Tocilizumab plus methotrexate (DrugBank: Methotrexate, Tocilizumab)
1 disease| 告示番号 | 疾患名（ページ内リンク） | 臨床試験数 |
|---|---|---|
| 46 | 悪性関節リウマチ | 4 |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | JPRN-UMIN000015616 | 2014/11/04 | 10/11/2014 | Biologic MateR clinical performance test for ADA and TCZ Efficacy prediction | rheumatoid arthritis | Adalimumab plus Methotrexate Tocilizumab plus Methotrexate | Biologic Mate Study Group | NULL | Complete: follow-up complete | 20years-old | 75years-old | Male and Female | 300 | Not selected | Japan | |
| 2 | JPRN-UMIN000002744 | 2009/11/01 | 10/11/2009 | Success of tocilizumab in RA patients with remission induction and sustained efficacy after discontinuation | rheumatoid arthritis | tocilizumab plus methotrexate tocilizumab | Keio University | NULL | Complete: follow-up complete | 20years-old | 75years-old | Male and Female | 300 | Not selected | Japan | |
| 3 | NCT01120366 (ClinicalTrials.gov) | October 2009 | 6/5/2010 | Success of Tocilizumab in RA Patients With Remission Induction and Sustained Efficacy After Discontinuation | Success of Tocilizumab in RA Patients With Remission Induction and Sustained Efficacy After Discontinuation | Rheumatoid Arthritis | Drug: Tocilizumab plus methotrexate;Drug: Tocilizumab | SURPRISE Study Group | NULL | Completed | 20 Years | 75 Years | Both | 233 | Phase 4 | Japan |
| 4 | NCT00754572 (ClinicalTrials.gov) | February 2009 | 17/9/2008 | A Study to Assess the Effect of Tocilizumab Plus Methotrexate on Safety and Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis | A Single-arm, Open-label Study of the Safety and Reduction of Signs and Symptoms During Treatment With Tocilizumab in Combination With Methotrexate, in Patients With Moderate to Severe Active Rheumatoid Arthritis | Rheumatoid Arthritis | Drug: tocilizumab [RoActemra/Actemra];Drug: methotrexate | Hoffmann-La Roche | NULL | Completed | 18 Years | N/A | All | 418 | Phase 3 | Argentina;Brazil;Chile;Colombia;Costa Rica;Ecuador;Mexico;Peru;Uruguay;Venezuela |