Drug（薬物リスト） DrugBank | All Description Patterns💬 Info on mouse-over

No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	100 mg elx/50 mg tez/75 mg iva fixed dose combination	-	-	-	-	1件: 299 💬
2	50 mg elx/25 mg tez/37.5 mg iva fixed dose combination	-	-	-	-	1件: 299 💬
3	A fixed-dose combination of 95 mg clarithromycin, 45 mg rifabutin, and 10 mg clofazimine	Clarithromycin	3件: D00276, D00278, D00424 💬	-	-	1件: 96 💬
4	Calcium and vitamin d combination	Calcium	-	-	-	1件: 13 💬
5	Combination	-	-	-	-	1件: 46 💬
6	Combination antiviral therapy	-	-	-	-	1件: 93 💬
7	Combination fish oil and borage seed oil	Fish oil	-	-	-	1件: 46 💬
8	Combination injection of epo and g-csf	Filgrastim	1件: D03235 💬	1件: CSF3R 💬	5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer	1件:  6  💬
9	Combination of a single dose anti-cd20 antibody and bortezomib	Bortezomib	1件: D03150 💬	1件: PSMB5 💬	8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia	1件: 61 💬
10	Combination of fish oil and colesevelam	Colesevelam	2件: D03582, D07743 💬	-	-	1件: 260 💬
11	Combination of minocycline and mtx or mtx alone	Minocycline	2件: D00850, D05045 💬	-	-	1件: 46 💬
12	Combination of protein a immunoadsorption, rituximab, dexamethasone plus azathioprine	Azathioprine	12件: D00238, D00292, D00975, D01510, D01615, D01632, D01948, D02174, D02591, D02592, D02994, D03033 💬	2件: MS4A1, NR3C1 💬	2件: Hematopoietic cell lineage, Neuroactive ligand-receptor interaction	1件: 35 💬
13	Combination of thrombopoietin mimetic and cyclosporin a	Cyclosporine	1件: D00184 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	32件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	1件: 60 💬
14	Combination oral budesonide and rectal hydrocortisone	Budesonide	2件: D00088, D00246 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	1件: 97 💬
15	Combination product (natpara) and drug or supplements [disease and drug registry]	-	-	-	-	1件: 235 💬
16	Combination product: device: axially oscillating sphere dry powder inhaler (aos dpi)	-	-	-	-	1件: 86 💬
17	Combination product: active treatment with dual therapy	-	-	-	-	1件:  2  💬
18	Combination product: beclomethasone dipropionate in addition to mc-evoo	Beclomethasone dipropionate	2件: D00689, D07495 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	1件: 97 💬
19	Combination product: beclomethasone dipropionate in addition to refined oil	Beclomethasone dipropionate	2件: D00689, D07495 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	1件: 97 💬
20	Combination product: belimumab	Belimumab	1件: D03068 💬	1件: TNFSF13B 💬	4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis	1件: 49 💬
21	Combination product: goldic serum	-	-	-	-	1件: 70 💬
22	Combination product: hyperbaric oxygen therapy-	Oxygen	1件: D00003 💬	-	-	1件: 226 💬
23	Combination product: implantable system for remodulin (treprostinil)	Treprostinil	1件: D06213 💬	1件: PTGIR 💬	3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction	1件: 86 💬
24	Combination product: l-dopa 140 mg	Levodopa	1件: D00059 💬	5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬	11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	1件:  6  💬
25	Combination product: l-dopa 35 mg	Levodopa	1件: D00059 💬	5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬	11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	1件:  6  💬
26	Combination product: l-dopa 70mg	Levodopa	1件: D00059 💬	5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬	11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway	1件:  6  💬
27	Combination product: l-dopa 70mg/carbidopa 7mg	Carbidopa	2件: D00059, D00558 💬	6件: DDC, DRD1, DRD2, DRD3, DRD4, DRD5 💬	16件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway	1件:  6  💬
28	Combination product: mavrilimumab	Mavrilimumab	1件: D09930 💬	1件: CSF2RA 💬	4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer	1件: 41 💬
29	Combination product: methotrexate	Methotrexate	2件: D00142, D02115 💬	2件: DHFR, DHFR2 💬	5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	1件: 46 💬
30	Combination product: nd0612 solution for sc infusion	-	-	-	-	1件:  6  💬
31	Combination product: ofatumumab with ai	Ofatumumab	1件: D09314 💬	1件: MS4A1 💬	1件: Hematopoietic cell lineage	1件: 13 💬
32	Combination product: ofatumumab with prf	Ofatumumab	1件: D09314 💬	1件: MS4A1 💬	1件: Hematopoietic cell lineage	1件: 13 💬
33	Combination product: prp combined magnovision	-	-	-	-	1件: 90 💬
34	Combination product: transcon pth	-	-	-	-	1件: 235 💬
