DDrare: Database of Drug Development for Rare Diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
2	筋萎縮性側索硬化症	2

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02962050 (ClinicalTrials.gov)	May 31, 2017	4/11/2016	Delineating Swallowing Impairment and Decline in ALS	Delineating Physiologic Mechanisms of Swallowing Impairment and Decline in ALS	Amyotrophic Lateral Sclerosis	Procedure: Videofluoroscopic Swallowing Study (VFSS);Device: Voluntary Peak Cough Flow Testing;Device: Iowa Oral Performance Instrument;Drug: Capsaicin Challenge;Device: Pulmonary Function Testing;Other: Eating Assessment Tool 10;Other: The Center for Neurologic Study Bulbar Function Scale	University of Florida	National Institute of Neurological Disorders and Stroke (NINDS)	Recruiting	18 Years	90 Years	All	110		United States
2	NCT02710162 (ClinicalTrials.gov)	April 2016	29/2/2016	Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)	Determination of Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)	Amyotrophic Lateral Sclerosis	Device: Micro Mouth Pressure Meter;Device: Iowa Oral Performance Instrument;Device: Electrical Impedance Myography;Drug: Capsaicin;Procedure: Videofluoroscopic Swallowing Study;Procedure: Pulmonary Function Testing;Other: Swallowing Related Quality of Life Questionnaire;Other: Functional Oral Intake Scale;Other: Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised;Other: Eating Assessment Tool-10;Other: Communicative Effectiveness Survey;Other: The Center for Neurologic Studies Bulbar Function Scale	University of Florida	NULL	Completed	21 Years	85 Years	All	21	Early Phase 1	United States

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT02962050
(ClinicalTrials.gov)

May 31, 2017

4/11/2016

Delineating Swallowing Impairment and Decline in ALS

Delineating Physiologic Mechanisms of Swallowing Impairment and Decline in ALS

Amyotrophic Lateral Sclerosis

Procedure: Videofluoroscopic Swallowing Study (VFSS);Device: Voluntary Peak Cough Flow Testing;Device: Iowa Oral Performance Instrument;Drug: Capsaicin Challenge;Device: Pulmonary Function Testing;Other: Eating Assessment Tool 10;Other: The Center for Neurologic Study Bulbar Function Scale

University of Florida

National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

18 Years

90 Years

All

110

United States

NCT02710162
(ClinicalTrials.gov)

April 2016

29/2/2016

Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)

Determination of Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Device: Micro Mouth Pressure Meter;Device: Iowa Oral Performance Instrument;Device: Electrical Impedance Myography;Drug: Capsaicin;Procedure: Videofluoroscopic Swallowing Study;Procedure: Pulmonary Function Testing;Other: Swallowing Related Quality of Life Questionnaire;Other: Functional Oral Intake Scale;Other: Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised;Other: Eating Assessment Tool-10;Other: Communicative Effectiveness Survey;Other: The Center for Neurologic Studies Bulbar Function Scale

University of Florida

NULL

Completed

21 Years

85 Years

All

Early Phase 1

United States