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Atenolol    (DrugBank: Atenolol)

1 disease
告示番号疾患名（ページ内リンク）臨床試験数
167マルファン症候群9

167. マルファン症候群　［臨床試験数：19，薬物数：38（DrugBank：10），標的遺伝子数：10，標的パスウェイ数：49］
Searched query = "Marfan syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
9 / 19 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT01715207
(ClinicalTrials.gov)		June 201024/10/2012Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFSComparison Study of the Effect of Aliskiren Versus Negative Controls on Aortic Stiffness in Patients With Marfan Syndrome Under Treatment With AtenololMarfan SyndromeDrug: Aliskiren;Drug: AtenololSamsung Medical CenterNULLCompleted14 Years55 YearsAll30Phase 3Korea, Republic of
2NCT01145612
(ClinicalTrials.gov)		October 200815/6/2010Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan SyndromeA Clinical Trial to Assess the Efficacy and Safety of Losartan Versus Atenolol in the Prevention of Progressive Dilation of the Aorta in Patients With Marfan Syndrome.Marfan SyndromeDrug: Losartan;Drug: AtenololForteza, Albert, M.D.Ministry of Health, SpainActive, not recruiting5 Years60 YearsBoth140Phase 3Spain
3EUCTR2007-001125-97-ES
(EUCTR)		20/05/200803/12/2007Eficacia y Seguridad de Losartán vs Atenolol en la prevención de la dilatación progresiva de la aorta en la población de pacientes con Síndrome de Marfan (Losartan vs atenolol efficacy and security in aortic dilatation prevention in Marfan syndrome)Eficacia y Seguridad de Losartán vs Atenolol en la prevención de la dilatación progresiva de la aorta en la población de pacientes con Síndrome de Marfan (Losartan vs atenolol efficacy and security in aortic dilatation prevention in Marfan syndrome) The aortic dilatation in Marfan syndrome with two different treatments: losartan vs atenolol
MedDRA version: 9.1;Level: LLT;Classification code 10026829;Term: Marfan's syndrome		Trade Name: cozaar 50
INN or Proposed INN: LOSARTAN POTASSIUM
Trade Name: blokium 50
INN or Proposed INN: ATENOLOL
Trade Name: COZAAR INICIO 12,5 mg comprimidos recubiertos con pelicula
INN or Proposed INN: LOSARTAN POTASSIUM
Trade Name: BLOKIUM 50 mg comprimidos
INN or Proposed INN: ATENOLOL		alberto fortezaNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes		Spain
4NCT00593710
(ClinicalTrials.gov)		January 20083/1/2008Losartan Versus Atenolol for the Treatment of Marfan SyndromeA Randomized Double-blind Study Assessing the Effects of Losartan Versus Atenolol on Pulse Wave Velocity and the Biophysical Properties of the Aorta in Patients With Marfan SyndromeMarfan SyndromeDrug: Losartan;Drug: AtenololUniversity of British ColumbiaHeart and Stroke Foundation of CanadaCompleted12 Years25 YearsBoth17Phase 2Canada
5NCT00723801
(ClinicalTrials.gov)		October 200725/7/2008Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan SyndromeEffects of Losartan vs Atenolol on Aortic Stiffness and Diastolic Function in Adults With Marfan SyndromeMarfan SyndromeDrug: Atenolol;Drug: LosartanBrigham and Women's HospitalBoston Children’s HospitalCompleted25 YearsN/AAll40Phase 3United States
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
6NCT00651235
(ClinicalTrials.gov)		February 20073/3/2008A Randomized, Open-label, LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan SyndromeA Randomized, Open-label, Active Control Trial to Evaluate the Effect of LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan SyndromeMarfan SyndromeDrug: Losartan and Atenolol or Propranolol;Drug: Atenolol or PropranololNational Taiwan University HospitalNULLRecruiting1 YearN/ABoth44Phase 2Taiwan
7NCT00429364
(ClinicalTrials.gov)		January 200729/1/2007Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome--Pediatric Heart NetworkTrial of Beta Blocker Therapy (Atenolol) Versus Angiotensin II Receptor Blocker Therapy (Losartan) in Individuals With Marfan Syndrome (A Trial Conducted by the Pediatric Heart Network)Marfan SyndromeDrug: Losartan Potassium;Drug: AtenololNew England Research InstitutesNational Heart, Lung, and Blood Institute (NHLBI);FDA Office of Orphan Products Development;National Marfan FoundationCompleted6 Months25 YearsAll608Phase 3United States;Belgium;Canada
8EUCTR2006-003991-37-BE
(EUCTR)		13/12/200606/12/2006Trial of beta blocker therapy (atenolol) vs. angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndrome - Marfan TrialTrial of beta blocker therapy (atenolol) vs. angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndrome - Marfan Trial Marfan syndrome
MedDRA version: 8.1;Level: LLT;Classification code 10026829;Term: Marfan's syndrome		Product Name: losartan
INN or Proposed INN: Losartan potassium
Product Name: losartan
INN or Proposed INN: Losartan potassium
Product Name: losartan
INN or Proposed INN: Losartan potassium
Product Name: Atenolol
INN or Proposed INN: Atenolol
Product Name: Atenolol
INN or Proposed INN: Atenolol
Product Name: Atenolol
INN or Proposed INN: Atenolol		University Hospital GentNULLNot RecruitingFemale: yes
Male: yes		600Belgium
9NCT01295047
(ClinicalTrials.gov)		July 200611/2/2011Comparison of Medical Therapies in Marfan Syndrome.Effects of Atenolol, Perindopril and Verapamil on Haemodynamic and Vascular Function in Marfan Syndrome - A Randomised Double-Blind Crossover TrialMarfan SyndromeDrug: Atenolol;Drug: VERAPAMIL;Drug: PerindoprilCardiff UniversityNULLCompleted16 Years60 YearsBoth18Phase 4United Kingdom

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