Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Fat digestion and absorption 💬 Related to 2 target genes, 2 drugs (DrugBank) and 4 diseases in DDrare |
MTTP 1件: MTTP 💬 |
D09637 D09637 💬 |
Lomitapide | 079 1件: 79 💬 |
| 2 | Fat digestion and absorption 💬 Related to 2 target genes, 2 drugs (DrugBank) and 4 diseases in DDrare |
NPC1L1 1件: NPC1L1 💬 |
D01966 D01966 💬 |
Ezetimibe | 049 4件: 49, 79, 93, 260 💬 |
| 3 | Fatty acid degradation 💬 Related to 7 target genes, 2 drugs (DrugBank) and 3 diseases in DDrare |
ADH1A 3件: ADH1A, ADH1B, ADH1C 💬 |
D00707 D00707 💬 |
Fomepizole | 301 1件: 301 💬 |
| 4 | Fatty acid degradation 💬 Related to 7 target genes, 2 drugs (DrugBank) and 3 diseases in DDrare |
CPT1A 4件: CPT1A, CPT1B, CPT1C, CPT2 💬 |
D05442 D05442 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
| 5 | Fatty acid degradation 💬 Related to 7 target genes, 2 drugs (DrugBank) and 3 diseases in DDrare |
CPT1A 4件: CPT1A, CPT1B, CPT1C, CPT2 💬 |
D08340 D08340 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
| 6 | Fatty acid metabolism 💬 Related to 4 target genes, 1 drug (DrugBank) and 2 diseases in DDrare |
CPT1A 4件: CPT1A, CPT1B, CPT1C, CPT2 💬 |
D05442 D05442 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
| 7 | Fatty acid metabolism 💬 Related to 4 target genes, 1 drug (DrugBank) and 2 diseases in DDrare |
CPT1A 4件: CPT1A, CPT1B, CPT1C, CPT2 💬 |
D08340 D08340 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
| 8 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
ALOX5 1件: ALOX5 💬 |
D01773 D01773 💬 |
Oxatomide | 113 1件: 113 💬 |
| 9 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
ALOX5 1件: ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 3件: 85, 160, 164 💬 |
| 10 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
BTK 1件: BTK 💬 |
D10893 D10893 💬 |
Acalabrutinib | 046 2件: 46, 61 💬 |
| 11 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
BTK 1件: BTK 💬 |
D11478 D11478 💬 |
Branebrutinib | 046 3件: 46, 49, 53 💬 |
| 12 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
BTK 1件: BTK 💬 |
D11457 D11457 💬 |
Fenebrutinib | 013 1件: 13 💬 |
| 13 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
BTK 1件: BTK 💬 |
D10223 D10223 💬 |
Ibrutinib | 028 3件: 28, 60, 61 💬 |
| 14 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 3件: 13, 61, 63 💬 |
| 15 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
BTK 1件: BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 300 2件: 300, 331 💬 |
| 16 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
CSF2 1件: CSF2 💬 |
D11343 D11343 💬 |
Otilimab | 046 2件: 46, 256 💬 |
| 17 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
FCER1A 1件: FCER1A 💬 |
D05251 D05251 💬 |
Omalizumab | 046 7件: 46, 53, 65, 98, 162, 226, 299 💬 |
| 18 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
FYN 1件: FYN 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 19 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
FYN 1件: FYN 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 20 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
IL13 1件: IL13 💬 |
D08857 D08857 💬 |
Anrukinzumab | 097 1件: 97 💬 |
| 21 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
IL13 1件: IL13 💬 |
D09633 D09633 💬 |
Lebrikizumab | 085 1件: 85 💬 |
| 22 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
IL13 1件: IL13 💬 |
D09979 D09979 💬 |
Tralokinumab | 085 2件: 85, 97 💬 |
| 23 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
IL4 1件: IL4 💬 |
D03117 D03117 💬 |
Binetrakin | 046 1件: 46 💬 |
| 24 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
IL5 1件: IL5 💬 |
D04923 D04923 💬 |
Mepolizumab | 044 4件: 44, 45, 98, 162 💬 |
| 25 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
IL5 1件: IL5 💬 |
D08985 D08985 💬 |
Reslizumab | 044 2件: 44, 98 💬 |
| 26 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
| 27 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
| 28 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
| 29 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
| 30 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 2件: 113, 222 💬 |
| 31 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 1件: 8 💬 |
| 32 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
| 33 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
| 34 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 35 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 36 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
SYK 1件: SYK 💬 |
D09347 D09347 💬 |
Fostamatinib | 046 4件: 46, 49, 61, 66 💬 |
| 37 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
| 38 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
| 39 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
| 40 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
| 41 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
| 42 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 |
| 43 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 1件: 46 💬 |
| 44 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 1件: 46 💬 |
| 45 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 46 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬 |
| 47 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
| 48 | Fc gamma R-mediated phagocytosis 💬 Related to 8 target genes, 9 drugs (DrugBank) and 13 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
