PREDNISONE ( DrugBank: Prednisone )


3 diseases
告示番号疾患名(ページ内リンク)臨床試験数
13多発性硬化症/視神経脊髄炎10
51全身性強皮症1
97潰瘍性大腸炎14

13. 多発性硬化症/視神経脊髄炎


臨床試験数 : 3,342 薬物数 : 2,355 - (DrugBank : 406) / 標的遺伝子数 : 269 - 標的パスウェイ数 : 241
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03424733
(ClinicalTrials.gov)
September 25, 201731/1/2018Evaluating the Use of Prednisone to Decrease Pegylated Interferon Beta-1a Side EffectsA Trial of Prednisone and Acetaminophen Versus Acetaminophen Alone in Minimizing Flu-like Symptoms From Pegylated Interferon Beta-1aMultiple SclerosisDrug: Plegridy;Drug: Prednisone;Drug: Tylenol PillHoly Name Medical Center, Inc.BiogenRecruiting18 YearsN/AAll50Phase 4United States
2NCT02784210
(ClinicalTrials.gov)
October 5, 201626/5/2016Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis PlaquesThe Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques: An Investigator-Blinded StudyMultiple SclerosisDrug: Methylprednisolone;Drug: PrednisoneNational Institute of Neurological Disorders and Stroke (NINDS)NULLRecruiting18 YearsN/AAll30Phase 2United States
3NCT02809079
(ClinicalTrials.gov)
January 201612/6/2016Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese PatientsMycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese PatientsNeuromyelitis Optica Spectrum Disorders;Mycophenolate Mofetil;Efficacy and SafetyDrug: Mycophenolate mofetil;Drug: PrednisoneThird Affiliated Hospital, Sun Yat-Sen UniversityZhongshan Ophthalmic Centre, Sun Yat-sen University;Nangfang Hospital, Southern Medical UniversityEnrolling by invitation18 Years65 YearsBoth100Phase 4NULL
4NCT01411514
(ClinicalTrials.gov)
August 201126/5/2011Oral Prednisone Taper Versus Placebo for the Treatment of Acute Relapses in Multiple SclerosisPhase IV Study of Oral Prednisone Taper vs. Placebo Following Intravenous Steroids for the Treatment of Acute Relapses in Multiple Sclerosis Within the Ticino CohortMultiple SclerosisDrug: Prednisone;Drug: PlaceboClaudio GobbiEnte Ospedaliero Cantonale, Ticino, SwitzerlandTerminated18 Years80 YearsBoth27Phase 4Switzerland
5NCT00716066
(ClinicalTrials.gov)
June 200815/7/2008Autologous Peripheral Blood Stem Cell Transplant for Neurologic Autoimmune DiseasesHigh-Dose Immunosuppressive Therapy Using Carmustine, Etoposide, Cytarabine, and Melphalan (BEAM) + Thymoglobulin Followed by Syngeneic or Autologous Hematopoietic Cell Transplantation for Patients With Autoimmune Neurologic DiseasesAutoimmune Disease;Neurologic Autoimmune Disease;Autologous Transplant Autoimmune;Multiple Sclerosis Transplant;MS Stem Cell Transplant;Multiple Sclerosis Stem Cell Transplant;Stiff Person Syndrome;HCT for Neurologic Autoimmune Disorders;CIDP Transplant;Myasthenia Gravis Transplant;Autoimmune Nervous System Disorder;Central Nervous System Vasculitis;Cerebellar Degeneration;Chronic Inflammatory Demyelinating Polyneuropathy;Lambert Eaton Myasthenic Syndrome;Myasthenia Gravis;Neuromyelitis Optica;Opsoclonus Myoclonus Syndrome;Rasmussen Subacute EncephalitisBiological: Anti-Thymocyte Globulin;Procedure: Autologous Hematopoietic Stem Cell Transplantation;Drug: Carmustine;Drug: Cytarabine;Drug: Etoposide;Other: Laboratory Biomarker Analysis;Drug: Melphalan;Procedure: Peripheral Blood Stem Cell Transplantation;Drug: Prednisone;Procedure: Syngeneic Bone Marrow TransplantationFred Hutchinson Cancer Research CenterNULLRecruitingN/A71 YearsAll40Phase 2United States
6NCT00288626
(ClinicalTrials.gov)
July 20067/2/2006High-Dose Immunosuppression and Autologous Transplantation for Multiple Sclerosis (HALT MS) StudyA Phase II Study of High-Dose Immunosuppressive Therapy Using Carmustine, Etoposide, Cytarabine, Melphalan, Thymoglobulin and Autologous CD34+ Hematopoietic Stem Cell Transplant for the Treatment of Poor Prognosis Multiple SclerosisRelapsing-Remitting Multiple SclerosisDrug: Granulocyte-colony stimulating factor (G-CSF) and prednisone;Drug: Carmustine, etoposide, cytarabine, and melphalan (BEAM);Procedure: Autologous hematopoietic stem cell transplantNational Institute of Allergy and Infectious Diseases (NIAID)Immune Tolerance Network (ITN)Completed18 Years60 YearsAll25Phase 2United States
