DDrare: Database of Drug Development for Rare Diseases

57. 特発性拡張型心筋症
［臨床試験数：12，薬物数：25（DrugBank：12），標的遺伝子数：9，標的パスウェイ数：33］

Searched query = "Idiopathic dilated cardiomyopathy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = 18F-deoxyglucose (FDG); Allopurinol; Benazepril; Carvedilol; Coenzyme Q10; Dobutamine; Doxazosin; GRANOCYTE - 34 million IU (Lenograstim rHuG-CSF); Granocyte; Granocyte Lenograstim; Granulocyte Colony Stimulating Factor; Granulocyte colony stimulating factor (GCSF); HTEA; Honey; Infusion of autologous mononuclear bone marrow cells; Lenograstim; Metoprolol; Metoprolol succinate; Metoprolol succinate + doxazosin; Mono Nuclear Cell (MNC) transplantation; PL 12185/0002 & PL 12185/0005(WATER FOR INJECTION); Procedure: bone marrow mononuclear cells; Umbilical cord mesenchymal stem cells; Valsartan; Water

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01917149 (ClinicalTrials.gov)	March 2005	30/7/2013	Supramaximal Titrated Inhibition of RAAS in Dilated Cardiomyopathy	Efficacy and Safety Study of Supramaximal Titrated Inhibition of RAAS in Idiopathic Dilated Cardiomyopathy	Dilated Cardiomyopathy	Drug: Benazepril;Drug: Valsartan;Drug: Metoprolol	Xijing Hospital	NULL	Completed	18 Years	70 Years	Both	480	Phase 4	China
2	NCT01798992 (ClinicalTrials.gov)	September 2000	22/2/2013	Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart	Beta-blocker Effect on Structural Remodeling and Gene Expression in the Failing Human Heart	Idiopathic Dilated Cardiomyopathy	Drug: Carvedilol;Drug: Metoprolol succinate;Drug: Metoprolol succinate + doxazosin	University of Colorado, Denver	National Heart, Lung, and Blood Institute (NHLBI);GlaxoSmithKline;AstraZeneca	Completed	18 Years	N/A	All	56	Phase 4	United States

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT01917149
(ClinicalTrials.gov)

March 2005

30/7/2013

Supramaximal Titrated Inhibition of RAAS in Dilated Cardiomyopathy

Efficacy and Safety Study of Supramaximal Titrated Inhibition of RAAS in Idiopathic Dilated Cardiomyopathy

Dilated Cardiomyopathy

Drug: Benazepril;Drug: Valsartan;Drug: Metoprolol

Xijing Hospital

NULL

Completed

18 Years

70 Years

Both

480

Phase 4

China

NCT01798992
(ClinicalTrials.gov)

September 2000

22/2/2013

Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart

Beta-blocker Effect on Structural Remodeling and Gene Expression in the Failing Human Heart

Idiopathic Dilated Cardiomyopathy

Drug: Carvedilol;Drug: Metoprolol succinate;Drug: Metoprolol succinate + doxazosin

University of Colorado, Denver

National Heart, Lung, and Blood Institute (NHLBI);GlaxoSmithKline;AstraZeneca

Completed

18 Years

N/A

All

Phase 4

United States