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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1ACE I, ATA II and Statins----[1] 218
2ACE-inhibitor----[1] 218
3AT1-inhibitor----[1] 218
4ATRASENTAN[1] Atrasentan---[3] 66, 218, 222
5Bardoxolone[1] Bardoxolone[1] D09584 --[7] 66, 67, 84, 85, 86, 218, 222
6Bardoxolone methyl[2] Bardoxolone,
Bardoxolone methyl
[2] D09584 ,
D09585
--[7] 66, 67, 84, 85, 86, 218, 222
7Benazepril[1] Benazepril[2] D00620 ,
D07499
[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 49, 57, 218, 224
8Benazepril hydrochloride 10 milligram (mg) Tab[1] Benazepril[2] D00620 ,
D07499
[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 218
9Benazepril, Valsartan and Fluvastatin[3] Benazepril,
Fluvastatin,
Valsartan
[5] D00400 ,
D00620 ,
D00892 ,
D07499 ,
D07983
[3] ACE,
AGTR1,
HMGCR 💬
[22] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Bile secretion, Calcium signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Terpenoid backbone biosynthesis, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 218
10Delix----[1] 218
11Fluvastatin[1] Fluvastatin[2] D00892 ,
D07983
[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 79, 218, 222
12Gold[1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318
13HMG-Coenzyme inhibitor (statin)----[1] 218
14Hydroxychloroquine[1] Hydroxychloroquine[1] D08050 --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
15Hydroxychloroquine Sulfate 100 milligram (mg) Tab[2] Hydroxychloroquine,
Sulfate ion
[1] D08050 --[1] 218
16Lademirsen----[1] 218
17Lademirsen (SAR339375)----[1] 218
18Paricalcitol[1] Paricalcitol[1] D00930 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[4] 19, 66, 218, 238
19R3R01----[2] 218, 222
20Ramipril[1] Ramipril[1] D00421 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257
21RE-021----[3] 66, 218, 222
22RG-012----[1] 218
23RG012----[1] 218
24RTA 402----[3] 67, 86, 218
25SAR339375----[1] 218
26SPARSENTAN[1] Sparsentan[1] D11776 [2] AGTR1,
EDNRA 💬
[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 66, 218, 222
27Spironolactone[1] Spironolactone[1] D00443 [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[7] 58, 67, 86, 113, 210, 218, 225
28Sulfate[1] Sulfate ion---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 218, 222, 226, 265, 296, 297, 299
29Valsartan[1] Valsartan[1] D00400 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 57, 58, 66, 75, 218, 222, 224