2. Amyotrophic lateral sclerosis Clinical trials / Disease details

Clinical trials : 624 / Drugs : 611 - (DrugBank : 160) / Drug target genes : 172 - Drug target pathways : 225

6 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01257581 (ClinicalTrials.gov)	March 2011	8/12/2010	Safety and Efficacy Study of Creatine and Tamoxifen in Volunteers With Amyotrophic Lateral Sclerosis (ALS)	Phase 2 Selection Trial of High Dosage Creatine and Two Dosages of Tamoxifen in Amyotrophic Lateral Sclerosis (ALS)	Amyotrophic Lateral Sclerosis	Drug: creatine;Drug: tamoxifen	Nazem Atassi	ALS Therapy Alliance;State University of New York - Upstate Medical University	Completed	18 Years	N/A	All	60	Phase 2	United States
2	NCT00355576 (ClinicalTrials.gov)	July 2006	21/7/2006	Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis	Phase II Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	Drug: Celecoxib;Drug: Creatine;Drug: Minocycline	Columbia University	ALS Association;Pfizer	Completed	21 Years	85 Years	Both	86	Phase 2	United States
3	NCT00069186 (ClinicalTrials.gov)	June 2003	17/9/2003	Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis	A Phase III, Multi-Center, Double-Blind, Placebo Controlled, Randomized Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis (ALS)	Drug: Creatine Monohydrate	The Avicena Group	NULL	Active, not recruiting	21 Years	80 Years	Both	107	Phase 3	United States
4	NCT00070993 (ClinicalTrials.gov)	December 2002	9/10/2003	Creatine for the Treatment of Amyotrophic Lateral Sclerosis	Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	Drug: creatine monohydrate	National Center for Complementary and Integrative Health (NCCIH)	Office of Dietary Supplements (ODS)	Completed	21 Years	80 Years	Both	110	Phase 2	United States
5	NCT00005766 (ClinicalTrials.gov)	May 2000	1/6/2000	Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis		Amyotrophic Lateral Sclerosis	Drug: Creatinine	National Center for Research Resources (NCRR)	NULL	Completed	18 Years	80 Years	Both		Phase 2	United States
6	NCT00005674 (ClinicalTrials.gov)	May 2000	26/5/2000	Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS]		Amyotrophic Lateral Sclerosis	Drug: Creatine	National Center for Research Resources (NCRR)	Muscular Dystrophy Association	Completed	18 Years	80 Years	Both		Phase 2	United States