DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

A B C D E F G H I J K L M N O PQR S T U V WXYZother

131 / 286 pathways

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Acute myeloid leukemia 💬	2件: PML, RARA 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
2	Adherens junction 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
3	Adherens junction 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
4	Adipocytokine signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
5	Adipocytokine signaling pathway 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
6	Adipocytokine signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
7	African trypanosomiasis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
8	AGE-RAGE signaling pathway in diabetic complications 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
9	Allograft rejection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
10	Alzheimer disease 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
11	Amoebiasis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
12	AMPK signaling pathway 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
13	Amyotrophic lateral sclerosis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
14	Antifolate resistance 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
15	Antifolate resistance 💬	1件: TYMS 💬	D01223 💬	Capecitabine	1件: 94 💬
16	Antigen processing and presentation 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
17	Apoptosis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
18	Arrhythmogenic right ventricular cardiomyopathy 💬	2件: ITGA4, ITGB7 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
19	Asthma 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
20	Bile secretion 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
21	Bile secretion 💬	1件: NR1H4 💬	D00734 💬	Ursodeoxycholic acid	13件: 6 , 8 , 20, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
22	Bladder cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
23	Bladder cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
24	Breast cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
25	Breast cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
26	C-type lectin receptor signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
27	Calcium signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
28	Calcium signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
29	cAMP signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
30	cAMP signaling pathway 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
31	Cell adhesion molecules 💬	2件: ITGA4, ITGB7 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
32	Central carbon metabolism in cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
33	Central carbon metabolism in cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
34	Chagas disease 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
35	Chemokine signaling pathway 💬	2件: CCR2, CCR5 💬	D09878 💬	Cenicriviroc	1件: 94 💬
36	Choline metabolism in cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
37	Choline metabolism in cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
38	Colorectal cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
39	Colorectal cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
40	Coronavirus disease - COVID-19 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
41	Coronavirus disease - COVID-19 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
42	Coronavirus disease - COVID-19 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
43	Cushing syndrome 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
44	Cushing syndrome 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
45	Cytokine-cytokine receptor interaction 💬	2件: CCR2, CCR5 💬	D09878 💬	Cenicriviroc	1件: 94 💬
46	Cytokine-cytokine receptor interaction 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
47	Diabetic cardiomyopathy 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
48	Diabetic cardiomyopathy 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
49	Dilated cardiomyopathy 💬	2件: ITGA4, ITGB7 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
50	Dilated cardiomyopathy 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
51	Drug metabolism - other enzymes 💬	2件: IMPDH1, IMPDH2 💬	D01392 💬	Mizoribine	8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
52	Drug metabolism - other enzymes 💬	1件: RRM1 💬	D01370 💬	Cladribine	2件: 13, 94 💬
53	ECM-receptor interaction 💬	2件: ITGA4, ITGB7 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
54	EGFR tyrosine kinase inhibitor resistance 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
55	EGFR tyrosine kinase inhibitor resistance 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
56	Endocrine resistance 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
57	Endocrine resistance 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
58	Endocytosis 💬	1件: CCR5 💬	D09878 💬	Cenicriviroc	1件: 94 💬
59	Endocytosis 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
60	Endocytosis 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
61	Endocytosis 💬	1件: PML 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
62	Endometrial cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
63	Endometrial cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
64	Epithelial cell signaling in Helicobacter pylori infection 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
65	Epithelial cell signaling in Helicobacter pylori infection 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
66	Epstein-Barr virus infection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
67	ErbB signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
68	ErbB signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
69	Estrogen signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
70	Estrogen signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
71	Estrogen signaling pathway 💬	1件: RARA 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
72	Fc epsilon RI signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
73	Fluid shear stress and atherosclerosis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
74	Focal adhesion 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