| 49 | Fc gamma R-mediated phagocytosis 💬 Related to 8 target genes, 9 drugs (DrugBank) and 13 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
| 50 | Fc gamma R-mediated phagocytosis 💬 Related to 8 target genes, 9 drugs (DrugBank) and 13 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
| 51 | Fc gamma R-mediated phagocytosis 💬 Related to 8 target genes, 9 drugs (DrugBank) and 13 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
| 52 | Fc gamma R-mediated phagocytosis 💬 Related to 8 target genes, 9 drugs (DrugBank) and 13 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
| 53 | Fc gamma R-mediated phagocytosis 💬 Related to 8 target genes, 9 drugs (DrugBank) and 13 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
| 54 | Fc gamma R-mediated phagocytosis 💬 Related to 8 target genes, 9 drugs (DrugBank) and 13 diseases in DDrare |
PRKCD 2件: PRKCD, PRKCE 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 1件: 97 💬 |
| 55 | Fc gamma R-mediated phagocytosis 💬 Related to 8 target genes, 9 drugs (DrugBank) and 13 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 56 | Fc gamma R-mediated phagocytosis 💬 Related to 8 target genes, 9 drugs (DrugBank) and 13 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 57 | Fc gamma R-mediated phagocytosis 💬 Related to 8 target genes, 9 drugs (DrugBank) and 13 diseases in DDrare |
SYK 1件: SYK 💬 |
D09347 D09347 💬 |
Fostamatinib | 046 4件: 46, 49, 61, 66 💬 |
| 58 | Ferroptosis 💬 Related to 2 target genes, 2 drugs (DrugBank) and 2 diseases in DDrare |
HMOX1 1件: HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 59 | Ferroptosis 💬 Related to 2 target genes, 2 drugs (DrugBank) and 2 diseases in DDrare |
TFRC 1件: TFRC 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 1件: 19 💬 |
| 60 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
ACVR2A 1件: ACVR2A 💬 |
D09670 D09670 💬 |
Sotatercept | 086 2件: 86, 284 💬 |
| 61 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
ACVR2A 2件: ACVR2A, ACVR2B 💬 |
D10620 D10620 💬 |
Bimagrumab | 015 1件: 15 💬 |
| 62 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
BCL2 1件: BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 1件: 28 💬 |
| 63 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
BMPR2 1件: BMPR2 💬 |
D03779 D03779 💬 |
Dibotermin alfa | 034 1件: 34 💬 |
| 64 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
CCL2 4件: CCL2, IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 65 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
HMOX1 1件: HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 66 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 2件: 49, 107 💬 |
| 67 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 1件: 46 💬 |
| 68 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IL1A 1件: IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 1件: 51 💬 |
| 69 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
| 70 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
| 71 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
| 72 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
| 73 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
KDR 1件: KDR 💬 |
D03218 D03218 💬 |
Axitinib | 034 1件: 34 💬 |
| 74 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
KDR 1件: KDR 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 1件: 34 💬 |
| 75 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
KDR 1件: KDR 💬 |
D08881 D08881 💬 |
Cediranib | 034 1件: 34 💬 |
| 76 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
KDR 1件: KDR 💬 |
D10481 D10481 💬 |
Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬 |
| 77 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
KDR 1件: KDR 💬 |
D06272 D06272 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 78 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
KDR 1件: KDR 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 79 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
KDR 1件: KDR 💬 |
D06402 D06402 💬 |
Sunitinib | 028 2件: 28, 34 💬 |
| 80 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
KDR 1件: KDR 💬 |
D08552 D08552 💬 |
Sunitinib | 028 2件: 28, 34 💬 |
| 81 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
KDR 1件: KDR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 1件: 67 💬 |
| 82 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
KEAP1 1件: KEAP1 💬 |
D03846 D03846 💬 |
Dimethyl fumarate | 013 5件: 13, 49, 51, 86, 296 💬 |
| 83 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
MAP3K5 1件: MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 1件: 86 💬 |
| 84 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 2件: 113, 222 💬 |
| 85 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 1件: 8 💬 |
| 86 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
NFE2L2 1件: NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 1件: 18 💬 |
| 87 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
NFKB1 1件: NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 4件: 46, 51, 53, 271 💬 |
| 88 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
| 89 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
| 90 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
| 91 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
| 92 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
| 93 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 24件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
