Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
15% lidocaine/5 mg/ml 0.02% estradiol compound cream
(Synonym: D04064)		[2] Estradiol,
Lidocaine		[11] D00105 ,
D00358 ,
D01413 ,
D01617 ,
D01953 ,
D02086 ,
D04061 ,
D04063 ,
D04064 ,
D04065 ,
D08127 		[7] ESR1,
ESR2,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[13] Adrenergic signaling in cardiomyocytes, Breast cancer, Chemical carcinogenesis - receptor activation, Dopaminergic synapse, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Taste transduction, Thyroid hormone signaling pathway 💬[1] 226
2Estradiol
(Synonym: D04064)		[1] Estradiol[8] D00105 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[7] 13, 46, 49, 65, 76, 226, 299
3Estradiol 2 mg
(Synonym: D04064)		[1] Estradiol[8] D00105 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 299
4ESTRADIOL HEMIHYDRATE
(Synonym: D04064)		[1] Estradiol[8] D00105 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 13
5Estradiol valerate
(Synonym: D04064)		[2] Estradiol,
Estradiol valerate		[8] D00105 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 65
6Ethinyl estradiol
(Synonym: D04064)		[2] Estradiol,
Ethinylestradiol		[9] D00105 ,
D00554 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[3] 46, 49, 299
7Loestrin (norethindrone acetate and ethinyl estradiol)
(Synonym: D04064)		[4] Acetate,
Estradiol,
Ethinylestradiol,
Norethisterone		[11] D00105 ,
D00182 ,
D00554 ,
D00953 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[3] ESR1,
ESR2,
PGR 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 299
8Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 µg ethinyl estradiol)
(Synonym: D04064)		[4] Acetate,
Estradiol,
Ethinylestradiol,
Norethisterone		[11] D00105 ,
D00182 ,
D00554 ,
D00953 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[3] ESR1,
ESR2,
PGR 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 46, 49
9Ortho-cyclen, Ethinyl estradiol/norgestimate, 0.035 mg/0.250 mg
(Synonym: D04064)		[3] Estradiol,
Ethinylestradiol,
Norgestimate		[10] D00105 ,
D00554 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 ,
D05209 		[3] ESR1,
ESR2,
PGR 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 299
10Somatropin, Clonidine, L-Arginin-Hydrochloride, Estradiol valerate
(Synonym: D04064)		[5] Arginine,
Clonidine,
Estradiol,
Estradiol valerate,
Somatotropin		[12] D00105 ,
D00281 ,
D00604 ,
D01413 ,
D01617 ,
D01953 ,
D02691 ,
D02982 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[6] ADRA2A,
ADRA2B,
ADRA2C,
ESR1,
ESR2,
GHR 💬		[16] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway, cGMP-PKG signaling pathway 💬[1] 65