 CD86 5件: Toll-like receptor signaling pathway, Type I diabetes mellitus, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D03222 Belatacept 1件: 46
72 CD40 5件: Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D11357 Bleselumab 1件: 222
73 CD40 5件: Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D11597 Ravagalimab 2件: 53, 97
74 CD40 5件: Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D11610 Iscalimab 2件: 49, 53
75 CD40LG 4件: T cell receptor signaling pathway, Toxoplasmosis, Systemic lupus erythematosus, Viral myocarditis D06193 Toralizumab 1件: 63