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 Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト） 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"

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201 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES *   KEGG DRUG *   DrugBank   指定難病告示番号 * 
 1  Acute myeloid leukemia 
 3 genes, 4 drugs (DrugBank) and 40 diseases shown 		  1件: KIT   D10229   Masitinib   6件: 2, 5, 6, 13, 46, 96 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: RARA   D01418   Tamibarotene   2件: 26, 96 
 2  Adherens junction 
 2 genes, 2 drugs (DrugBank) and 7 diseases shown 		  1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 1件: INSR   D00085   Insulin Human   2件: 96, 156 
 D03230 
 3  Adipocytokine signaling pathway 
 3 genes, 9 drugs (DrugBank) and 68 diseases shown 		  1件: JAK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 4  Adrenergic signaling in cardiomyocytes 
 11 genes, 4 drugs (DrugBank) and 29 diseases shown 		  5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 1件: SCN5A   D01450   Bupivacaine   7件: 46, 53, 70, 96, 168, 226, 298 
 D07552 
 5  African trypanosomiasis 
 3 genes, 7 drugs (DrugBank) and 45 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 6  AGE-RAGE signaling pathway in diabetic complications 
 3 genes, 8 drugs (DrugBank) and 54 diseases shown 		  1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 1件: JAK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 7  Alcoholism 
 18 genes, 4 drugs (DrugBank) and 10 diseases shown 		  1件: ADORA2A   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9   D06320   Vorinostat   2件: 19, 96 
 1件: SLC6A3   D00817   Bupropion   2件: 8, 96 
 D07591 
 D07938 
 8  Aldosterone synthesis and secretion 
 6 genes, 3 drugs (DrugBank) and 23 diseases shown 		  1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 1件: PDE2A   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 9  Aldosterone-regulated sodium reabsorption 
 1 gene, 1 drug (DrugBank) and 2 diseases shown 		  1件: INSR   D00085   Insulin Human   2件: 96, 156 
 D03230 
 10  Allograft rejection 
 25 genes, 9 drugs (DrugBank) and 52 diseases shown 		  2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G   D04318   Glatiramer   4件: 2, 13, 96, 156 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 11  Alzheimer disease 
 15 genes, 9 drugs (DrugBank) and 64 diseases shown 		  4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 12  Amoebiasis 
 3 genes, 7 drugs (DrugBank) and 45 diseases shown 		  2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 13  Amphetamine addiction 
 15 genes, 5 drugs (DrugBank) and 38 diseases shown 		  2件: CACNA1C, CACNA1D   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 2件: HDAC1, HDAC2   D06320   Vorinostat   2件: 19, 96 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: SLC6A3   D00817   Bupropion   2件: 8, 96 
 D07591 
 D07938 
 14  AMPK signaling pathway 
 6 genes, 9 drugs (DrugBank) and 59 diseases shown 		  1件: ADRA1A   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: HMGCR   D00887   Atorvastatin   17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 
 D07474 
 D00893   Pravastatin   9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 
 D08410 
 D01915   Rosuvastatin   8件: 6, 46, 49, 51, 79, 96, 271, 299 
 D08492 
 1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 1件: INSR   D00085   Insulin Human   2件: 96, 156 
 D03230 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: PPARG   D00945   Pioglitazone   17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 15  Amyotrophic lateral sclerosis (ALS) 
 11 genes, 8 drugs (DrugBank) and 61 diseases shown 		  5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 16  Antifolate resistance 
 3 genes, 7 drugs (DrugBank) and 55 diseases shown 		  2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 17  Antigen processing and presentation 
 21 genes, 7 drugs (DrugBank) and 45 diseases shown 		  20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G   D04318   Glatiramer   4件: 2, 13, 96, 156 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 18  Apelin signaling pathway 
 5 genes, 5 drugs (DrugBank) and 48 diseases shown 		  1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 2件: HDAC4, HDAC5   D06320   Vorinostat   2件: 19, 96 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: PDE3B   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 19  Apoptosis 
 1 gene, 6 drugs (DrugBank) and 43 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 20  Arachidonic acid metabolism 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 		  1件: PTGS2   D00567   Celecoxib   9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 
 21  Arrhythmogenic right ventricular cardiomyopathy (ARVC) 
 6 genes, 4 drugs (DrugBank) and 10 diseases shown 		  4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 1件: ITGA4   D06886   Natalizumab   6件: 13, 15, 25, 46, 63, 96 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 22  Asthma 