7NCT00203047
(ClinicalTrials.gov)
January 200513/9/2005Assessment Study of Steroid Effect in Relapsing Multiple Sclerosis Subjects Treated With Glatiramer AcetateA Multi-Centered, Randomized, Double-Blind, Placebo Controlled Study Assessing the Add-on Effect of Oral Steroids in Relapsing Remitting Multiple Sclerosis Subjects Treated With Glatiramer Acetate (GA)Relapsing Remitting Multiple SclerosisDrug: Glatiramer Acetate;Drug: Placebo;Drug: PrednisoneTeva Pharmaceutical IndustriesNULLTerminated18 Years55 YearsAll414Phase 4Canada;United States
8NCT00014755
(ClinicalTrials.gov)
December 199710/4/2001Phase I Pilot Study of Total-Body Irradiation, Anti-Thymocyte Globulin and Cyclophosphamide Followed By Syngeneic or Autologous Peripheral Blood Stem Cell Transplantation in Patients With Multiple SclerosisMultiple SclerosisDrug: anti-thymocyte globulin;Drug: cyclophosphamide;Drug: filgrastim;Drug: prednisone;Procedure: peripheral blood stem cell transplantation;Procedure: irradiationFred Hutchinson Cancer Research CenterNULLCompleted18 Years60 YearsBoth35Phase 1United States
9NCT00000146
(ClinicalTrials.gov)
July 198823/9/1999Optic Neuritis Treatment Trial (ONTT)Multiple Sclerosis;Optic NeuritisDrug: Methylprednisolone;Drug: PrednisoneNational Eye Institute (NEI)NULLActive, not recruiting18 Years46 YearsBothPhase 3United States
10NCT00000147
(ClinicalTrials.gov)
July 198823/9/1999Longitudinal Optic Neuritis Study (LONS)Multiple Sclerosis;Optic NeuritisDrug: Methylprednisolone;Drug: PrednisoneNational Eye Institute (NEI)NULLActive, not recruiting18 Years46 YearsBothN/AUnited States

51. 全身性強皮症


臨床試験数 : 523 薬物数 : 608 - (DrugBank : 156) / 標的遺伝子数 : 114 - 標的パスウェイ数 : 215
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01086540
(ClinicalTrials.gov)
June 24, 201111/3/2010Rituximab for Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)A Randomized, Double-Blind, Placebo-Controlled, Phase II Multicenter Trial of a Monoclonal Antibody to CD20 (Rituximab) for the Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)Systemic Sclerosis-Associated PAHBiological: Rituximab;Other: Placebo;Diagnostic Test: CMRI;Drug: prednisone;Drug: methylprednisolone;Drug: diphenhydramine;Drug: acetaminophenNational Institute of Allergy and Infectious Diseases (NIAID)Autoimmunity Centers of Excellence;Rho Federal Systems Division, Inc.Completed18 Years75 YearsAll57Phase 2United States

97. 潰瘍性大腸炎


臨床試験数 : 2,527 薬物数 : 1,465 - (DrugBank : 259) / 標的遺伝子数 : 144 - 標的パスウェイ数 : 202
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04882683
(ClinicalTrials.gov)
June 1, 20216/5/2021Clinical Study of Cord Blood Mononuclear Cells on Treatment of Hormone-resistant or Hormone-dependent Ulcerative ColitisClinical Study of Cord Blood Mononuclear Cells on Treatment of Hormone-resistant or Hormone-dependent Ulcerative ColitisUlcerative ColitisDrug: Prednisone;Drug: Azathioprine;Drug: Adalimumab;Biological: umbilical cord blood mononuclear cellsShandong Qilu Stem Cells Engineering Co., Ltd.NULLRecruiting18 Years65 YearsAll50N/AChina
2ChiCTR2100046284
2021-05-062021-05-12Clinical study of cord blood mononuclear cells on treatment of hormone-resistant or hormone-dependent ulcerative colitis Clinical study of cord blood mononuclear cells on treatment of hormone-resistant or hormone-dependent ulcerative colitis ulcerative colitisControl group:Prednisone+Azathioprine/Adalimumab;Test group:Prednisone+Azathioprine/Adalimumab+umbilical cord blood mononuclear cells;The Second Affiliated Hospital of Shandong University of Traditional Chinese MedicineNULLRecruiting1865BothControl group:25;Test group:25;China
3EUCTR2020-003420-16-IT
(EUCTR)
29/01/202102/08/2021A study comparing two different therapeutic approaches in the treatment of moderate to severe ulcerative colitis.SPRINT_”AN OPEN-LABEL, MULTICENTER STUDY TO EVALUATE STEP-UP VS TOP-DOWN TREATMENT ALGORITHMS IN MODERATE TO SEVERE ULCERATIVE COLITIS.” - SPRINT Moderate to severe ulcerative colitis.
