60. Aplastic anemia Clinical trials / Disease details

Clinical trials : 235 / Drugs : 381 - (DrugBank : 83) / Drug target genes : 44 - Drug target pathways : 160

2 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04558736 (ClinicalTrials.gov)	January 21, 2021	9/9/2020	Haploidentical HCT for Severe Aplastic Anemia	Haploidentical Donor Hematopoietic Cell Transplantation for Patients With Severe Aplastic Anemia	Aplastic Anemia;Bone Marrow Failure Syndrome	Drug: Anti-Thymocyte Globulin (Rabbit);Drug: Fludarabine;Drug: Cyclophosphamide;Drug: Mesna;Drug: G-CSF;Radiation: Total Lymphoid Irradiation (TLI);Device: CliniMACS;Biological: HPC, A Infusion;Biological: CD45RA-depleted DLI	St. Jude Children's Research Hospital	NULL	Recruiting	N/A	21 Years	All	21	Phase 2	United States
2	NCT00987480 (ClinicalTrials.gov)	September 25, 2009	30/9/2009	Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and Fludarabine	A Multicenter Phase II Trial of Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and Fludarabine	Aplastic Anemia;Leukemia;Myelodysplastic Syndrome	Drug: Busulfan , fludarabine, & cyclophosphamide with immunosuppression with ATG and cyclosporine.;Device: CliniMACS device	Memorial Sloan Kettering Cancer Center	Boston Children's Hospital;Children's Hospital Medical Center, Cincinnati;Children's Hospital and Health System Foundation, Wisconsin;Rockefeller University;Fred Hutchinson Cancer Research Center	Completed	N/A	N/A	All	45	Phase 2	United States