Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ADA 2件: Purine metabolism, Primary immunodeficiency D11017 Elapegademase 1件: 65
2 TNFRSF13C 1件: Primary immunodeficiency D12151 Ianalumab 5件: 35, 46, 49, 53, 95
3 IL2RG 4件: Viral protein interaction with cytokine and cytokine receptor, Th1 and Th2 cell differentiation, Th17 cell differentiation, Primary immunodeficiency D00748 Aldesleukin 6件: 2, 35, 49, 65, 96, 97
4 JAK3 5件: Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral carcinogenesis, Primary immunodeficiency D09970 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
5 JAK3 5件: Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral carcinogenesis, Primary immunodeficiency D10653 Peficitinib 1件: 46
6 LCK 5件: Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Yersinia infection, Primary immunodeficiency D03658 Dasatinib 2件: 51, 85
7 LCK 5件: Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Yersinia infection, Primary immunodeficiency D06414 Dasatinib 2件: 51, 85
8 BTK 1件: Primary immunodeficiency D10223 Ibrutinib 3件: 28, 60, 61
9 BTK 1件: Primary immunodeficiency D10893 Acalabrutinib 2件: 46, 61
10 BTK 1件: Primary immunodeficiency D11422 Zanubrutinib 2件: 300, 331
11 BTK 1件: Primary immunodeficiency D11457 Fenebrutinib 1件: 13
12 BTK 1件: Primary immunodeficiency D11478 Branebrutinib 3件: 46, 49, 53
13 BTK 1件: Primary immunodeficiency D12160 Orelabrutinib 3件: 13, 61, 63
14 CD3D 4件: Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Primary immunodeficiency D05092 Muromonab 3件: 60, 96, 97
15 CD3D 4件: Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Primary immunodeficiency D06314 Visilizumab 2件: 96, 97
16 CD3D 4件: Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Primary immunodeficiency D08959 Otelixizumab 1件: 46
17 CD3E 4件: Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Primary immunodeficiency D05092 Muromonab 3件: 60, 96, 97
18 CD3E 4件: Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Primary immunodeficiency D06314 Visilizumab 2件: 96, 97
19 CD3E 4件: Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Primary immunodeficiency D08959 Otelixizumab 1件: 46
20 CD3E 4件: Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Primary immunodeficiency D11463 Mosunetuzumab 1件: 49
21 CD19 1件: Primary immunodeficiency D11757 Inebilizumab 4件: 11, 13, 51, 300
22 CD40 6件: Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Primary immunodeficiency, Viral myocarditis D11357 Bleselumab 1件: 222
23 CD40 6件: Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Primary immunodeficiency, Viral myocarditis D11597 Ravagalimab 2件: 53, 97
24 CD40 6件: Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Primary immunodeficiency, Viral myocarditis D11610 Iscalimab 2件: 49, 53
25 CD40LG 5件: T cell receptor signaling pathway, Toxoplasmosis, Systemic lupus erythematosus, Primary immunodeficiency, Viral myocarditis D06193 Toralizumab 1件: 63