Autologous mesenchymal stromal cell ( DrugBank: - )


2 diseases
告示番号疾患名(ページ内リンク)臨床試験数
96クローン病5
298遺伝性膵炎2

96. クローン病


臨床試験数 : 2,400 薬物数 : 1,391 - (DrugBank : 267) / 標的遺伝子数 : 170 - 標的パスウェイ数 : 215
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03449069
(ClinicalTrials.gov)
July 23, 201822/2/2018Pediatric MSC-AFP Sub-study for Crohn's FistulaA Phase I Study of Autologous Mesenchymal Stromal Cell Coated Fistula Plug in Patients With Fistulizing Crohn's Disease: Pediatric Sub-studyFistula in Ano;Crohn DiseaseDrug: MSC-AFPMayo ClinicNULLRecruiting12 Years17 YearsAll5Phase 1United States
2NCT03220243
(ClinicalTrials.gov)
October 19, 201714/7/2017Stem Cell Coated Fistula Plug in Patients With Crohn's RVFA Phase I Study of Autologous Mesenchymal Stromal Cell Coated Fistula Plug in Patients With Rectovaginal Fistulizing Crohn's DiseaseFistula Vagina;Crohn DiseaseDrug: MSC-AFPMayo ClinicNULLCompleted18 Years65 YearsFemale5Phase 1United States
3NCT03014219
(ClinicalTrials.gov)
July 20174/1/2017Phase 1 Crohn's Pediatric Sub-study of MSC AFPA Phase I Study of Autologous Mesenchymal Stromal Cell Coated Fistula Plug in Patients With Fistulizing Crohn's Disease: Pediatric Sub-studyPerianal FistulaDrug: Only 1 arm: treatment with MSC-AFPWilliam A. Faubion, M.D.NULLWithdrawn12 Years17 YearsAll0Phase 1United States
4NCT01915927
(ClinicalTrials.gov)
July 201331/7/2013Stem Cell Fistula Plug in Perianal Crohn's DiseaseA Phase 1 Study of Autologous Mesenchymal Stromal Cell Coated Fistula Plug in Patients With Fistulizing Crohn's Disease.Perianal Crohn's DiseaseDrug: MSC-AFPWilliam A. Faubion, M.D.NULLCompleted18 Years65 YearsAll20Phase 1United States
5NCT01659762
(ClinicalTrials.gov)
July 20126/8/2012A Phase I Study Evaluating Autologous Bone Marrow Derived Mesenchymal Stromal for Crohn's Disease.A Phase I Study Evaluating Safety and Tolerability of Autologous Bone Marrow Derived Mesenchymal Stromal (MSC) Cells in Adults With Moderate to Severe Crohn's Disease.Crohn's DiseaseBiological: autologous mesenchymal stromal cellEmory UniversityAtlanta Clinical and Translational Science Institute;Atlanta Clinical and Translational Science InstituteCompleted18 Years65 YearsBoth16Phase 1United States

298. 遺伝性膵炎


臨床試験数 : 98 薬物数 : 180 - (DrugBank : 57) / 標的遺伝子数 : 53 - 標的パスウェイ数 : 142
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT05095532
(ClinicalTrials.gov)
December 1, 202111/10/2021Autologous Mesenchymal Stromal Cells and Islet Co-transplantation in TP-IATAutologous Mesenchymal Stromal Cells and Islet Co-transplantation to Enhance Islet Survival and Function in Chronic Pancreatitis Patients Undergo Total Pancreatectomy and Islet AutotransplantationChronic Pancreatitis;Mesenchymal Stem CellsBiological: Bone marrow-derived mesenchymal stem cells;Other: PlaceboMedical University of South CarolinaNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Recruiting18 YearsN/AAll42Phase 1United States
2NCT02384018
(ClinicalTrials.gov)
December 201416/12/2014Mesenchymal Stem Cell and Islet Co-transplantationA Phase I Study Evaluating Safety and Tolerability of Autologous Bone Marrow-derived Mesenchymal Stromal Cells in Chronic Pancreatitis Patients Who Undergo Total Pancreatectomy and Islet Autotransplantation.Chronic Pancreatitis;DiabetesBiological: autologous mesenchymal stromal cellMedical University of South CarolinaNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Active, not recruiting18 Years69 YearsAll24Phase 1United States