Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(7R,8R,9R)-2.3-Dimethyl-8-hydroxy-7(2-methoxyethoxy)- 9-phenyl-7.8.9.10-tetrahydro-imidazo-[1.2-h].[1.7].- naphthyridine----[1] 301
24-Methylpyrazole[1] Fomepizole[1] D00707 [3] ADH1A,
ADH1B,
ADH1C 💬		[9] Alcoholic liver disease, Drug metabolism - cytochrome P450, Fatty acid degradation, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pyruvate metabolism, Retinol metabolism, Tyrosine metabolism 💬[1] 301
3ACU-4429----[1] 301
4ALK-001----[1] 301
5ALK-001 (No generic name)----[1] 301
6ARC1905----[1] 301
7ARC1905 20 MG/ML----[1] 301
8Avacincaptad pegol[1] Avacincaptad pegol---[1] 301
9DHA----[8] 6, 46, 48, 49, 94, 113, 299, 301
10Diagnostic Test: Ocular Coherence Tomography-Angiography (OCT-A)----[2] 90, 301
11Docosahexaenoic acid[1] Doconexent---[7] 6, 49, 90, 94, 240, 299, 301
12Docosahexaenoic Acid (DHA) Dietary Supplement[1] Doconexent---[1] 301
13Emixustat[1] Emixustat[1] D10348 --[1] 301
14Emixustat hydrochloride[1] Emixustat[1] D10348 --[1] 301
15EMIXUSTAT HYDROCHLORIDE (ACU-4429)[1] Emixustat[1] D10348 --[1] 301
16EPA----[6] 8, 46, 48, 49, 113, 301
17EU/3/13/1208 orphan----[1] 301
18HESC-RPE----[1] 301
19Interferon Gamma[1] Interferon Gamma---[8] 18, 65, 85, 107, 228, 299, 301, 326
20INTERFERON GAMMA-1B[2] Interferon Gamma,
Interferon gamma-1b		[1] D00747 [2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326
21Lentiviral vector containing ABCA4 gene----[1] 301
22Long term follow up in all patients who received SAR422459 in previous study TDU13583----[1] 301
23MA09-hRPE----[1] 301
24Madeos----[1] 301
25Metformin[1] Metformin[2] D00944 ,
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
26METFORMIN HYDROCHLORIDE[1] Metformin[2] D00944 ,
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[5] 81, 158, 265, 299, 301
27Other: Saline----[8] 2, 6, 46, 97, 98, 256, 274, 301
28Other: Sham----[1] 301
29Other: Standard of Care Sildenafil[1] Sildenafil[2] D02229 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[2] 90, 301
30Other: Visual Acuity (VA)----[2] 90, 301
31Over the counter DHA/EPA dietary supplementation----[1] 301
32Ranibizumab[1] Ranibizumab[1] D05697 [1] VEGFA 💬[24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[4] 34, 166, 227, 301
33Ranibizumab injection (0.5 mg)[1] Ranibizumab[1] D05697 [1] VEGFA 💬[24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[2] 166, 301
34Saffron supplementation----[1] 301
35SAR422459----[1] 301
36Sildenafil[1] Sildenafil[2] D02229 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
37SORAPRAZAN----[1] 301
38StarGen----[1] 301
39Stem/progenitor cells transplantation----[2] 90, 301
40STG-001[1] STG-001---[1] 301
41Tinlarebant----[1] 301
42VA----[3] 90, 301, 302
43Vett Lentiviral con gene ABCA4----[1] 301
44Zimura----[1] 301