 15 genes, 7 drugs (DrugBank) and 45 diseases shown 		  14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5   D04318   Glatiramer   4件: 2, 13, 96, 156 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 23  Autoimmune thyroid disease 
 23 genes, 3 drugs (DrugBank) and 26 diseases shown 		  2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: CTLA4   D06657   Tremelimumab   2件: 65, 96 
 20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G   D04318   Glatiramer   4件: 2, 13, 96, 156 
 24  Autophagy - animal 
 2 genes, 3 drugs (DrugBank) and 41 diseases shown 		  1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 25  Autophagy - other 
 1 gene, 2 drugs (DrugBank) and 37 diseases shown 		  1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 26  Axon guidance 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 27  B cell receptor signaling pathway 
 5 genes, 1 drug (DrugBank) and 30 diseases shown 		  5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 28  Bile secretion 
 2 genes, 5 drugs (DrugBank) and 28 diseases shown 		  1件: HMGCR   D00887   Atorvastatin   17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 
 D07474 
 D00893   Pravastatin   9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 
 D08410 
 D01915   Rosuvastatin   8件: 6, 46, 49, 51, 79, 96, 271, 299 
 D08492 
 1件: NR1H4   D00163   Chenodeoxycholic acid   4件: 20, 96, 234, 263 
 D00734   Ursodeoxycholic acid   12件: 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 299 
 29  Breast cancer 
 6 genes, 6 drugs (DrugBank) and 50 diseases shown 		  2件: ESR1, ESR2   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 1件: KIT   D10229   Masitinib   6件: 2, 5, 6, 13, 46, 96 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: TNFSF11   D03684   Denosumab   7件: 46, 50, 93, 95, 96, 274, 299 
 30  C-type lectin receptor signaling pathway 
 10 genes, 12 drugs (DrugBank) and 62 diseases shown 		  3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL23A   D10438   Guselkumab   3件: 37, 96, 97 
 D11123   Mirikizumab   2件: 96, 97 
 D11052   Risankizumab   4件: 37, 96, 97, 271 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: PTGS2   D00567   Celecoxib   9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 31  Caffeine metabolism 
 1 gene, 1 drug (DrugBank) and 6 diseases shown 		  1件: XDH   D00224   Allopurinol   6件: 6, 46, 57, 66, 96, 97 
 32  Calcium signaling pathway 
 24 genes, 9 drugs (DrugBank) and 47 diseases shown 		  2件: ADORA2A, PDE1B   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 1件: HRH1   D00480   Promethazine   1件: 96 
 D00494 
 D01242 
 D03290 
 1件: HTR4   D08236   Mosapride   1件: 96 
 D09205   Prucalopride   3件: 13, 51, 96 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 33  cAMP signaling pathway 
 21 genes, 7 drugs (DrugBank) and 25 diseases shown 		  8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 2件: ADRB1, ADRB2   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 1件: HTR4   D08236   Mosapride   1件: 96 
 D09205   Prucalopride   3件: 13, 51, 96 
 1件: SSTR2   D00442   Octreotide   8件: 67, 75, 84, 85, 89, 96, 193, 227 
 D06495 
 34  Carbohydrate digestion and absorption 
 1 gene, 1 drug (DrugBank) and 4 diseases shown 		  1件: CACNA1D   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 35  Cardiac muscle contraction 
 4 genes, 1 drug (DrugBank) and 4 diseases shown 		  4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 36  Cell adhesion molecules (CAMs) 
 27 genes, 8 drugs (DrugBank) and 33 diseases shown 		  2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 1件: CTLA4   D06657   Tremelimumab   2件: 65, 96 
 20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G   D04318   Glatiramer   4件: 2, 13, 96, 156 
 1件: ITGA4   D06886   Natalizumab   6件: 13, 15, 25, 46, 63, 96 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGAL   D03959   Efalizumab   9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 1件: PDCD1   D10316   Nivolumab   10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 
 37  Cell cycle 
 2 genes, 1 drug (DrugBank) and 2 diseases shown 		  2件: HDAC1, HDAC2   D06320   Vorinostat   2件: 19, 96 
 38  Cellular senescence 
 13 genes, 5 drugs (DrugBank) and 53 diseases shown 		  1件: CACNA1D   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G   D04318   Glatiramer   4件: 2, 13, 96, 156 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 39  Central carbon metabolism in cancer 
 2 genes, 3 drugs (DrugBank) and 39 diseases shown 		  1件: KIT   D10229   Masitinib   6件: 2, 5, 6, 13, 46, 96 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 40  cGMP-PKG signaling pathway 
 26 genes, 8 drugs (DrugBank) and 59 diseases shown 		  5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 1件: INSR   D00085   Insulin Human   2件: 96, 156 
 D03230 
 1件: OPRD1   D02095   Naltrexone   11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 
