Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Acute myeloid leukemia 💬	1件: KIT 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2	Acute myeloid leukemia 💬	1件: KIT 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3	AGE-RAGE signaling pathway in diabetic complications 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
4	Axon guidance 💬	1件: ABL1 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
5	Axon guidance 💬	1件: ABL1 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
6	Bladder cancer 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
7	Breast cancer 💬	1件: KIT 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
8	Breast cancer 💬	1件: KIT 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
9	Calcium signaling pathway 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
10	Calcium signaling pathway 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
11	Calcium signaling pathway 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
12	Cell cycle 💬	1件: ABL1 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
13	Cell cycle 💬	1件: ABL1 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
14	Central carbon metabolism in cancer 💬	2件: KIT, PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
15	Central carbon metabolism in cancer 💬	2件: KIT, PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
16	Choline metabolism in cancer 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
17	Choline metabolism in cancer 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
18	Chronic myeloid leukemia 💬	1件: ABL1 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
19	Chronic myeloid leukemia 💬	1件: ABL1 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
20	EGFR tyrosine kinase inhibitor resistance 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
21	EGFR tyrosine kinase inhibitor resistance 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
22	EGFR tyrosine kinase inhibitor resistance 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
23	Endocytosis 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
24	Endocytosis 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
25	ErbB signaling pathway 💬	1件: ABL1 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
26	ErbB signaling pathway 💬	1件: ABL1 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
27	Fluid shear stress and atherosclerosis 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
28	Focal adhesion 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
29	Focal adhesion 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
30	Focal adhesion 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
31	Gap junction 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
32	Gap junction 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
33	Glioma 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
34	Glioma 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
35	Hematopoietic cell lineage 💬	1件: KIT 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
36	Hematopoietic cell lineage 💬	1件: KIT 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
37	HIF-1 signaling pathway 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
38	Human cytomegalovirus infection 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
39	Human cytomegalovirus infection 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
40	Human cytomegalovirus infection 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
41	Human papillomavirus infection 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
42	JAK-STAT signaling pathway 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
43	JAK-STAT signaling pathway 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
44	Kaposi sarcoma-associated herpesvirus infection 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
45	MAPK signaling pathway 💬	2件: KIT, PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
46	MAPK signaling pathway 💬	2件: KIT, PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
47	MAPK signaling pathway 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
48	Melanogenesis 💬	1件: KIT 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
49	Melanogenesis 💬	1件: KIT 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
50	Melanoma 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
51	Melanoma 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
52	MicroRNAs in cancer 💬	2件: ABL1, PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
53	MicroRNAs in cancer 💬	2件: ABL1, PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
54	MicroRNAs in cancer 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
55	Neurotrophin signaling pathway 💬	1件: ABL1 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
56	Neurotrophin signaling pathway 💬	1件: ABL1 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
57	Pancreatic cancer 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
58	Pathogenic Escherichia coli infection 💬	1件: ABL1 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
59	Pathogenic Escherichia coli infection 💬	1件: ABL1 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
60	Pathways in cancer 💬	3件: ABL1, KIT, PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
61	Pathways in cancer 💬	3件: ABL1, KIT, PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
62	Pathways in cancer 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
63	Phospholipase D signaling pathway 💬	2件: KIT, PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
64	Phospholipase D signaling pathway 💬	2件: KIT, PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
65	PI3K-Akt signaling pathway 💬	2件: KIT, PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
66	PI3K-Akt signaling pathway 💬	2件: KIT, PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
67	PI3K-Akt signaling pathway 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
68	Prostate cancer 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
69	Prostate cancer 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
70	Proteoglycans in cancer 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
71	Rap1 signaling pathway 💬	2件: KIT, PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
72	Rap1 signaling pathway 💬	2件: KIT, PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
73	Rap1 signaling pathway 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
74	Ras signaling pathway 💬	3件: ABL1, KIT, PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
75	Ras signaling pathway 💬	3件: ABL1, KIT, PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
76	Ras signaling pathway 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
77	Regulation of actin cytoskeleton 💬	1件: PDGFRA 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
78	Regulation of actin cytoskeleton 💬	1件: PDGFRA 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
79	Relaxin signaling pathway 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
80	Renal cell carcinoma 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
81	Rheumatoid arthritis 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
82	VEGF signaling pathway 💬	1件: VEGFA 💬	D06409 💬	Bevacizumab	9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
83	Viral myocarditis 💬	1件: ABL1 💬	D01441 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
84	Viral myocarditis 💬	1件: ABL1 💬	D08066 💬	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬

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