| 94 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 24件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
| 95 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
RELA 1件: RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 1件: 113 💬 |
| 96 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
SRC 1件: SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 2件: 2 , 67 💬 |
| 97 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
SRC 1件: SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 98 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
SRC 1件: SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 99 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
SRC 1件: SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 3件: 6 , 89, 272 💬 |
| 100 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
| 101 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
| 102 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
| 103 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
| 104 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
| 105 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 |
| 106 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 1件: 46 💬 |
| 107 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 1件: 46 💬 |
| 108 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬 |
| 109 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
| 110 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
VEGFA 1件: VEGFA 💬 |
D09574 D09574 💬 |
Aflibercept | 090 2件: 90, 166 💬 |
| 111 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
VEGFA 1件: VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
| 112 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
VEGFA 1件: VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 4件: 34, 166, 227, 301 💬 |
| 113 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
BCL2 1件: BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 1件: 28 💬 |
| 114 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
BRAF 1件: BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 1件: 34 💬 |
| 115 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
BRAF 5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 116 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
BRAF 5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 117 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 5件: 34, 51, 86, 89, 331 💬 |
| 118 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 1件: 94 💬 |
| 119 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 1件: 94 💬 |
| 120 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
| 121 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 1件: 34 💬 |
| 122 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
| 123 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
| 124 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
EGFR 4件: EGFR, ERBB2, FLT4, KDR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 1件: 67 💬 |
| 125 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
FLT1 3件: FLT1, FLT4, KDR 💬 |
D03218 D03218 💬 |
Axitinib | 034 1件: 34 💬 |
| 126 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
FLT1 3件: FLT1, FLT4, KDR 💬 |
D08881 D08881 💬 |
Cediranib | 034 1件: 34 💬 |
| 127 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
FLT1 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬 |
| 128 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
FLT1 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D06402 D06402 💬 |
Sunitinib | 028 2件: 28, 34 💬 |
| 129 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
FLT1 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 2件: 28, 34 💬 |
| 130 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
FYN 3件: FYN, PDGFRB, SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 131 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
FYN 3件: FYN, PDGFRB, SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 132 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 1件: 232 💬 |
| 133 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
| 134 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
| 135 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 1件: 51 💬 |
| 136 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06590 D06590 💬 |
Firategrast | 013 1件: 13 💬 |
| 137 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
| 138 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ITGA4 2件: ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 2件: 96, 97 💬 |
| 139 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ITGA4 2件: ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 3件: 94, 96, 97 💬 |
| 140 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ITGB7 1件: ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 2件: 96, 97 💬 |
| 141 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
KDR 2件: KDR, MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 1件: 34 💬 |
| 142 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
| 143 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
| 144 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
| 145 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
| 146 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 147 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 148 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
PDGFRA 2件: PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
| 149 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
