Drug（薬物リスト） DrugBank | All Description Patterns💬 Info on mouse-over

No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	Any other approved antiepileptic drug	-	-	-	-	1件: 144 💬
2	Cannabidiol	Cannabidiol	1件: D10915 💬	2件: CNR1, CNR2 💬	4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis	17件:  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 226, 271 💬
3	Cannabidiol (cbd)	Cannabidiol	1件: D10915 💬	2件: CNR1, CNR2 💬	4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis	6件:  6 , 140, 144, 145, 156, 158 💬
4	Cannabidiol oral solution	Cannabidiol	1件: D10915 💬	2件: CNR1, CNR2 💬	4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis	4件: 140, 144, 145, 193 💬
5	Carisbamate	Carisbamate	1件: D06573 💬	-	-	1件: 144 💬
6	Cbd	-	-	-	-	11件:  2 ,  6 ,  8 , 13, 46, 140, 144, 145, 156, 158, 206 💬
7	Cbd - oral solution, is known as epidiolex, and is the approved name in the usa.	-	-	-	-	3件: 140, 144, 158 💬
8	Clobazam	Clobazam	1件: D01253 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	2件: 140, 144 💬
9	Clobazam high dose	Clobazam	1件: D01253 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	1件: 144 💬
10	Clobazam low dose	Clobazam	1件: D01253 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	1件: 144 💬
11	Clobazam medium dose	Clobazam	1件: D01253 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	1件: 144 💬
12	Clobazam pheur	Clobazam	1件: D01253 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	1件: 144 💬
13	Clobazam tablets	Clobazam	1件: D01253 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	1件: 144 💬
14	Clobazam tablets 10mg	Clobazam	1件: D01253 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	1件: 144 💬
15	Clobazam tablets 20mg	Clobazam	1件: D01253 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	1件: 144 💬
16	Clobazam tablets 5mg	Clobazam	1件: D01253 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction	1件: 144 💬
17	E2007	-	-	-	-	2件:  6 , 144 💬
18	E2080	-	-	-	-	1件: 144 💬
19	Ezogabine	Ezogabine	1件: D09569 💬	5件: KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬	6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection	2件:  2 , 144 💬
20	Ezogabine (us only)	Ezogabine	1件: D09569 💬	5件: KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬	6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection	1件: 144 💬
21	Ezogabine/retigabine	Ezogabine	1件: D09569 💬	5件: KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬	6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection	1件: 144 💬
22	Fenfluramine	Fenfluramine	1件: D07945 💬	4件: HTR2A, HTR2B, HTR2C, SLC6A4 💬	6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	3件: 140, 144, 145 💬
23	Fenfluramine hcl, dl-fenfluramine, (±)-fenfluramine	Fenfluramine	1件: D07945 💬	4件: HTR2A, HTR2B, HTR2C, SLC6A4 💬	6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	1件: 144 💬
24	Fenfluramine hydrochloride	Fenfluramine	1件: D07945 💬	4件: HTR2A, HTR2B, HTR2C, SLC6A4 💬	6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	2件: 140, 144 💬
25	Fenfluramine hydrochloride (colorless)	Fenfluramine	1件: D07945 💬	4件: HTR2A, HTR2B, HTR2C, SLC6A4 💬	6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	2件: 140, 144 💬
26	Fycompa	-	-	-	-	2件:  2 , 144 💬
27	Gw582892	-	-	-	-	1件: 144 💬
28	Gwp42003-p	-	-	-	-	5件: 140, 144, 145, 156, 158 💬
29	Gwp42003-p 20 mg/kg/day dose	-	-	-	-	2件: 140, 144 💬
30	Inovelon	-	-	-	-	1件: 144 💬
31	Investigators choice of approved aed	-	-	-	-	1件: 144 💬
32	Investigators choice of approved aeds	-	-	-	-	1件: 144 💬
33	Lamictal	-	-	-	-	1件: 144 💬
34	Lamotrigine	Lamotrigine	1件: D00354 💬	5件: SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	5件: 13, 34, 38, 114, 144 💬
35	Melatonin	Melatonin	1件: D08170 💬	2件: MTNR1A, MTNR1B 💬	2件: Circadian entrainment, Neuroactive ligand-receptor interaction	11件:  6 ,  8 , 13, 46, 49, 90, 97, 144, 145, 149, 202 💬
36	Perampanel	Perampanel	1件: D08964 💬	4件: GRIA1, GRIA2, GRIA3, GRIA4 💬	16件: Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway	3件:  2 ,  6 , 144 💬
37	Placebo	-	-	-	-	26件:  3 ,  5 ,  6 , 13, 14, 37, 40, 46, 49, 50, 51, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276 💬
38	Potiga	-	-	-	-	1件: 144 💬
39	Procedure: 12-lead ecg	-	-	-	-	2件: 140, 144 💬
40	Retigabine	Ezogabine	1件: D09569 💬	5件: KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬	6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection	2件:  2 , 144 💬
41	Retigabine/ezogabine	Ezogabine	1件: D09569 💬	5件: KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬	6件: Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection	1件: 144 💬
42	Rufinamide	Rufinamide	1件: D05775 💬	5件: SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	1件: 144 💬
43	Rufinamide (e2080)	Rufinamide	1件: D05775 💬	5件: SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	1件: 144 💬
44	Rufinamide oral suspension	Rufinamide	1件: D05775 💬	5件: SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction	1件: 144 💬
45	Sodio valproato	-	-	-	-	1件: 144 💬
46	Tak-935	-	-	-	-	2件: 140, 144 💬
47	Topimarate	-	-	-	-	1件: 144 💬
48	Topimarato	-	-	-	-	1件: 144 💬
49	Topiramate	Topiramate	1件: D00537 💬	36件: CA2, CA4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	52件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	5件:  6 , 140, 144, 156, 193 💬
50	Turmeric	Turmeric	-	-	-	4件: 140, 144, 158, 299 💬
51	Zx008	-	-	-	-	2件: 140, 144 💬
52	Zx008 (fenfluramine hydrochloride)	Fenfluramine	1件: D07945 💬	4件: HTR2A, HTR2B, HTR2C, SLC6A4 💬	6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle	2件: 140, 144 💬
53	Zx008 0.2 and 0.8 mg/kg/day	-	-	-	-	2件: 140, 144 💬
54	Zx008 0.2 or 0.8 mg/kg/day	-	-	-	-	1件: 144 💬

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