 D05113 
 1件: PDE5A   D02229   Sildenafil   16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 
 D08514 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 41  Chagas disease (American trypanosomiasis) 
 6 genes, 9 drugs (DrugBank) and 46 diseases shown 		  3件: CD3D, CD3E, CD3G   D05092   Muromonab   3件: 60, 96, 97 
 D06314   Visilizumab   2件: 96, 97 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 42  Chemical carcinogenesis 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 		  1件: PTGS2   D00567   Celecoxib   9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 
 43  Chemokine signaling pathway 
 2 genes, 1 drug (DrugBank) and 9 diseases shown 		  2件: JAK2, JAK3   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 44  Choline metabolism in cancer 
 1 gene, 2 drugs (DrugBank) and 37 diseases shown 		  1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 45  Cholinergic synapse 
 5 genes, 2 drugs (DrugBank) and 12 diseases shown 		  4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 1件: JAK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 46  Chronic myeloid leukemia 
 2 genes, 1 drug (DrugBank) and 2 diseases shown 		  2件: HDAC1, HDAC2   D06320   Vorinostat   2件: 19, 96 
 47  Circadian entrainment 
 7 genes, 2 drugs (DrugBank) and 12 diseases shown 		  2件: CACNA1C, CACNA1D   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 48  Cocaine addiction 
 6 genes, 2 drugs (DrugBank) and 9 diseases shown 		  5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 1件: SLC6A3   D00817   Bupropion   2件: 8, 96 
 D07591 
 D07938 
 49  Collecting duct acid secretion 
 2 genes, 1 drug (DrugBank) and 15 diseases shown 		  2件: ATP4A, ATP4B   D00455   Omeprazole   15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 50  Colorectal cancer 
 1 gene, 2 drugs (DrugBank) and 37 diseases shown 		  1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 51  Complement and coagulation cascades 
 1 gene, 1 drug (DrugBank) and 2 diseases shown 		  1件: F10   D03213   Apixaban   2件: 96, 97 
 52  Cortisol synthesis and secretion 
 5 genes, 2 drugs (DrugBank) and 20 diseases shown 		  1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 53  Cushing syndrome 
 5 genes, 2 drugs (DrugBank) and 20 diseases shown 		  1件: AGTR1   D00357   Losartan   18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 54  Cytokine-cytokine receptor interaction 
 12 genes, 19 drugs (DrugBank) and 73 diseases shown 		  1件: CSF2RA   D05803   Sargramostim   6件: 6, 28, 60, 62, 96, 229 
 1件: CSF3R   D03235   Filgrastim   28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 1件: EPOR   D03231   Erythropoietin   9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 
 1件: GHR   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 D02691   Somatotropin   18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 1件: IL11RA   D05266   Oprelvekin   2件: 96, 288 
 3件: IL12A, IL12B, IL23A   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: IL23A   D10438   Guselkumab   3件: 37, 96, 97 
 D11123   Mirikizumab   2件: 96, 97 
 D11052   Risankizumab   4件: 37, 96, 97, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 1件: TNFSF11   D03684   Denosumab   7件: 46, 50, 93, 95, 96, 274, 299 
 55  Dilated cardiomyopathy (DCM) 
 8 genes, 11 drugs (DrugBank) and 55 diseases shown 		  1件: ADRB1   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 1件: ITGA4   D06886   Natalizumab   6件: 13, 15, 25, 46, 63, 96 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 56  DNA replication 
 2 genes, 1 drug (DrugBank) and 9 diseases shown 		  2件: POLA1, POLA2   D03546   Clofarabine   9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 
 57  Dopaminergic synapse 
 9 genes, 5 drugs (DrugBank) and 40 diseases shown 		  2件: CACNA1C, CACNA1D   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 2件: GRIN2A, GRIN2B   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 3件: PPP3CA, PPP3CB, PPP3CC   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 1件: SCN1A   D01450   Bupivacaine   7件: 46, 53, 70, 96, 168, 226, 298 
 D07552 
 1件: SLC6A3   D00817   Bupropion   2件: 8, 96 
 D07591 
 D07938 
 58  Drug metabolism - other enzymes 
 5 genes, 6 drugs (DrugBank) and 43 diseases shown 		  1件: HPRT1   D00161   Mercaptopurine   5件: 86, 94, 96, 97, 164 
 D04931 
 2件: IMPDH1, IMPDH2   D00752   Mycophenolate mofetil   32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 1件: RRM1   D03546   Clofarabine   9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 
 D01907   Fludarabine   17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 1件: XDH   D00224   Allopurinol   6件: 6, 46, 57, 66, 96, 97 
 59  ECM-receptor interaction 
 2 genes, 3 drugs (DrugBank) and 7 diseases shown 		  1件: ITGA4   D06886   Natalizumab   6件: 13, 15, 25, 46, 63, 96 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 60  EGFR tyrosine kinase inhibitor resistance 