PGF 3件: PGF, VEGFA, VEGFB 💬 |
D09574 D09574 💬 |
Aflibercept | 090 2件: 90, 166 💬 |
| 150 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
| 151 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
| 152 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
| 153 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ROCK2 1件: ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 1件: 51 💬 |
| 154 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
SRC 1件: SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 2件: 2 , 67 💬 |
| 155 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
SRC 1件: SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 3件: 6 , 89, 272 💬 |
| 156 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
VEGFA 1件: VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
| 157 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
VEGFA 1件: VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 4件: 34, 166, 227, 301 💬 |
| 158 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
VWF 1件: VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 1件: 64 💬 |
| 159 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
ALPL 1件: ALPL 💬 |
D10595 D10595 💬 |
Asfotase alfa | 172 1件: 172 💬 |
| 160 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
| 161 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
| 162 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
PAH 1件: PAH 💬 |
D11077 D11077 💬 |
Pegvaliase | 240 1件: 240 💬 |
| 163 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
TPH1 2件: TPH1, TPH2 💬 |
D09973 D09973 💬 |
Telotristat | 097 1件: 97 💬 |
| 164 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
BRAF 1件: BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 1件: 34 💬 |
| 165 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 166 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 167 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 5件: 34, 51, 86, 89, 331 💬 |
| 168 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 1件: 94 💬 |
| 169 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 1件: 94 💬 |
| 170 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
| 171 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 1件: 34 💬 |
| 172 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
| 173 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
| 174 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 1件: 67 💬 |
| 175 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 1件: 232 💬 |
| 176 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
| 177 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
| 178 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 1件: 51 💬 |
| 179 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
IL10 2件: IL10, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 180 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
IL6 1件: IL6 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬 |
| 181 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
IL6 1件: IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 2件: 28, 331 💬 |
| 182 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
| 183 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
| 184 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
| 185 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
INSR 1件: INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 2件: 96, 156 💬 |
| 186 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
INSR 1件: INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 2件: 96, 156 💬 |
| 187 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
| 188 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
| 189 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
| 190 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
| 191 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 2件: 113, 222 💬 |
| 192 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 1件: 8 💬 |
| 193 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
| 194 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
| 195 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
PLK1 1件: PLK1 💬 |
D10154 D10154 💬 |
Rigosertib | 036 1件: 36 💬 |
| 196 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 24件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
| 197 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 24件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
| 198 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
S1PR1 1件: S1PR1 💬 |
D11283 D11283 💬 |
Cenerimod | 049 1件: 49 💬 |
| 199 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
S1PR1 1件: S1PR1 💬 |
D10001 D10001 💬 |
Fingolimod | 013 3件: 13, 14, 156 💬 |
| 200 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
S1PR1 1件: S1PR1 💬 |
D11215 D11215 💬 |
Ponesimod | 013 1件: 13 💬 |
| 201 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
S1PR1 1件: S1PR1 💬 |
D11460 D11460 💬 |
Siponimod | 013 2件: 13, 50 💬 |
| 202 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
S1PR1 2件: S1PR1, S1PR4 💬 |
D10930 D10930 💬 |
Etrasimod | 096 3件: 96, 97, 98 💬 |
| 203 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
S1PR1 2件: S1PR1, S1PR4 💬 |
D10968 D10968 💬 |
Ozanimod | 013 3件: 13, 96, 97 💬 |
| 204 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare |
TGFB1 3件: TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 4件: 51, 85, 222, 274 💬 |