MedDRA version: 20.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856
MedDRA version: 20.1;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Trade Name: Amgevita
Product Name: Adalimumab
Product Code: [n.d.]
INN or Proposed INN: ADALIMUMAB
Product Name: Azatioprina
Product Code: [n.d.]
INN or Proposed INN: AZATIOPRINA
Product Name: Prednisone
Product Code: [n.d.]
INN or Proposed INN: PREDNISONE
INN or Proposed INN: PREDNISONE
IRCCS ISTITUTO CLINICO HUMANITASNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
350Phase 4Portugal;France;Spain;Belgium;Austria;Germany;United Kingdom;Switzerland;Italy;Sweden
4ChiCTR1900024591
2019-07-222019-07-18Clinical evaluation for traditional Chinese medicine in the treatment of severe active ulcerative colitisClinical evaluation for traditional Chinese medicine in the treatment of severe active ulcerative colitis Ulcerative colitisTCM Group:Prednisone+New Wumeiwan Formula;Convenience medicine Group:Prednisone+Mesalazine Enteric-coated tablets (Salofalk);Combined Group:Prednisone+New Wumeiwan Formula+Mesalazine Enteric-coated tablets(Salofalk);Peking University First HospitalNULLPending1865BothTCM Group:40;Convenience medicine Group:40;Combined Group:40;China
5NCT03804931
(ClinicalTrials.gov)
January 20, 20196/1/2019Fecal Microbiota Transplantation for Ulcerative ColitisEfficacy and Safety of Fecal Microbiota Transplantation for Ulcerative ColitisUlcerative Colitis;Fecal Microbiota TransplantationProcedure: Fecal microbiota transplantation;Procedure: Infusion of Saline;Drug: 5-Aminosalicylic acid(5-ASA) and/or PrednisoneGuangzhou First People's HospitalNULLRecruiting18 Years65 YearsAll120Phase 2/Phase 3China
6NCT02921555
(ClinicalTrials.gov)
October 11, 201822/9/2016Endovenous Corticosteroid Pulses in Moderate Ulcerative ColitisEfficacy of High-dose Corticosteroid Pulses Added to Conventional Oral Corticosteroid Course for Moderate Flares of Ulcerative Colitis.Ulcerative ColitisDrug: Methylprednisolone;Drug: PrednisoneGrupo Espanol de Trabajo en Enfermedad de Crohn y Colitis UlcerosaNULLRecruiting18 YearsN/AAll148Phase 4Spain
7NCT02910245
(ClinicalTrials.gov)
November 20169/9/2016Mercaptopurine Therapy in Ulcerative ColitisEfficacy of Optimized Thiopurine Therapy in Ulcerative Colitis (OPTIC)Colitis, UlcerativeDrug: Mercaptopurine (Purinethol);Drug: Placebo;Drug: Mesalamine;Drug: PrednisoneAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)ZonMw: The Netherlands Organisation for Health Research and DevelopmentRecruiting18 Years80 YearsAll136Phase 3Netherlands
8ChiCTR-ICR-15007188
2015-10-092015-10-09Percutaneous endoscopic mini-colostomy anddrug delivery system for the treatment of ulcerative colitis: A randomized, controlled clinical trialPercutaneous endoscopic mini-colostomy anddrug delivery system for the treatment of ulcerative colitis: A randomized, controlled clinical trial Ulcerative colitisPercutaneous endoscopic mini-colostomy group:Oral steroids (prednisone 1mg.kg-1d-1) +Percutaneous endoscopic mini-colostomy andsubsequent drug delivery (mesalazine 3g / d);Control Group:Oral steroids (prednisone 1mg.kg-1d-1) andmesalazine 3g / d;Southern Medical University, Nanfang Hospital, Department of GastroenterologyNULLRecruitingBothPercutaneous endoscopic mini-colostomy group:21;Control Group:21;China
