206. 脆弱X症候群 Fragile X syndrome Clinical trials / Disease details


臨床試験数 : 104 薬物数 : 87 - (DrugBank : 32) / 標的遺伝子数 : 54 - 標的パスウェイ数 : 79

  
3 trials found
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1NCT02680379
(ClinicalTrials.gov)
March 201625/1/2016Combined Treatment of Minocycline and Lovastatin to Treat Individuals With Fragile X SyndromeA Pilot Study Exploring the Safety and Synergistic Effect of a Minocycline/Lovastatin Combined Treatment on the Behavior of Individuals With Fragile X Syndrome; Validation of New Biochemical and Neurophysiological Markers (LovaMiX)Fragile X SyndromeDrug: Minocycline, then Minocycline/Lovastatin;Drug: Lovastatin, then Minocycline/LovastatinUniversité de SherbrookeFRAXA Research FoundationCompleted8 Years45 YearsAll22Phase 2Canada
2NCT02998151
(ClinicalTrials.gov)
January 20161/12/2016Neurophysiological and Acute Pharmacological Studies in FXS PatientsNeurophysiological and Acute Pharmacological Studies in FXS PatientsFragile X SyndromeDrug: Acamprosate;Drug: Lovastatin;Drug: Minocycline;Drug: Placebo;Drug: BaclofenChildren's Hospital Medical Center, CincinnatiEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Completed15 Years55 YearsAll29Early Phase 1United States
3NCT02642653
(ClinicalTrials.gov)
January 201621/12/2015Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X SyndromeCombining Lovastatin and a Parent-Implemented Language Intervention in a Multimodal Treatment for Fragile X SyndromeFragile X Syndrome;Genetic DiseasesDrug: Lovastatin;Other: PlaceboUniversity of California, DavisNULLCompleted10 Years17 YearsAll30Phase 4United States