DDrare: Database of Drug Development for Rare Diseases

40. 高安動脈炎
［臨床試験数：22，薬物数：46（DrugBank：20），標的遺伝子数：22，標的パスウェイ数：111］

Searched query = "Takayasu arteritis", "Aortitis syndrome", "Pulseless disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = AZA; Acetate; Adalimumab; Anti-thymocyte globulin; CYC; Clofarabine; Cyclophosphamide; Cyclosporine; DCB; Filgrastim; Glucocorticoids; INFLIXIMAB; Infliximab; Leflunomide; Leflunomide 10mg Tab; MMF; MTX; Methotrexate; Methotrexate Tablets; Methylprednisolone; Naltrexone; Naltrexone Hydrochloride; Placebo; Prednisolone; Prednisone; Prednisone Acetate; Prednisone acetate; Prednisone, cyclophosphamide; Procedure: Autologous Peripheral Blood Stem Cell Transplantation; Procedure: Computed Tomography; Procedure: Digital substraction angiography (DSA); Procedure: Drug coated balloon (DCB); Procedure: Positron Emission Tomography; Radiation: Fluorine F 18 Clofarabine; Remicade; Remicade (anti tumor necrosis factor inhibitor); RoActemra; RoActemra 20mg/ml; TOCILIZUMAB; Tocilizumab; Tocilizumab (MRA-SC); Tofacitinib; Tofacitinib tablet; Upadacitinib; Yellow Fever Vaccine; Yellow Fever vaccine (17D)

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02981979 (ClinicalTrials.gov)	December 2016	22/11/2016	Takayasu Arteritis Clinical Trial in China	Comparison of the Efficacy and Safety of Leflunomide Versus Placebo Combine With the Basic Prednisone Therapy in Patients With Active Phase of Takayasu's Arteritis: a Randomized Controlled Double-blinded Trial	Takayasu Arteritis	Drug: Leflunomide 10mg Tab;Drug: Prednisone Acetate;Drug: Placebos	Jiang lindi	NULL	Unknown status	18 Years	65 Years	All	116	N/A	China
2	NCT03893136 (ClinicalTrials.gov)	November 1, 2016	12/3/2019	The Registry Study of Takayasu Arteritis in East China	The Cohort Study of East Chinese Takayasu's Arteritis (ECTA-cohort Study)	Takayasu Arteritis;Mechanisms, Defense;Pregnancy Related;Treatment Refusal;Outcome	Biological: Tocilizumab;Drug: Leflunomide	Shanghai Zhongshan Hospital	NULL	Recruiting	18 Years	65 Years	All	1000		China

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT02981979
(ClinicalTrials.gov)

December 2016

22/11/2016

Takayasu Arteritis Clinical Trial in China

Comparison of the Efficacy and Safety of Leflunomide Versus Placebo Combine With the Basic Prednisone Therapy in Patients With Active Phase of Takayasu's Arteritis: a Randomized Controlled Double-blinded Trial

Takayasu Arteritis

Drug: Leflunomide 10mg Tab;Drug: Prednisone Acetate;Drug: Placebos

Jiang lindi

NULL

Unknown status

18 Years

65 Years

All

116

N/A

China

NCT03893136
(ClinicalTrials.gov)

November 1, 2016

12/3/2019

The Registry Study of Takayasu Arteritis in East China

The Cohort Study of East Chinese Takayasu's Arteritis (ECTA-cohort Study)

Takayasu Arteritis;Mechanisms, Defense;Pregnancy Related;Treatment Refusal;Outcome

Biological: Tocilizumab;Drug: Leflunomide

Shanghai Zhongshan Hospital

NULL

Recruiting

18 Years

65 Years

All

1000

China