9EUCTR2007-003815-30-PT
(EUCTR)
31/07/200905/03/2009An Open Randomized Multicenter Clinical Investigation to Compare the Efficacy and Safety of Prednisone plus Adacolumn® GMA Apheresis versus Prednisone Alone in the Treatment of Patients with Mild or Moderately Active Steroid Dependent Ulcerative ColitisAn Open Randomized Multicenter Clinical Investigation to Compare the Efficacy and Safety of Prednisone plus Adacolumn® GMA Apheresis versus Prednisone Alone in the Treatment of Patients with Mild or Moderately Active Steroid Dependent Ulcerative Colitis Mild or Moderately Active Steroid Dependent Ulcerative Colitis
MedDRA version: 14.0;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 10017947 - Gastrointestinal disorders
Trade Name: Dacortin
Product Name: prednisone
INN or Proposed INN: Prednisone
INN or Proposed INN: Prednisone
Trade Name: Dacortin
Product Name: prednisone
Product Code: H02AB
INN or Proposed INN: PREDNISONE
INN or Proposed INN: PREDNISONE
GETECCU (Grupo Español de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa)NULLNot RecruitingFemale: yes
Male: yes
Portugal;Spain
10EUCTR2006-004230-32-BE
(EUCTR)
21/12/200704/12/2007Efficacy and safety of Beclomethasone dipropionate, gastro-resistant, prolonged release tablets (CHF1514) compared to oral prednisone, in a 8-week treatment period, in patients with active ulcerative colitis. An international, multicentre, randomized, double blind, parallel group study. - Beta studyEfficacy and safety of Beclomethasone dipropionate, gastro-resistant, prolonged release tablets (CHF1514) compared to oral prednisone, in a 8-week treatment period, in patients with active ulcerative colitis. An international, multicentre, randomized, double blind, parallel group study. - Beta study Ulcerative colitis extending proximally beyond the rectum.
MedDRA version: 9.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis
Trade Name: Clipper 30 cpr 5mg R.M.
INN or Proposed INN: BECLOMETASONE DIPROPIONATE
Trade Name: Deltacortene 20 cpr 5mg
INN or Proposed INN: PREDNISONE
Trade Name: Deltacortene 10 cpr 25mg
INN or Proposed INN: PREDNISONE
CHIESI Farmaceutici S.p.A.NULLNot RecruitingFemale: yes
Male: yes
300Belgium;Spain;Italy;Poland
11EUCTR2006-004230-32-PL
(EUCTR)
07/12/200705/09/2007EFFICACY AND SAFETY OF BECLOMETHASONE DIPROPIONATE GASTRO-RESISTANT, PROLONGED RELEASE TABLETS (CHF 1514) COMPARED WITH ORAL PREDNISONE, IN A 8-WEEK TREATMENT PERIOD, IN PATIENTS WITH ACTIVE ULCERATIVE COLITIS. AN INTERNATIONAL, MUTICENTRE, RANDOMISED, DOUBLE BLIND, PARALLEL GROUP STUDY - Beta study EFFICACY AND SAFETY OF BECLOMETHASONE DIPROPIONATE GASTRO-RESISTANT, PROLONGED RELEASE TABLETS (CHF 1514) COMPARED WITH ORAL PREDNISONE, IN A 8-WEEK TREATMENT PERIOD, IN PATIENTS WITH ACTIVE ULCERATIVE COLITIS. AN INTERNATIONAL, MUTICENTRE, RANDOMISED, DOUBLE BLIND, PARALLEL GROUP STUDY - Beta study Ulcerative Colitis extending proximally beyond the rectum with bleeding, verified by endoscopic examination
MedDRA version: 9.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis
Trade Name: Clipper
INN or Proposed INN: Beclomethasone diproprionate
Trade Name: Deltacortene
INN or Proposed INN: Prednisone
Trade Name: Deltacortene
INN or Proposed INN: Prednisone
Chiesi Farmaceutici SpANULLNot RecruitingFemale: yes
