DDrare: Database of Drug Development for Rare Diseases

230. 肺胞低換気症候群
［臨床試験数：8，薬物数：11（DrugBank：5），標的遺伝子数：18，標的パスウェイ数：27］

Searched query = "Alveolar hypoventilation syndrome", "AHS", "Hypoventilation syndrome", "OHS", "CCHS", "Idiopathic central alveolar hypoventilation", "ICAH"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = Acetazolamide; Cerazette; Desogestrel; Domperidone; Désogestrel; Equal; Gold; Ketogenic Diet; Motilium; Other: BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (arterial blood gas and metabolic panel) and data collection from PSG study.; Other: BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (venous blood gas and metabolic panel) and data collection from PSG study.

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01499485 (ClinicalTrials.gov)	November 2011	20/12/2011	Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation.	Effects of Acetazolamide on the Duration of Mechanical Ventilation in Patients With Metabolic Alkalosis. Phase III Multicenter Double-blinded Clinical Trial.	Pulmonary Disease, Chronic Obstructive;Obesity Hypoventilation Syndrome;Metabolic Alkalosis	Drug: Acetazolamide;Drug: Placebo	Hospital Son Llatzer	NULL	Completed	18 Years	N/A	Both	140	Phase 3	Spain

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT01499485
(ClinicalTrials.gov)

November 2011

20/12/2011

Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation.

Effects of Acetazolamide on the Duration of Mechanical Ventilation in Patients With Metabolic Alkalosis. Phase III Multicenter Double-blinded Clinical Trial.

Pulmonary Disease, Chronic Obstructive;Obesity Hypoventilation Syndrome;Metabolic Alkalosis

Drug: Acetazolamide;Drug: Placebo

Hospital Son Llatzer

NULL

Completed

18 Years

N/A

Both

140

Phase 3

Spain