DDrare: Database of Drug Development for Rare Diseases

294. 先天性横隔膜ヘルニア
［臨床試験数：12，薬物数：29（DrugBank：6），標的遺伝子数：5，標的パスウェイ数：14］

Searched query = "Congenital diaphragmatic hernia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = Autologous umbilical cord blood; Bronchodilator Response; Diagnostic Test: Fecal microbiome probiotic; Diagnostic Test: Functional residual capacity; Diagnostic Test: Maximum oxygen uptake; Diagnostic Test: Pulmonary microbiome probiotic; Diagnostic Test: VOC probiotic; Diagnostic Test: initial VOC; Diagnostic Test: initial fecal microbiome; Diagnostic Test: initial pulmonary microbiome; Gold; Hypersaline; INOmax; INOmax 800ppm mol/mol inhalatiegas; Inomax; Losec; Milrinone; NITRIC OXIDE; Neophyr 1000ppm mol/mol; Nitric Oxide; Omeprazol; Omeprazole; Omeprazole rectally 1mg/kg; Oxygen; Probiotic treatment; Procedure: Repair of CDH w/Alloderm; Procedure: Repair of CDH w/SIS Gold; Revatio 0.8mg/ml solution for injection; Sildenafil

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02951130 (ClinicalTrials.gov)	August 22, 2017	14/10/2016	Milrinone in Congenital Diaphragmatic Hernia	Milrinone in Congenital Diaphragmatic Hernia	Congenital Diaphragmatic Hernia;Persistent Pulmonary Hypertension of the Newborn;Hypoxemic Respiratory Failure;Pulmonary Hypoplasia	Drug: Milrinone;Drug: Placebo (5% Dextrose)	NICHD Neonatal Research Network	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Recruiting	N/A	168 Hours	All	66	Phase 2	United States

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT02951130
(ClinicalTrials.gov)

August 22, 2017

14/10/2016

Milrinone in Congenital Diaphragmatic Hernia

Congenital Diaphragmatic Hernia;Persistent Pulmonary Hypertension of the Newborn;Hypoxemic Respiratory Failure;Pulmonary Hypoplasia

Drug: Milrinone;Drug: Placebo (5% Dextrose)

NICHD Neonatal Research Network

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Recruiting

N/A

168 Hours

All

Phase 2

United States