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Timolol    (DrugBank: Timolol)

2 diseases
告示番号疾患名（ページ内リンク）臨床試験数
157スタージ・ウェーバー症候群1
227オスラー病4

157. スタージ・ウェーバー症候群　［臨床試験数：8，薬物数：11（DrugBank：4），標的遺伝子数：5，標的パスウェイ数：62］
Searched query = "Sturge-Weber syndrome", "Síndrome de Sturge-Weber"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 8 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT01533376
(ClinicalTrials.gov)		February 201211/2/2012Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical TimololTreatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical TimololSturge Weber Syndrome;Port-wine MarkDrug: Timolol;Drug: Preservative free artificial tear gel.Wills EyeUniversity of Medicine and Dentistry of New JerseyTerminated2 Years10 YearsAll3Phase 1United States

227. オスラー病　［臨床試験数：49，薬物数：69（DrugBank：21），標的遺伝子数：23，標的パスウェイ数：132］
Searched query = "Osler disease", "Hereditary hemorrhagic telangiectasia", "Osler-Weber-Rendu disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
4 / 49 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT04139018
(ClinicalTrials.gov)		October 20, 201923/10/2019Timolol Gel for Epistaxis in Hereditary Hemorrhagic TelangiectasiaEfficacy of a Timolol Gel in the Care for Epistaxis in Patients With Hereditary Hemorrhagic Telangiectasia: A Double-Blinded, Randomized Controlled TrialHereditary Hemorrhagic TelangiectasiaDrug: Timolol Gel;Drug: Placebo GelWashington University School of MedicineNULLRecruiting20 YearsN/AAll30Phase 2United States
2NCT02484716
(ClinicalTrials.gov)		June 201517/6/2015Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - (TEMPO)Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - Randomized Trial Versus PlaceboHemorrhagic Hereditary Telangiectasia (HHT)Drug: Timolol nasal spray;Drug: Placebo nasal sprayHospices Civils de LyonNULLCompleted18 YearsN/AAll58Phase 2France
3EUCTR2015-000385-55-FR
(EUCTR)		12/05/201529/03/2017Essai d’efficacité du timolol en spray nasal pour le traitement des épistaxis dans la maladie de Rendu-Osler.TEMPO : Efficacité du TIMOLOL en administration nasale pour le traitement des épistaxis dans la maladie de Rendu-Osler.Essai randomisé en double insu contre placebo - TEMPO Rendu-Osler disease
MedDRA version: 19.1;Level: LLT;Classification code 10031132;Term: Osler-Weber-Rendu disease;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]		Trade Name: Timolol Alcon 0.5% collyre
Other descriptive name: TIMOLOL MALEATE		Hospices Civils de LyonNULLNot RecruitingFemale: yes
Male: yes		58Phase 2France
4NCT01752049
(ClinicalTrials.gov)		May 201314/12/2012Topical Anti-angiogenic Therapy for Telangiectasia in HHT: Proof of ConceptTopical Anti-angiogenic Therapy for Telangiectasia in HHT: Proof of ConceptHereditary Hemorrhagic TelangiectasiaDrug: Topical timolol maleate;Drug: placebo saline dropsSt. Michael's Hospital, TorontoUniversity of California, San Francisco;The Hospital for Sick Children;University of Toronto;Sunnybrook Health Sciences Centre;Ryerson University;National Institute of Neurological Disorders and Stroke (NINDS)Completed18 YearsN/AAll5N/ACanada

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