46. 悪性関節リウマチ
[臨床試験数:4,183,薬物数:2,538(DrugBank:401),標的遺伝子数:183,標的パスウェイ数:219

Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
8 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00235872
(ClinicalTrials.gov)
August 20047/10/2005Adalimumab in Adult Japanese Subjects With Rheumatoid ArthritisOpen-Label Continuous Administration Study With Adalimumab (D2E7) in Subjects With Rheumatoid ArthritisRheumatoid ArthritisBiological: adalimumabAbbottAbbott Japan Co.,Ltd;Eisai Co., Ltd.Completed20 YearsN/AAll309Phase 3Japan
2NCT00649545
(ClinicalTrials.gov)
July 200327/3/2008Study of the Human Anti-TNF Monoclonal Antibody in Patients With Active Rheumatoid ArthritisA Multi-Center Study of the Safety and Efficacy of Human Anti-TNF Monoclonal Antibody Adalimumab (D2E7) in Patients With Active Rheumatoid ArthritisRheumatoid ArthritisBiological: adalimumabAbbottNULLApproved for marketing18 YearsN/ABothN/ANULL
3NCT00235833
(ClinicalTrials.gov)
June 20037/10/2005Adalimumab in Adult Japanese Subjects With Rheumatoid ArthritisLong-term Continuously Repeated Dose Study of Adalimumab (D2E7) in Patients With Rheumatoid ArthritisRheumatoid ArthritisBiological: adalimumabAbbottAbbott Japan Co.,Ltd;Eisai Co., Ltd.Completed20 YearsN/AAll25Phase 2Japan
4NCT00234845
(ClinicalTrials.gov)
March 200313/9/2005Adalimumab in Combination With Methotrexate vs Methotrexate Alone in Early Rheumatoid ArthritisA Multi-Centre Randomized, Double-Blind Study Comparing Adalimumab (D2E7) Plus Methotrexate With Placebo Plus Methotrexate on Work Disability in Subjects With Early Rheumatoid ArthritisRheumatoid ArthritisDrug: adalimumab;Drug: methotrexateAbbottNULLCompleted18 YearsN/ABoth148Phase 3United States
5NCT00448383
(ClinicalTrials.gov)
September 200214/3/2007A Study to Assess the Safety and Efficacy of Adalimumab When Added to Inadequate Standard Anti-Rheumatic Therapy in Patients With Active Rheumatoid ArthritisAn Open-Label, Multi-Center Study to Assess the Safety and Efficacy of the Fully Human Anti-TNF-a Monoclonal Antibody Adalimumab (D2E7) When Added to Inadequate Standard Anti-Rheumatic Therapy in Patients With Active Rheumatoid ArthritisRheumatoid ArthritisBiological: adalimumabAbbottNULLCompleted18 YearsN/ABoth6610Phase 3NULL
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6NCT00049751
(ClinicalTrials.gov)
September 200213/11/2002Study of Human Anti-TNF Monoclonal Antibody D2E7 in Subjects With Active Rheumatoid ArthritisA Multicenter Study of the Safety of Human Anti-TNF Monoclonal Antibody D2E7 in Subjects With Active Rheumatoid ArthritisRheumatoid ArthritisDrug: AdalimumabAbbottNULLCompleted18 YearsN/ABoth3000Phase 3United States
7NCT00195650
(ClinicalTrials.gov)
July 200013/9/2005Long Term Open Label Continuation StudyA Multi-Center Continuation Study of the Human Anti-TNF Antibody D2E7 Administered as a Subcutaneous Injection in Patients With Rheumatoid ArthritisRheumatoid ArthritisBiological: AdalimumabAbbottNULLCompleted18 YearsN/AAll846Phase 3United States;Canada
8NCT00233571
(ClinicalTrials.gov)
June 200013/9/2005A Long Term Roll-over Study to Investigate the Efficacy and Safety of Adalimumab Given Long-term to Patients With Rheumatoid ArthritisA Multi-Centre Open Label Continuation Study With Subcutaneous D2E7 (Adalimumab) for Patients With Rheumatoid Arthritis Who Completed a Preceding Clinical Study With D2E7 (Adalimumab)Rheumatoid ArthritisBiological: Adalimumab 40 mg subcutaneous (SC) every other week (EOW)AbbottNULLCompleted18 YearsN/ABoth796Phase 3NULL