227. Osler disease Clinical trials / Disease details
Clinical trials : 54 / Drugs : 73 - (DrugBank : 21) / Drug target genes : 23 - Drug target pathways : 136
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2017-001031-39-FR (EUCTR) | 19/05/2017 | 19/06/2020 | BABH Study: Efficacy and safety of bevacizumab on severe bleedings associated with Hemorrhagic Hereditary Telangiectasia (HHT) | BABH Study: Efficacy and safety of bevacizumab on severe bleedings associated with Hemorrhagic Hereditary Telangiectasia (HHT). A National, randomized multicenter phase III study. - BABH | Hemorrhagic Hereditary Telangiectasia MedDRA version: 20.0;Level: LLT;Classification code 10031132;Term: Osler-Weber-Rendu disease;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] | Trade Name: AVASTIN Product Name: BEVACIZUMAB INN or Proposed INN: BEVACIZUMAB | Hospices Civils de Lyon | NULL | Not Recruiting | Female: yes Male: yes | 24 | Phase 3 | France | ||
| 2 | EUCTR2013-004204-19-FR (EUCTR) | 26/02/2014 | 16/06/2015 | Efficacité du bevacizumab en spray nasal pour le traitement des épistaxis dans la maladie de Rendu-Osler | Efficacité du bevacizumab en spray nasal pour le traitement des épistaxis dans la maladie de Rendu-Osler - ALEGORI | Rendu-Osler disease MedDRA version: 18.0;Level: LLT;Classification code 10031132;Term: Osler-Weber-Rendu disease;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] | Trade Name: Avastin Product Name: Avastin INN or Proposed INN: BEVACIZUMAB | Hospices Civils de Lyon | NULL | Not Recruiting | Female: yes Male: yes | France | ||||
| 3 | EUCTR2009-018049-19-AT (EUCTR) | 13/12/2010 | 23/11/2010 | A randomized double blind placebo controlled trial of intranasal submucosal bevacizumab in hereditary hemorrhagic telangiectasia - Bevazizumab in HHT | A randomized double blind placebo controlled trial of intranasal submucosal bevacizumab in hereditary hemorrhagic telangiectasia - Bevazizumab in HHT | epistaxis | Trade Name: AVASTIN 25 mg/ml - Konzentrat zur Herstellung einer Infusionsloesung INN or Proposed INN: BEVACIZUMAB Trade Name: PHYSIOLOGISCHE Kochsalzloesung Fresenius - Infusionsloesung Product Name: PHYSIOLOGISCHE Kochsalzloesung Fresenius - Infusionsloesung Other descriptive name: SODIUM CHLORIDE | Medizinische Universität Wien,Univ.Klinik f.Hals-, Nasen- und Ohrenkrankheiten | NULL | Not Recruiting | Female: yes Male: yes | 30 | Austria | |||
| 4 | EUCTR2008-006755-44-FR (EUCTR) | 15/01/2009 | 17/03/2009 | METAFORE : Maladie de Rendu-Osler : Etude de l’Efficacité et de la tolérance du Bevacizumab utilisé pour le traitement des formes hépatiques sévères. Etude de phase II - METAFORE | METAFORE : Maladie de Rendu-Osler : Etude de l’Efficacité et de la tolérance du Bevacizumab utilisé pour le traitement des formes hépatiques sévères. Etude de phase II - METAFORE | Maladie de Rendu-Osler MedDRA version: 9.1;Level: LLT;Classification code 10031132;Term: Osler-Weber-Rendu disease | Trade Name: AVASTIN Product Name: AVASTIN INN or Proposed INN: BEVACIZUMAB Other descriptive name: SUB16402MIG | HOSPICES CIVILS DE LYON | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | Phase 2 | France | |||
| 5 | EUCTR2010-020545-26-IT (EUCTR) | 09/12/2008 | 10/09/2010 | BEVACIZUMAB, AN ANTI-ANGIOGENIC MONOCLONAL ANTIBODY EFFECTIVE FOR PREVENTION OF HEMORRHAGING IN PATIENTS WITH HEREDITARY HEMORRHAGIC TELANGIECTASIA (HHT): POSSIBLE REGRESSION OF VISCERAL ARTERIOVENOUS MALFORMATIONS - ND | BEVACIZUMAB, AN ANTI-ANGIOGENIC MONOCLONAL ANTIBODY EFFECTIVE FOR PREVENTION OF HEMORRHAGING IN PATIENTS WITH HEREDITARY HEMORRHAGIC TELANGIECTASIA (HHT): POSSIBLE REGRESSION OF VISCERAL ARTERIOVENOUS MALFORMATIONS - ND | HEREDITARY HEMORRHAGIC TELANGIECTASIA (HHT) MedDRA version: 9.1;Level: SOC;Classification code 10005329 | Trade Name: AVASTIN INN or Proposed INN: Bevacizumab Trade Name: AVASTIN INN or Proposed INN: Bevacizumab Trade Name: AVASTIN INN or Proposed INN: Bevacizumab | AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | Italy |