DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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62 / 286 pathways

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
2	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
3	Adrenergic signaling in cardiomyocytes 💬	5件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
4	Alcoholism 💬	1件: DDC 💬	D00558 💬	Carbidopa	9件: 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬
5	Alcoholism 💬	2件: DRD1, DRD2 💬	D00059 💬	Levodopa	8件: 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
6	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
7	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
8	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
9	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
10	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
11	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
12	Amphetamine addiction 💬	2件: CACNA1C, CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
13	Amphetamine addiction 💬	2件: CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
14	Amphetamine addiction 💬	6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
15	Amphetamine addiction 💬	1件: DDC 💬	D00558 💬	Carbidopa	9件: 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬
16	Amphetamine addiction 💬	1件: DRD1 💬	D00059 💬	Levodopa	8件: 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
17	Amyotrophic lateral sclerosis 💬	2件: GRIA1, GRIA2 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
18	Arrhythmogenic right ventricular cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
19	Arrhythmogenic right ventricular cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
20	Arrhythmogenic right ventricular cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
21	Bile secretion 💬	1件: CA2 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
22	Calcium signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
23	Calcium signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
24	Calcium signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
25	Calcium signaling pathway 💬	2件: DRD1, DRD5 💬	D00059 💬	Levodopa	8件: 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
26	Calcium signaling pathway 💬	3件: HTR2A, HTR2B, HTR2C 💬	D07945 💬	Fenfluramine	3件: 140, 144, 145 💬
27	cAMP signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
28	cAMP signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
29	cAMP signaling pathway 💬	8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
30	cAMP signaling pathway 💬	3件: DRD1, DRD2, DRD5 💬	D00059 💬	Levodopa	8件: 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
31	Carbohydrate digestion and absorption 💬	1件: CACNA1D 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
32	Carbohydrate digestion and absorption 💬	1件: CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
33	Carbohydrate digestion and absorption 💬	1件: CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
34	Cardiac muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
35	Cardiac muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
36	Cardiac muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
37	Cellular senescence 💬	1件: CACNA1D 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
38	Cellular senescence 💬	1件: CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
39	Cellular senescence 💬	1件: CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
40	cGMP-PKG signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
41	cGMP-PKG signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
42	cGMP-PKG signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
43	Cholinergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
44	Cholinergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
45	Cholinergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
46	Circadian entrainment 💬	2件: CACNA1C, CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
47	Circadian entrainment 💬	2件: CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
48	Circadian entrainment 💬	6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
49	Cocaine addiction 💬	1件: DDC 💬	D00558 💬	Carbidopa	9件: 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬
50	Cocaine addiction 💬	2件: DRD1, DRD2 💬	D00059 💬	Levodopa	8件: 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
51	Cocaine addiction 💬	1件: GRIA2 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
52	Collecting duct acid secretion 💬	1件: CA2 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
53	Cortisol synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
54	Cortisol synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
55	Cortisol synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
56	Cushing syndrome 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
57	Cushing syndrome 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
58	Cushing syndrome 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
59	Dilated cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
60	Dilated cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
61	Dilated cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
62	Dopaminergic synapse 💬	2件: CACNA1C, CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
63	Dopaminergic synapse 💬	2件: CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
64	Dopaminergic synapse 💬	7件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, SCN1A 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
65	Dopaminergic synapse 💬	1件: DDC 💬	D00558 💬	Carbidopa	9件: 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬
66	Dopaminergic synapse 💬	5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬	D00059 💬	Levodopa	8件: 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
67	GABAergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
68	GABAergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
69	GABAergic synapse 💬	20件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
70	GABAergic synapse 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D01253 💬	Clobazam	2件: 140, 144 💬
71	Gap junction 💬	2件: DRD1, DRD2 💬	D00059 💬	Levodopa	8件: 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
72	Gap junction 💬	3件: HTR2A, HTR2B, HTR2C 💬	D07945 💬	Fenfluramine	3件: 140, 144, 145 💬
73	Gastric acid secretion 💬	1件: CA2 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
74	Glutamatergic synapse 💬	2件: CACNA1C, CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
75	Glutamatergic synapse 💬	2件: CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
76	Glutamatergic synapse 💬	11件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
77	GnRH secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
78	GnRH secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
79	GnRH secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
80	GnRH signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
81	GnRH signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
82	GnRH signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
83	Growth hormone synthesis, secretion and action 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
84	Growth hormone synthesis, secretion and action 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
85	Growth hormone synthesis, secretion and action 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
86	Huntington disease 💬	4件: GRIA1, GRIA2, GRIA3, GRIA4 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
