203. 22q11.2欠失症候群 22q11.2 deletion syndrome Clinical trials / Disease details


臨床試験数 : 5 薬物数 : 7 - (DrugBank : 1) / 標的遺伝子数 : 14 - 標的パスウェイ数 : 23

  
No.TrialIDDate_
enrollment
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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agemax
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PhaseCountries
1EUCTR2021-002011-61-NL
(EUCTR)
13/08/202121/06/2021Riluzole as treatment for psychotic and cognitive symptoms in 22q11.2 deletion syndromeThe glutamate/GABA balance as novel therapeutic target for psychotic and cognitive symptoms in 22q11.2 deletion syndrome - Riluzole in 22q11.2DS 22q11.2 deletion syndrome;Therapeutic area: Psychiatry and Psychology [F] - Mental Disorders [F03]Trade Name: Rilutek
Product Name: Riluzole
Product Code: EMEA/H/C/000109
Academisch ziekenhuis MaastrichtNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
45Phase 3Netherlands
2NCT05149898
(ClinicalTrials.gov)
March 3, 20205/10/2021Open-Label, Tolerability and Efficacy Study of ZYN002 Administered as a Transdermal Gel to Children and Adolescents With 22q11.2 Deletion SyndromeOpen-Label, Tolerability and Efficacy Study of ZYN002 Administered as a Transdermal Gel to Children and Adolescents With 22q11.2 Deletion Syndrome22Q Deletion SyndromeDrug: ZYN002Zynerba Pharmaceuticals, Inc.NULLRecruiting4 Years17 YearsAll20Phase 1/Phase 2United States;Australia
3NCT04639960
(ClinicalTrials.gov)
September 29, 20173/11/2020Neuroprotective Effects of Risperdal on Brain and Cognition in 22q11 Deletion SyndromeEffects of Modulation of the Dopaminergic System Using Risperidone on Memory and Executive Processes in Individuals With 22q11.2 Deletion Syndrome22q11.2 Deletion SyndromeDrug: Risperdal;Drug: PlaceboUniversity of Geneva, SwitzerlandNULLRecruiting11 Years25 YearsAll30N/ASwitzerland
4NCT02895906
(ClinicalTrials.gov)
November 28, 201629/8/2016Safety and Efficacy Study of NFC-1 in Subjects Aged 12-17 Years With 22q11.2DS & Associated Neuropsychiatric ConditionsA 5-Week, Multi-center, Open-label Study to Assess the Safety and Efficacy of NFC-1 in Subjects Aged 12-17 Years With 22q11.2 Deletion Syndrome and Commonly Associated Neuropsychiatric Conditions (Anxiety, ADHD, ASD)22q11.2 Deletion SyndromeDrug: NFC-1Aevi Genomic MedicineNULLCompleted12 Years17 YearsAll2Phase 1United States
5NCT04647500
(ClinicalTrials.gov)
August 26, 20163/11/2020Effects of Methylphenidate on Brain and Cognition in 22q11 Deletion SyndromeEffects of Modulation of the Dopaminergic System Using Methylphenidate on Memory and Executive Processes in Individuals With 22q11.2 Deletion Syndrome22q11.2 Deletion SyndromeDrug: ConcertaUniversity of Geneva, SwitzerlandNULLRecruiting8 Years25 YearsAll30N/ASwitzerland