75	Focal adhesion 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
76	Focal adhesion 💬	2件: ITGA4, ITGB7 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
77	FoxO signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
78	FoxO signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
79	Gap junction 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
80	Gap junction 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
81	Gastric cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
82	Gastric cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
83	Gastric cancer 💬	1件: RARB 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
84	Glioma 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
85	Glioma 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
86	Glucagon signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
87	Glucagon signaling pathway 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
88	Glutathione metabolism 💬	1件: RRM1 💬	D01370 💬	Cladribine	2件: 13, 94 💬
89	GnRH signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
90	GnRH signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
91	Graft-versus-host disease 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
92	Hematopoietic cell lineage 💬	1件: ITGA4 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
93	Hematopoietic cell lineage 💬	1件: MS4A1 💬	D02994 💬	Rituximab	47件: 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
94	Hematopoietic cell lineage 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
95	Hepatitis B 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
96	Hepatitis C 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
97	Hepatitis C 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
98	Hepatitis C 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
99	Hepatitis C 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
100	Hepatitis C 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
101	Hepatocellular carcinoma 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
102	Hepatocellular carcinoma 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
103	Herpes simplex virus 1 infection 💬	1件: PML 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
104	Herpes simplex virus 1 infection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
105	HIF-1 signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
106	HIF-1 signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
107	Human cytomegalovirus infection 💬	1件: CCR5 💬	D09878 💬	Cenicriviroc	1件: 94 💬
108	Human cytomegalovirus infection 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
109	Human cytomegalovirus infection 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
110	Human cytomegalovirus infection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
111	Human immunodeficiency virus 1 infection 💬	1件: CCR5 💬	D09878 💬	Cenicriviroc	1件: 94 💬
112	Human immunodeficiency virus 1 infection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
113	Human papillomavirus infection 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
114	Human papillomavirus infection 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
115	Human papillomavirus infection 💬	2件: ITGA4, ITGB7 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
116	Human papillomavirus infection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
117	Human T-cell leukemia virus 1 infection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
118	Hypertrophic cardiomyopathy 💬	2件: ITGA4, ITGB7 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
119	Hypertrophic cardiomyopathy 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
120	IL-17 signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
121	Inflammatory bowel disease 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
122	Influenza A 💬	1件: PML 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
123	Influenza A 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
124	Insulin resistance 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
125	Insulin resistance 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
126	Insulin resistance 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
127	Intestinal immune network for IgA production 💬	2件: ITGA4, ITGB7 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
128	JAK-STAT signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
129	JAK-STAT signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
130	Kaposi sarcoma-associated herpesvirus infection 💬	1件: CCR5 💬	D09878 💬	Cenicriviroc	1件: 94 💬
131	Legionellosis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
132	Leishmaniasis 💬	1件: ITGA4 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
133	Leishmaniasis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
134	Leukocyte transendothelial migration 💬	1件: ITGA4 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
135	Malaria 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
136	MAPK signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
137	MAPK signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
138	MAPK signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
139	Melanoma 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
140	Melanoma 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
141	Metabolic pathways 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
142	Metabolic pathways 💬	2件: IMPDH1, IMPDH2 💬	D01392 💬	Mizoribine	8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
143	Metabolic pathways 💬	1件: RRM1 💬	D01370 💬	Cladribine	2件: 13, 94 💬
144	Metabolic pathways 💬	1件: TYMS 💬	D01223 💬	Capecitabine	1件: 94 💬
145	MicroRNAs in cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
146	MicroRNAs in cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
147	mTOR signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
148	Natural killer cell mediated cytotoxicity 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
149	Necroptosis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
150	Neuroactive ligand-receptor interaction 💬	1件: NR3C1 💬	D00246 💬	Budesonide	9件: 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
151	NF-kappa B signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
152	NOD-like receptor signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
