DDrare: Database of Drug Development for Rare Diseases

39. 中毒性表皮壊死症
［臨床試験数：11，薬物数：18（DrugBank：8），標的遺伝子数：11，標的パスウェイ数：101］

Searched query = "Toxic epidermal necrolysis", "Toxic epidermal necrosis", "TEN"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = Clobetasol; Clobetasol 0.05% ointment; Cyclosporine; Cyclosporine 5 mg/kg bid days 0-14; Etanercept; Etanercept 50 mg sc day 0 and day 3; Harmonized supportive care; Infliximab; Intravenous immunoglobulin; Isotretinoin; Methylprednisolone; NaCl 0.9%; Palifermin; Prednisolone; Recombinant granulocyte - colony stimulating factor; Remicaide (infliximab); Site specific standard of care comparison; Topical infliximab

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02037347 (ClinicalTrials.gov)	October 2010	13/1/2014	Study to Evaluate the Use of Palifermin to Treat Toxic Epidermal Necrolysis	Palifermin Treatment of Toxic Epidermal Necrolysis	Toxic Epidermal Necrolysis;Stevens-Johnson Syndrome	Drug: Palifermin	Brett King	Swedish Orphan Biovitrum	Terminated	18 Years	N/A	All	1	Phase 1;Phase 2	United States

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT02037347
(ClinicalTrials.gov)

October 2010

13/1/2014

Study to Evaluate the Use of Palifermin to Treat Toxic Epidermal Necrolysis

Palifermin Treatment of Toxic Epidermal Necrolysis

Toxic Epidermal Necrolysis;Stevens-Johnson Syndrome

Drug: Palifermin

Brett King

Swedish Orphan Biovitrum

Terminated

18 Years

N/A

All

Phase 1;Phase 2

United States