326. Osteopetrosis Clinical trials / Disease details

Clinical trials : 20 / Drugs : 51 - (DrugBank : 14) / Drug target genes : 17 - Drug target pathways : 81

3 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01087398 (ClinicalTrials.gov)	September 2009	13/3/2010	Hematopoietic Stem Cell Transplantation for Malignant Infantile Osteopetrosis	Hematopoietic Stem Cell Transplantation for Malignant Infantile Osteopetrosis	Osteopetrosis	Drug: Busulfan , Cyclophosphamide, Thymoglobulin, Fludarabine (Conditioning regimen);Procedure: Stem Cell Transplantation;Drug: Cyclosporin , Methotrexate (GVHD prophylaxis)	Tehran University of Medical Sciences	NULL	Recruiting	N/A	5 Years	Both	10	Phase 2/Phase 3	Iran, Islamic Republic of
2	NCT00775931 (ClinicalTrials.gov)	August 2008	16/10/2008	Allogeneic Transplantation For Severe Osteopetrosis	Allogeneic Hematopoietic Stem Cell Transplantation For Severe Osteopetrosis	Severe Osteopetrosis	Procedure: umbilical cord blood transplantation;Drug: Campath -1H;Radiation: Total Lymphoid Irradiation;Drug: Cyclophosphamide;Drug: Busulfan;Drug: Fludarabine monophosphate;Procedure: marrow graft transplantation	Masonic Cancer Center, University of Minnesota	NULL	Completed	N/A	45 Years	All	7	Phase 2/Phase 3	United States
3	NCT01019876 (ClinicalTrials.gov)	June 2002	23/11/2009	Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases	Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Selected Non-Malignant Diseases	Bone Marrow Failure;Osteopetrosis;Fanconi Anemia;Severe Combined Immunodeficiency	Drug: Fludarabine;Drug: Cyclophosphamide;Drug: Cyclophosphamide 40;Drug: Cyclophosphamide 30	Columbia University	NULL	Recruiting	N/A	30 Years	Both	50	Phase 2/Phase 3	United States