Male: yes
300Phase 3Belgium;Spain;Poland;Italy
12EUCTR2007-003815-30-ES
(EUCTR)
27/11/200724/10/2007Estudio abierto, randomizado, multicéntrico para comparar la eficacia y la seguridad de la prednisona y granulocitoféresis con Adacolumn® versus la prednisona sola en el tratamiento de pacientes con colitis ulcerosa activa corticodependiente leve a moderada.Estudio abierto, randomizado, multicéntrico para comparar la eficacia y la seguridad de la prednisona y granulocitoféresis con Adacolumn® versus la prednisona sola en el tratamiento de pacientes con colitis ulcerosa activa corticodependiente leve a moderada. Colitis ulcerosa corticodependiente leve o moderada
MedDRA version: 9.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis
Trade Name: DACORTIN
Product Name: PREDNISONE
INN or Proposed INN: PREDNISONE
Other descriptive name: N/A
GETECCU (Grupo Español de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa)NULLNot RecruitingFemale: yes
Male: yes
Portugal;Spain
13EUCTR2006-004230-32-ES
(EUCTR)
22/08/200726/09/2007EFICACIA Y SEGURIDAD DE COMPRIMIDOS DE BECLOMETASONA DIPROPIONATO (CHF1514) GASTRORRESISTENTES DE LIBERACIÓN PROLONGADA, FRENTE A PREDNISONA ORAL, DURANTE UN PERIODO DE TRATAMIENTO DE 8 SEMANAS EN PACIENTES CON COLITIS ULCEROSA ACTIVA. ESTUDIO INTERNACIONAL, MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO DE GRUPOS PARALELOS. - Estudio BETAEFICACIA Y SEGURIDAD DE COMPRIMIDOS DE BECLOMETASONA DIPROPIONATO (CHF1514) GASTRORRESISTENTES DE LIBERACIÓN PROLONGADA, FRENTE A PREDNISONA ORAL, DURANTE UN PERIODO DE TRATAMIENTO DE 8 SEMANAS EN PACIENTES CON COLITIS ULCEROSA ACTIVA. ESTUDIO INTERNACIONAL, MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO DE GRUPOS PARALELOS. - Estudio BETA Colitis ulcerosa activa, extendiéndose en sentido proximal más allá del recto.
MedDRA version: 9.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis
Trade Name: Clipper
INN or Proposed INN: BECLOMETASONE DIPROPIONATE
Trade Name: Deltacortene
INN or Proposed INN: PREDNISONE
Trade Name: Deltacortene
INN or Proposed INN: PREDNISONE
Chiesi Farmaceutici SpANULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
300Belgium;Spain;Italy;Poland
14EUCTR2006-004230-32-IT
(EUCTR)
06/06/200712/11/2007Efficacy and safety of beclometasone dipropionate (BDP) gastro-resistant prolonged release tablets (CHF1514) compared to oral steroid (prednisone) in an 8-week treatment period in patients with active moderate ulcerative colitis. A multicentre, randomised, controlled, double blind, parallel group study. Beta study - BETAEfficacy and safety of beclometasone dipropionate (BDP) gastro-resistant prolonged release tablets (CHF1514) compared to oral steroid (prednisone) in an 8-week treatment period in patients with active moderate ulcerative colitis. A multicentre, randomised, controlled, double blind, parallel group study. Beta study - BETA Mild moderate active ulcerative colitis
MedDRA version: 9.1;Level: LLT;Classification code 10009900;Term: Colitis ulcerative
Trade Name: CLIPPER*30CPR 5MG R.M.
INN or Proposed INN: Beclometasone
Trade Name: DELTACORTENE*20CPR 5MG
INN or Proposed INN: Prednisone
Trade Name: DELTACORTENE FORTE*10CPR 25MG
INN or Proposed INN: Prednisone
CHIESINULLNot RecruitingFemale: yes
Male: yes
300Belgium;Spain;Italy;Poland