Naltrexone ( DrugBank: Naltrexone )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
96	クローン病	4
226	間質性膀胱炎（ハンナ型）	2

96. クローン病

臨床試験数 : 2,400 / 薬物数 : 1,391 - (DrugBank : 267) / 標的遺伝子数 : 170 - 標的パスウェイ数 : 215

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2019-000852-32-NL (EUCTR)	30/01/2020	08/10/2019	A preliminary study of Low Dose Naltrexone for the induction of remission in patients with mild to moderate Crohn’s Disease that failed conventional treatment: The LDN Crohn study.	A preliminary study of Low Dose Naltrexone for the induction of remission in patients with mild to moderate Crohn’s Disease that failed conventional treatment: The LDN Crohn study. - The LDN Crohn study	Inflammatory Bowel Disease, Crohn's disease;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Product Name: Naltrexone hydrochloride	ErasmusMC	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	122	Phase 2	Netherlands
2	NCT01810185 (ClinicalTrials.gov)	March 2013	11/3/2013	Low Dose Naltrexone in Symptomatic Inflammatory Bowel Disease	Low Dose Naltrexone in Symptomatic Inflammatory Bowel Disease	Inflammatory Bowel Disease;Crohn's Disease;Ulcerative Colitis	Drug: Low dose naltrexone;Drug: Placebo	Santa Barbara Cottage Hospital	NULL	Withdrawn	18 Years	N/A	Both	0	Phase 2	United States
3	NCT00715117 (ClinicalTrials.gov)	July 2008	14/7/2008	The Efficacy of Low Dose Naltrexone Therapy in Children With Crohn's Disease	The Efficacy of Low Dose Naltrexone Therapy in Children With Crohn's Disease	Crohn's Disease	Drug: Naltrexone;Other: Placebo, sugar pill	Milton S. Hershey Medical Center	NULL	Completed	6 Years	17 Years	All	14	Phase 2	United States
4	NCT00663117 (ClinicalTrials.gov)	September 2006	18/4/2008	The Effects of Naltrexone on Active Crohn's Disease	The Effects of Naltrexone in Active Crohn's Disease	Inflammation;Crohn's Disease	Drug: Naltrexone-HCl;Drug: Placebo	Milton S. Hershey Medical Center	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);The Broad Foundation	Completed	18 Years	75 Years	All	40	Phase 2	United States

226. 間質性膀胱炎（ハンナ型）

臨床試験数 : 143 / 薬物数 : 171 - (DrugBank : 56) / 標的遺伝子数 : 64 - 標的パスウェイ数 : 145

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04313972 (ClinicalTrials.gov)	September 7, 2021	16/3/2020	IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone	IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone, the Effect of Low Dose Naltrexone on Symptoms and Pain of Patients With Interstitial Cystitis/Painful Bladder Syndrome a Randomized Placebo-controlled Prospective Trial	Interstitial Cystitis;Painful Bladder Syndrome;Bladder Pain Syndrome;Low Dose Naltrexone;Low-dose Naltrexone;Naltrexone	Drug: low-dose naltrexone;Drug: Placebo oral tablet	NorthShore University HealthSystem	NULL	Recruiting	18 Years	110 Years	Female	44	Phase 4	United States
2	NCT04450316 (ClinicalTrials.gov)	October 8, 2020	24/6/2020	Low-dose Naltrexone for Bladder Pain Syndrome	Low-dose Naltrexone for Bladder Pain Syndrome: A Randomized Placebo-controlled Prospective Pilot Trial	Bladder Pain Syndrome;Interstitial Cystitis	Drug: Naltrexone;Drug: Placebo	Stanford University	NULL	Recruiting	18 Years	N/A	All	40	Phase 2	United States