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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
118 FDG----[1] 145
2Acetate[1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
3ACTH[1] Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 13, 66, 145, 193, 222
4Adrenocorticotropin hormone----[1] 145
5AMZ002----[1] 145
6Cannabidiol[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[18] 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
7Cannabidiol (CBD)[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[7] 6, 13, 140, 144, 145, 156, 158
8Cannabidiol Oral Solution[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[4] 140, 144, 145, 193
9CBD----[12] 2, 6, 8, 13, 36, 46, 140, 144, 145, 156, 158, 206
10Combination therapy with vigabatrin and prednisolone[2] Prednisolone,
Vigabatrin		[9] D00472 ,
D00535 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[2] ABAT,
NR3C1 💬		[8] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Neuroactive ligand-receptor interaction, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[1] 145
11Cosyntropin[1] Tetracosactide[1] D00284 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 83, 113, 145
12Cosyntropin Injectable Suspension 1 MG/ML + vigabatrin[2] Tetracosactide,
Vigabatrin		[2] D00284 ,
D00535 		[2] ABAT,
MC2R 💬		[12] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, Metabolic pathways, Neuroactive ligand-receptor interaction, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, cAMP signaling pathway 💬[1] 145
13Cosyntropin Injectable Suspension, 1 mg/mL[1] Tetracosactide[1] D00284 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 145
14Decortin H----[3] 66, 97, 145
15FENFLURAMINE[1] Fenfluramine[1] D07945 [4] HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬		[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[4] 140, 144, 145, 149
16Ganaxolone[1] Ganaxolone[1] D04300 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[4] 145, 152, 158, 206
17GWP42003-P----[5] 140, 144, 145, 156, 158
18Intravenous Methylprednisolone[1] Methylprednisolone[6] D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 13, 145
19JBPOS0101[1] JBPOS0101---[1] 145
20Ketogenic diet----[2] 145, 230
21M071754----[1] 145
22Melatonin[1] Melatonin[1] D08170 [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 90, 97, 144, 145, 149, 202
23Methylprednisolone[1] Methylprednisolone[6] D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
24Modified Atkins diet----[3] 145, 157, 187
25Null----[16] 6, 13, 15, 28, 37, 46, 49, 51, 63, 86, 90, 96, 97, 107, 145, 271
26Oral Pednisolone----[1] 145
27Oral prednisolone[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 49, 96, 145
28Other: modified Atkins diet----[1] 145
29PREDNISOLONE[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
30PYRIDOXINE[1] Pyridoxine[2] D02179 ,
D08454 		--[3] 93, 145, 320
31Pyridoxine plus prednisolone[2] Prednisolone,
Pyridoxine		[10] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D02179 ,
D03301 ,
D08454 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 145
32Radiprodil[1] Radiprodil---[1] 145
33SABRIL[1] Vigabatrin[1] D00535 [1] ABAT 💬[7] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[2] 145, 158
34Sabril granules for oral use[1] Vigabatrin[1] D00535 [1] ABAT 💬[7] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[1] 145
35SABRIL SACHETS[1] Vigabatrin[1] D00535 [1] ABAT 💬[7] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[1] 145
36Sabrilex----[1] 145
37Sabril®[1] Vigabatrin[1] D00535 [1] ABAT 💬[7] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[1] 145
38SOLUBLE PREDNISOLONE TABLETS[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 145
39SPT3162----[1] 145
40Synacthen Depot[1] Tetracosactide[1] D00284 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 83, 145, 222
41Tetracosactide[1] Tetracosactide[1] D00284 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[4] 83, 113, 145, 222
42Tetracosactide acetate[2] Acetate,
Tetracosactide		[1] D00284 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[2] 83, 145
43Tricaprilin[1] Tricaprylin---[1] 145
44UCB3491----[1] 145
45VGB-ST----[1] 145
46VGB-ST soluble tablets----[1] 145
47VIGABATRIN[1] Vigabatrin[1] D00535 [1] ABAT 💬[7] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[2] 145, 158
48Vigabatrin Tablets[1] Vigabatrin[1] D00535 [1] ABAT 💬[7] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[1] 145
49Vigabatrin: Vigabatrin new ST formulation then Sabril®[1] Vigabatrin[1] D00535 [1] ABAT 💬[7] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[1] 145
50Vitamin B1[1] Thiamine[1] D08580 --[1] 145