1 | (R)-tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4- yl)pyridine-2-yl)pyrrolo[1,2-b]pyridazin-4-yl)piperazine-1-carboxylate sesquisuccinate | [1] Piperazine Piperazine | [6] D00807
D00807
,
D01393
,
D02127
,
D02145
,
D05486
,
D06224
| - | - | [1] 272 272 |
2 | (R)-tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4- yl)pyridine-2yl)pyrrolo[1,2-b]pyridazin-4-yl)piperazine-1-carboxylate | [1] Piperazine Piperazine | [6] D00807
D00807
,
D01393
,
D02127
,
D02145
,
D05486
,
D06224
| - | - | [1] 272 272 |
3 | AZD0530 | - | - | - | - | [1] 272 272 |
4 | AZD0530 Difumarate | - | - | - | - | [1] 272 272 |
5 | DS-6016a | - | - | - | - | [1] 272 272 |
6 | Garetosmab | [1] Garetosmab Garetosmab | [1] D11443
D11443
| - | - | [1] 272 272 |
7 | INCB000928 | - | - | - | - | [1] 272 272 |
8 | INCB000928 fumarate dihydrate | - | - | - | - | [1] 272 272 |
9 | IPN60120 | - | - | - | - | [1] 272 272 |
10 | IPN60130 | - | - | - | - | [1] 272 272 |
11 | IPN60130 10 mg capsules | - | - | - | - | [1] 272 272 |
12 | IPN60130 50 mg capsules | - | - | - | - | [1] 272 272 |
13 | Midazolam | [1] Midazolam Midazolam | [3] D00550
D00550
,
D00696
,
D05028
| [16] GABRA1 GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 | [7] GABAergic synapse GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬 | [12] 2 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298 |
14 | PALOVAROTENE | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
15 | PALOVAROTENE - 1.5mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
16 | PALOVAROTENE - 10 mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
17 | PALOVAROTENE - 1mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
18 | PALOVAROTENE - 2 mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
19 | PALOVAROTENE - 2.5 mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
20 | PALOVAROTENE - 3 mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
21 | PALOVAROTENE - 4 mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
22 | PALOVAROTENE - 5 mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
23 | PALOVAROTENE 1.5 mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
24 | Palovarotene dose level 1 | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
25 | Palovarotene dose level 2 | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
26 | Palovarotene dose level 3 | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
27 | Palovarotene dose level 4 | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
28 | PALOVAROTENE-2 mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
29 | PALOVAROTENE-3 mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
30 | PALOVAROTENE-4 mg | [1] Palovarotene Palovarotene | [1] D09365
D09365
| [1] RARG RARG 💬 | - | [1] 272 272 |
31 | Perhexiline | [1] Perhexiline Perhexiline | [2] D05442
D05442
,
D08340
| [8] CACNA1C CACNA1C, CACNA1D, CACNA1F, CACNA1S, CPT1A, CPT1B, CPT1C, CPT2 💬 | [47] AMPK signaling pathway AMPK signaling pathway, Adipocytokine signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Dopaminergic synapse, Fatty acid degradation, Fatty acid metabolism, GABAergic synapse, Glucagon signaling pathway, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin resistance, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, PPAR signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Thermogenesis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [2] 58 58, 272 |
32 | Piperazine | [1] Piperazine Piperazine | [6] D00807
D00807
,
D01393
,
D02127
,
D02145
,
D05486
,
D06224
| - | - | [2] 58 58, 272 |
33 | REGN2477 | - | - | - | - | [1] 272 272 |
34 | Saracatinib | [1] Saracatinib Saracatinib | [1] D09664
D09664
| [2] ABL1 ABL1, SRC 💬 | [49] Adherens junction Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬 | [3] 6 6, 89, 272 |
35 | SARACATINIB DIFUMARATE | [1] Saracatinib Saracatinib | [1] D09664
D09664
| [2] ABL1 ABL1, SRC 💬 | [49] Adherens junction Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬 | [1] 272 272 |