Drug（薬物リスト） DrugBank | All Description Patterns💬 Info on mouse-over

No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	Bosentan	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
2	Bosentan (tracleer)	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 51 💬
3	Bosentan 125 mg	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 51 💬
4	Bosentan 62.5 mg	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 51 💬
5	Bosentan administration	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
6	Bosentan and sildenafil	Bosentan	4件: D01227, D02229, D07538, D08514 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
7	Bosentan group	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 51 💬
8	Bosentan monohidrato	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
9	Bosentan monohydrat	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
10	Bosentan monohydrate	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	4件: 51, 84, 86, 88 💬
11	Bosentan mylan	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 41 💬
12	Bosentan, ambrisentan	Ambrisentan	3件: D01227, D07077, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
13	Device: nirs after bosentan administration	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 13 💬
14	Device: tcd after bosentan administration	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 13 💬
15	Duo-therapy with sildenafil + bosentan	Bosentan	4件: D01227, D02229, D07538, D08514 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
16	Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan)	Bosentan	6件: D01227, D02008, D02229, D07538, D08514, D10135 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
17	Sildenafil 20mg and bosentan 62.5mg	Bosentan	4件: D01227, D02229, D07538, D08514 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	2件: 51, 86 💬
18	Sildenafil singly or in association with bosentan	Bosentan	4件: D01227, D02229, D07538, D08514 💬	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