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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1ALN-65585----[1] 234
2ALN-GO1----[1] 234
3CA----[1] 234
4CALD HR-D (High-Risk, Regimen C)----[5] 19, 20, 125, 234, 326
5CALD HR-D (High-Risk, Regimen D)----[5] 19, 20, 125, 234, 326
6CALD SR-A (Standard-Risk, Regimen A)----[5] 19, 20, 125, 234, 326
7CALD SR-B (Standard-Risk, Regimen B)----[5] 19, 20, 125, 234, 326
8Campath[1] Alemtuzumab[1] D02802 [1] CD52 💬-[12] 19, 20, 49, 51, 60, 62, 65, 164, 234, 283, 285, 326
9Campath-1H[1] Alemtuzumab[1] D02802 [1] CD52 💬-[6] 19, 20, 60, 234, 285, 326
10Chenodeoxycholic acid[1] Chenodeoxycholic acid[1] D00163 [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 96, 234, 263
11Cholic Acid[1] Cholic Acid[1] D10699 [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 234, 265, 310
12Cholic Acids----[2] 20, 234
13Clofarabine[1] Clofarabine[1] D03546 [3] POLA1,
POLA2,
RRM1 💬		[6] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[9] 19, 20, 40, 46, 49, 60, 96, 234, 326
14Cyclosporine[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
15Cyclosporine A[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[11] 19, 20, 36, 49, 50, 53, 58, 60, 107, 234, 283
16DCR-1171X----[1] 234
17DCR-L1360----[1] 234
18DCR-PH1----[1] 234
19DCR-PHXC----[1] 234
20Hematopoietic Stem Cell Transplantation----[13] 11, 13, 14, 19, 20, 35, 46, 49, 51, 65, 96, 234, 285
21Hydroxychloroquine[1] Hydroxychloroquine[1] D08050 --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
22IMD----[5] 19, 20, 125, 234, 326
23IMD Preparative Regimen----[5] 19, 20, 125, 234, 326
24LUMASIRAN[1] Lumasiran[1] D11925 [1] HAO1 💬[4] Carbon metabolism, Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Peroxisome 💬[1] 234
25Melphalan[1] Melphalan[1] D00369 --[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299
26Mycophenolate[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
27Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[4] D00752 ,
D05094 ,
D05095 ,
D05096 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
28Nedosiran----[1] 234
29Osteopetrosis Haploidentical Only Preparative Regimen----[5] 19, 20, 125, 234, 326
30Osteopetrosis Only Preparative Regimen----[5] 19, 20, 125, 234, 326
31Radiation: Total Body Irradiation with Marrow Boosting----[2] 19, 234
32Stem Cell Transplantation----[13] 13, 19, 20, 46, 51, 60, 62, 65, 90, 125, 164, 234, 326
33Sterile Normal Saline (0.9% NaCl)----[3] 62, 234, 254
34Ursodiol[1] Ursodeoxycholic acid[1] D00734 [1] NR1H4 💬[1] Bile secretion 💬[6] 8, 20, 93, 97, 234, 299