DDrare: Database of Drug Development for Rare Diseases

278. 巨大リンパ管奇形（頚部顔面病変）
［臨床試験数：19，薬物数：23（DrugBank：7），標的遺伝子数：5，標的パスウェイ数：62］

Searched query = "Huge lymphatic malformation with cervicofacial lesion", "Huge lymphatic malformation", "Lymphatic malformation"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = Bleomycin; Device: MRI; Indocyanine green; L04AA10; OK432; Picibanil; Propranolol; RAPAMUNE; Rapamune; Rapamycin; Rapamycin dosage; SIROLIMUS; Selenium; Sildenafil; Sildenafil 20 mg tablets; Sirolimus; Sirolimus 0,1% crème; Sirolimus 1mg/mL; Sirolimus Oral Liquid Product 1mg/mL; Topical 0.1% Sirolimus; Topical Vehicle; VT30; Water

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03972592 (ClinicalTrials.gov)	June 5, 2019	24/5/2019	Topical Sirolimus in Cutaneous Lymphatic Malformations	0.1% Topical Sirolimus in the Treatment of Cutaneous Microcystic Lymphatic Malformations in Children and Adults: Phase II, Split-body Randomized, Double-blind, Vehicle-controlled Clinical Trial	Vascular Malformations;Lymphatic Malformation	Drug: Topical 0.1% Sirolimus;Drug: Topical Vehicle	University Hospital, Tours	University Hospital, Angers	Recruiting	6 Years	N/A	All	55	Phase 2	France

No.

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Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

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sponsor

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sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT03972592
(ClinicalTrials.gov)

June 5, 2019

24/5/2019

Topical Sirolimus in Cutaneous Lymphatic Malformations

0.1% Topical Sirolimus in the Treatment of Cutaneous Microcystic Lymphatic Malformations in Children and Adults: Phase II, Split-body Randomized, Double-blind, Vehicle-controlled Clinical Trial

Vascular Malformations;Lymphatic Malformation

Drug: Topical 0.1% Sirolimus;Drug: Topical Vehicle

University Hospital, Tours

University Hospital, Angers

Recruiting

6 Years

N/A

All

Phase 2

France