35	Combination product: treprostinil via implanted pump	Treprostinil	1件: D06213 💬	1件: PTGIR 💬	3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction	1件: 86 💬
36	Combination product: twice daily 90 mg hydrocortisone acetate suppository administered with sephure applicator	Acetate	2件: D00088, D00165 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	1件: 97 💬
37	Combination steroid	-	-	-	-	1件: 46 💬
38	Combination therapy with vigabatrin and prednisolone	Prednisolone	9件: D00472, D00535, D00980, D00981, D00982, D01239, D01998, D02156, D03301 💬	2件: ABAT, NR3C1 💬	8件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Neuroactive ligand-receptor interaction, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism	1件: 145 💬
39	Continuation of current haart (boosted protease inhibitor [pi] combination + 2 nrtis)	-	-	-	-	1件: 265 💬
40	Conventional dmard combination	-	-	-	-	1件: 46 💬
41	Cytotoxic combination	-	-	-	-	1件: 56 💬
42	Device: abatacept combination product (acp)	Abatacept	1件: D03203 💬	2件: CD80, CD86 💬	12件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis	1件: 46 💬
43	Eflornithine plus nifurtimox combination therapy	Eflornithine	2件: D00833, D07883 💬	1件: ODC1 💬	3件: Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways	1件: 65 💬
44	Ezetimibe+simvastatin drug combination	Ezetimibe	2件: D00434, D01966 💬	2件: HMGCR, NPC1L1 💬	5件: AMPK signaling pathway, Bile secretion, Fat digestion and absorption, Metabolic pathways, Terpenoid backbone biosynthesis	1件: 49 💬
45	Fixed dose combination ciprofloxacin/celecoxib	Celecoxib	3件: D00186, D00567, D02216 💬	1件: PTGS2 💬	22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	1件:  2  💬
46	Infliximab and azathioprine combination at week 0	Azathioprine	3件: D00238, D02598, D03033 💬	1件: TNF 💬	65件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	1件: 96 💬
47	Infliximab and azathioprine combination at week 14	Azathioprine	3件: D00238, D02598, D03033 💬	1件: TNF 💬	65件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	1件: 96 💬
48	Lum/iva fixed-dose combination	-	-	-	-	1件: 299 💬
49	Lumacaftor plus ivacaftor combination	Ivacaftor	2件: D09916, D10134 💬	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	1件: 299 💬
50	Lumacaftor, ivacaftor drug combination	Ivacaftor	2件: D09916, D10134 💬	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	1件: 299 💬
51	Nebulized combination ipratropium bromide with salbutamol	Ipratropium	2件: D02147, D02212 💬	6件: ADRB2, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	17件: Adrenergic signaling in cardiomyocytes, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway	1件: 86 💬
52	Nifurtimox-eflronithine combination treatment (nect)	Nifurtimox	1件: D00833 💬	-	-	1件: 65 💬
53	Nutraceutical combination	-	-	-	-	1件: 96 💬
54	Other: ibuprofen and isosorbide dinitrate combination	Ibuprofen	6件: D00126, D00347, D00516, D01122, D04490, D06606 💬	2件: PTGS1, PTGS2 💬	23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	1件: 113 💬
55	Other: iv steroids combination alone	-	-	-	-	1件: 41 💬
56	Part 2, jm-010 combination group a	-	-	-	-	1件:  6  💬
57	Part 2, jm-010 combination group b	-	-	-	-	1件:  6  💬
58	Ph-combination therapy	-	-	-	-	2件: 86, 88 💬
59	Piperacillin-tazobactam combination product	Piperacillin	4件: D00466, D00660, D02251, D08380 💬	-	-	1件: 299 💬
60	Rapamycin-calcitriol combination	Calcitriol	2件: D00129, D00753 💬	2件: MTOR, VDR 💬	54件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Mineral absorption, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Tuberculosis, Type II diabetes mellitus, mTOR signaling pathway	1件: 158 💬
61	Rhtpo in combination with rituximab	Recombinant Human Thrombopoietin	1件: D02994 💬	1件: MS4A1 💬	1件: Hematopoietic cell lineage	1件: 63 💬
62	Tadalafil and ambrisentan upfront combination therapy	Ambrisentan	2件: D02008, D07077 💬	2件: EDNRA, PDE5A 💬	9件: Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	2件: 51, 86 💬
63	Tocilizumab and iv steroids combination	Tocilizumab	1件: D02596 💬	1件: IL6R 💬	12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor	1件: 41 💬
64	Triple combination therapy	-	-	-	-	1件: 299 💬
65	Ursodeoxycholic acid combination of immunosuppressive agents	Ursodeoxycholic acid	1件: D00734 💬	1件: NR1H4 💬	1件: Bile secretion	2件: 93, 95 💬
66	Von willebrand factor and coagulation factor viii in combination	Beroctocog alfa	-	-	-	1件: 288 💬
67	Vx-661 plus ivacaftor combination	Ivacaftor	1件: D09916 💬	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway	1件: 299 💬

先頭へ