60. 再生不良性貧血 Aplastic anemia Clinical trials / Disease details
臨床試験数 : 235 / 薬物数 : 381 - (DrugBank : 83) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 160
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05018936 (ClinicalTrials.gov) | October 1, 2021 | 19/8/2021 | Efficacy and Safety of Hetrombopag in Non-severe Aplastic Anemia | Efficacy and Safety of Hetrombopag in Non-severe Aplastic Anemia: a Prospective Single Arm Study | Aplastic Anemia;Drug Effect | Drug: Hetrombopag | Peking Union Medical College Hospital | NULL | Not yet recruiting | 18 Years | 75 Years | All | 40 | Phase 2/Phase 3 | China |
| 2 | NCT05088655 (ClinicalTrials.gov) | June 25, 2021 | 12/10/2021 | A Bioequivalence Study of Hetrombopag in Healthy Subjects | Bioequivalence Study of Different Formulations of Hetrombopag Olamine Tablets in Healthy Subjects | Sever Aplastic Anaemia | Drug: Hetrombopag Olamine Tablet | Jiangsu HengRui Medicine Co., Ltd. | NULL | Recruiting | 18 Years | 45 Years | All | 57 | Phase 1 | China |
| 3 | NCT05088642 (ClinicalTrials.gov) | September 28, 2020 | 12/10/2021 | A Trial of Hetrombopag in Healthy and Hepatic Impairment Subjects | A Phase I Clinical Study Evaluating the Pharmacokinetics and Safety of Hetrombopag Olamine Tablets in Subjects With Mild Hepatic Impairment (Child-Pugh Class A), Moderate Hepatic Impairment (Child-Pugh Class B), and Normal Hepatic Function | Sever Aplastic Anaemia | Drug: Hetrombopag Olamine Tablet | Jiangsu HengRui Medicine Co., Ltd. | NULL | Completed | 18 Years | 65 Years | All | 24 | Phase 1 | China |
| 4 | NCT05088174 (ClinicalTrials.gov) | September 3, 2020 | 12/10/2021 | A Trial of Hetrombopag in Healthy Subjects | A Single-Center, Single-Arm, Open-Label, Self-Controlled, Drug-Drug Interaction Study of Hetrombopag Olamine and Ciclosporin in Healthy Subjects | Sever Aplastic Anaemia | Drug: Hetrombopag Olamine Tablet;Ciclosporin Soft Capsule | Jiangsu HengRui Medicine Co., Ltd. | NULL | Completed | 18 Years | 65 Years | All | 26 | Phase 1 | China |
| 5 | NCT04961710 (ClinicalTrials.gov) | September 19, 2019 | 12/7/2021 | Extension Study of Hetrombopag in Severe Aplastic Anemia | Extension Study of Hetrombopag Olamine in Patients With Treatment-naive Severe Aplastic Anemia | Treatment-naive Severe Aplastic Anemia | Drug: Hetrombopag Olamine;Drug: Placebo | Jiangsu HengRui Medicine Co., Ltd. | NULL | Recruiting | 15 Years | 75 Years | All | 180 | Phase 3 | China |
| 6 | NCT03825744 (ClinicalTrials.gov) | March 5, 2019 | 30/1/2019 | Hetrombopag or Placebo in Treatment-Naive Severe Aplastic Anemia | A Phase III Multicenter Randomized Study of Hetrombopag or Placebo in Treatment-Naive Severe Aplastic Anemia | Severe Aplastic Anemia | Drug: Hetrombopag Olamine+Standard Therapy;Drug: Placebo+Standard Therapy | Jiangsu HengRui Medicine Co., Ltd. | NULL | Recruiting | 15 Years | 75 Years | All | 180 | Phase 3 | China |
| 7 | NCT03557099 (ClinicalTrials.gov) | June 20, 2018 | 3/6/2018 | A Study to Evaluate the Safety and Efficacy of Hetrombopag Olamine in Severe Aplastic Anemia (SAA) Patient | A Multicentre, Open-label, Single-arm, Phase II Study to Evaluate the Safety and Efficacy of Hetrombopag Olamine in Patients With Severe Aplastic Anemia | Severe Aplastic Anemia | Drug: Hetrombopag Olamine | Jiangsu HengRui Medicine Co., Ltd. | NULL | Recruiting | 18 Years | N/A | All | 55 | Phase 1/Phase 2 | China |