153	Non-alcoholic fatty liver disease 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
154	Non-alcoholic fatty liver disease 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
155	Non-alcoholic fatty liver disease 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
156	Non-small cell lung cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
157	Non-small cell lung cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
158	Non-small cell lung cancer 💬	1件: RARB 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
159	One carbon pool by folate 💬	1件: TYMS 💬	D01223 💬	Capecitabine	1件: 94 💬
160	Osteoclast differentiation 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
161	Oxytocin signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
162	Oxytocin signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
163	Pancreatic cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
164	Pancreatic cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
165	Parathyroid hormone synthesis, secretion and action 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
166	Parathyroid hormone synthesis, secretion and action 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
167	Pathogenic Escherichia coli infection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
168	Pathways in cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
169	Pathways in cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
170	Pathways in cancer 💬	3件: PML, RARA, RARB 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
171	Pathways of neurodegeneration - multiple diseases 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
172	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
173	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
174	Pertussis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
175	Phospholipase D signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
176	Phospholipase D signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
177	PI3K-Akt signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
178	PI3K-Akt signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
179	PI3K-Akt signaling pathway 💬	2件: ITGA4, ITGB7 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
180	PPAR signaling pathway 💬	1件: PPARA 💬	D01366 💬	Bezafibrate	6件: 20, 93, 94, 160, 316, 324 💬
181	PPAR signaling pathway 💬	1件: PPARA 💬	D00565 💬	Fenofibrate	5件: 8 , 79, 93, 94, 265 💬
182	Prion disease 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
183	Prostate cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
184	Prostate cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
185	Proteoglycans in cancer 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
186	Proteoglycans in cancer 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
187	Proteoglycans in cancer 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
188	Purine metabolism 💬	2件: IMPDH1, IMPDH2 💬	D01392 💬	Mizoribine	8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
189	Purine metabolism 💬	1件: RRM1 💬	D01370 💬	Cladribine	2件: 13, 94 💬
190	Pyrimidine metabolism 💬	1件: RRM1 💬	D01370 💬	Cladribine	2件: 13, 94 💬
191	Pyrimidine metabolism 💬	1件: TYMS 💬	D01223 💬	Capecitabine	1件: 94 💬
192	Rap1 signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
193	Rap1 signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
194	Ras signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
195	Ras signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
196	Regulation of actin cytoskeleton 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
197	Regulation of actin cytoskeleton 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
198	Regulation of actin cytoskeleton 💬	2件: ITGA4, ITGB7 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
199	Relaxin signaling pathway 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
200	Relaxin signaling pathway 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
201	Rheumatoid arthritis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
202	RIG-I-like receptor signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
203	Salmonella infection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
204	Shigellosis 💬	1件: EGFR 💬	D04023 💬	Erlotinib	1件: 94 💬
205	Shigellosis 💬	1件: EGFR 💬	D07907 💬	Erlotinib	1件: 94 💬
206	Shigellosis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
207	Small cell lung cancer 💬	1件: RARB 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
208	Sphingolipid signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
209	Systemic lupus erythematosus 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
210	T cell receptor signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
211	Terpenoid backbone biosynthesis 💬	1件: HMGCR 💬	D00434 💬	Simvastatin	21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
212	TGF-beta signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
213	Th17 cell differentiation 💬	1件: RARA 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
214	TNF signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
215	Toll-like receptor signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
216	Toxoplasmosis 💬	1件: CCR5 💬	D09878 💬	Cenicriviroc	1件: 94 💬
217	Toxoplasmosis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
218	Transcriptional misregulation in cancer 💬	1件: ITGB7 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
219	Transcriptional misregulation in cancer 💬	2件: PML, RARA 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
220	Tuberculosis 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
221	Type I diabetes mellitus 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
222	Type II diabetes mellitus 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
223	Ubiquitin mediated proteolysis 💬	1件: PML 💬	D00094 💬	Tretinoin	5件: 2 , 63, 75, 94, 231 💬
224	Viral carcinogenesis 💬	1件: CCR5 💬	D09878 💬	Cenicriviroc	1件: 94 💬
225	Viral protein interaction with cytokine and cytokine receptor 💬	2件: CCR2, CCR5 💬	D09878 💬	Cenicriviroc	1件: 94 💬
226	Viral protein interaction with cytokine and cytokine receptor 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
227	Yersinia infection 💬	1件: ITGA4 💬	D08083 💬	Vedolizumab	3件: 94, 96, 97 💬
228	Yersinia infection 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬

先頭へ