87	Hypertrophic cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
88	Hypertrophic cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
89	Hypertrophic cardiomyopathy 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
90	Inflammatory mediator regulation of TRP channels 💬	3件: HTR2A, HTR2B, HTR2C 💬	D07945 💬	Fenfluramine	3件: 140, 144, 145 💬
91	Insulin secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
92	Insulin secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
93	Insulin secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
94	Long-term depression 💬	3件: GRIA1, GRIA2, GRIA3 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
95	Long-term potentiation 💬	1件: CACNA1C 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
96	Long-term potentiation 💬	1件: CACNA1C 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
97	Long-term potentiation 💬	3件: CACNA1C, GRIA1, GRIA2 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
98	MAPK signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
99	MAPK signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
100	MAPK signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
101	Metabolic pathways 💬	2件: CA2, CA4 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
102	Metabolic pathways 💬	1件: DDC 💬	D00558 💬	Carbidopa	9件: 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬
103	Morphine addiction 💬	1件: DRD1 💬	D00059 💬	Levodopa	8件: 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
104	Morphine addiction 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D01253 💬	Clobazam	2件: 140, 144 💬
105	Morphine addiction 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
106	Neuroactive ligand-receptor interaction 💬	2件: CNR1, CNR2 💬	D10915 💬	Cannabidiol	19件: 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
107	Neuroactive ligand-receptor interaction 💬	5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬	D00059 💬	Levodopa	8件: 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
108	Neuroactive ligand-receptor interaction 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D01253 💬	Clobazam	2件: 140, 144 💬
109	Neuroactive ligand-receptor interaction 💬	25件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
110	Neuroactive ligand-receptor interaction 💬	3件: HTR2A, HTR2B, HTR2C 💬	D07945 💬	Fenfluramine	3件: 140, 144, 145 💬
111	Nicotine addiction 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D01253 💬	Clobazam	2件: 140, 144 💬
112	Nicotine addiction 💬	20件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
113	Nitrogen metabolism 💬	2件: CA2, CA4 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
114	Oxytocin signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
115	Oxytocin signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
116	Oxytocin signaling pathway 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
117	Pancreatic secretion 💬	1件: CA2 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
118	Parkinson disease 💬	2件: DRD1, DRD2 💬	D00059 💬	Levodopa	8件: 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
119	Pathways of neurodegeneration - multiple diseases 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
120	Pathways of neurodegeneration - multiple diseases 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
121	Pathways of neurodegeneration - multiple diseases 💬	8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
122	Phenylalanine metabolism 💬	1件: DDC 💬	D00558 💬	Carbidopa	9件: 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬
123	Prion disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
124	Prion disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
125	Prion disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
126	Proximal tubule bicarbonate reclamation 💬	2件: CA2, CA4 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
127	Rap1 signaling pathway 💬	1件: CNR1 💬	D10915 💬	Cannabidiol	19件: 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
128	Rap1 signaling pathway 💬	1件: DRD2 💬	D00059 💬	Levodopa	8件: 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
129	Renin secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
130	Renin secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
131	Renin secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
132	Retrograde endocannabinoid signaling 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
133	Retrograde endocannabinoid signaling 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
134	Retrograde endocannabinoid signaling 💬	24件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
135	Retrograde endocannabinoid signaling 💬	1件: CNR1 💬	D10915 💬	Cannabidiol	19件: 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
136	Retrograde endocannabinoid signaling 💬	16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬	D01253 💬	Clobazam	2件: 140, 144 💬
137	Serotonergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
138	Serotonergic synapse 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
139	Serotonergic synapse 💬	7件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRB1, GABRB2, GABRB3 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
140	Serotonergic synapse 💬	1件: DDC 💬	D00558 💬	Carbidopa	9件: 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬
141	Serotonergic synapse 💬	3件: GABRB1, GABRB2, GABRB3 💬	D01253 💬	Clobazam	2件: 140, 144 💬
142	Serotonergic synapse 💬	4件: HTR2A, HTR2B, HTR2C, SLC6A4 💬	D07945 💬	Fenfluramine	3件: 140, 144, 145 💬
143	Spinocerebellar ataxia 💬	3件: GRIA1, GRIA2, GRIA3 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
144	Synaptic vesicle cycle 💬	1件: SLC6A4 💬	D07945 💬	Fenfluramine	3件: 140, 144, 145 💬
145	Taste transduction 💬	1件: CACNA1C 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
146	Taste transduction 💬	1件: CACNA1C 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
147	Taste transduction 💬	10件: CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
148	Taste transduction 💬	6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D01253 💬	Clobazam	2件: 140, 144 💬
149	Thermogenesis 💬	1件: CNR1 💬	D10915 💬	Cannabidiol	19件: 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
150	Tight junction 💬	1件: CACNA1D 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
151	Tight junction 💬	1件: CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
152	Tight junction 💬	1件: CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
153	Transcriptional misregulation in cancer 💬	1件: GRIA3 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
154	Tryptophan metabolism 💬	1件: DDC 💬	D00558 💬	Carbidopa	9件: 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬
155	Type II diabetes mellitus 💬	2件: CACNA1C, CACNA1D 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
156	Type II diabetes mellitus 💬	2件: CACNA1C, CACNA1D 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
157	Type II diabetes mellitus 💬	2件: CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
158	Tyrosine metabolism 💬	1件: DDC 💬	D00558 💬	Carbidopa	9件: 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬
159	Vascular smooth muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	5件: 6 , 140, 144, 156, 193 💬
160	Vascular smooth muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
161	Vascular smooth muscle contraction 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬

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