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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Bosentan[1] Bosentan[2] D01227 ,
D07538
[2] EDNRA,
EDNRB 💬
[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
2DEXMEDETOMIDINE[1] Dexmedetomidine[2] D00514 ,
D01205
[3] ADRA2A,
ADRA2B,
ADRA2C 💬
[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[13] 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
3Liothyronine[1] Liothyronine[2] D01011 ,
D08128
[2] THRA,
THRB 💬
[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[3] 13, 210, 212
4Liothyronine I 131[2] Liothyronine,
Liothyronine I-131
[2] D01011 ,
D08128
[2] THRA,
THRB 💬
[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[2] 210, 212
5MBT----[1] 212
6Methacetin Breath Test (MBT)----[1] 212
7Sildenafil[1] Sildenafil[2] D02229 ,
D08514
[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
8Vitamin C[1] Ascorbic acid[1] D00018 --[6] 10, 192, 206, 210, 211, 212