 4 genes, 6 drugs (DrugBank) and 48 diseases shown 		  1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 2件: JAK1, JAK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 61  Endocrine and other factor-regulated calcium reabsorption 
 2 genes, 5 drugs (DrugBank) and 26 diseases shown 		  1件: ESR1   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 1件: VDR   D01518   Alfacalcidol   6件: 41, 46, 49, 50, 96, 235 
 D00129   Calcitriol   8件: 37, 46, 49, 66, 96, 158, 235, 326 
 D00188   Cholecalciferol   15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 
 D00187   Ergocalciferol   5件: 46, 84, 96, 97, 299 
 62  Endocrine resistance 
 4 genes, 4 drugs (DrugBank) and 44 diseases shown 		  2件: ESR1, ESR2   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 63  Endocytosis 
 7 genes, 2 drugs (DrugBank) and 9 diseases shown 		  6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G   D04318   Glatiramer   4件: 2, 13, 96, 156 
 1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 64  Epstein-Barr virus infection 
 32 genes, 16 drugs (DrugBank) and 51 diseases shown 		  3件: CD3D, CD3E, CD3G   D05092   Muromonab   3件: 60, 96, 97 
 D06314   Visilizumab   2件: 96, 97 
 2件: HDAC1, HDAC2   D06320   Vorinostat   2件: 19, 96 
 20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G   D04318   Glatiramer   4件: 2, 13, 96, 156 
 2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 1件: ITGAL   D03959   Efalizumab   9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 3件: JAK1, JAK3, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 65  ErbB signaling pathway 
 1 gene, 2 drugs (DrugBank) and 37 diseases shown 		  1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 66  Estrogen signaling pathway 
 4 genes, 3 drugs (DrugBank) and 17 diseases shown 		  2件: ESR1, ESR2   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 1件: OPRM1   D02095   Naltrexone   11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 
 D05113 
 1件: RARA   D01418   Tamibarotene   2件: 26, 96 
 67  Fc epsilon RI signaling pathway 
 1 gene, 6 drugs (DrugBank) and 43 diseases shown 		  1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 68  Fluid shear stress and atherosclerosis 
 2 genes, 7 drugs (DrugBank) and 48 diseases shown 		  1件: NQO1   D00564   Warfarin   10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 
 D01280 
 D08682 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 69  Focal adhesion 
 3 genes, 4 drugs (DrugBank) and 12 diseases shown 		  1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 1件: ITGA4   D06886   Natalizumab   6件: 13, 15, 25, 46, 63, 96 
 2件: ITGA4, ITGB7   D08083   Vedolizumab   2件: 96, 97 
 1件: ITGB7   D09901   Etrolizumab   2件: 96, 97 
 70  Folate biosynthesis 
 2 genes, 1 drug (DrugBank) and 33 diseases shown 		  2件: DHFR, DHFR2   D00142   Methotrexate   33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 71  FoxO signaling pathway 
 4 genes, 3 drugs (DrugBank) and 9 diseases shown 		  1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 1件: INSR   D00085   Insulin Human   2件: 96, 156 
 D03230 
 2件: S1PR1, S1PR4   D10968   Ozanimod   3件: 13, 96, 97 
 72  GABAergic synapse 
 20 genes, 2 drugs (DrugBank) and 13 diseases shown 		  4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00550   Midazolam   10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 73  Gap junction 
 1 gene, 1 drug (DrugBank) and 9 diseases shown 		  1件: ADRB1   D00095   Epinephrine   9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 
 D00996 
 D02149 
 74  Gastric acid secretion 
 3 genes, 2 drugs (DrugBank) and 21 diseases shown 		  2件: ATP4A, ATP4B   D00455   Omeprazole   15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 1件: SSTR2   D00442   Octreotide   8件: 67, 75, 84, 85, 89, 96, 193, 227 
 D06495 
 75  Gastric cancer 
 1 gene, 2 drugs (DrugBank) and 37 diseases shown 		  1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 76  Glioma 
 2 genes, 3 drugs (DrugBank) and 41 diseases shown 		  1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 77  Glucagon signaling pathway 
 6 genes, 2 drugs (DrugBank) and 32 diseases shown 		  1件: PDE3B   D00528   Caffeine   6件: 2, 6, 46, 78, 96, 97 
 D01453 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 78  Glutamatergic synapse 
 12 genes, 3 drugs (DrugBank) and 37 diseases shown 		  2件: CACNA1C, CACNA1D   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00848   Dextromethorphan   9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 
 D03742 
 D03744 
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00107   Tacrolimus   30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 
 D08556 
 79  Glutathione metabolism 
 1 gene, 2 drugs (DrugBank) and 21 diseases shown 		  1件: RRM1   D03546   Clofarabine   9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 
 D01907   Fludarabine   17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 80  GnRH secretion 
 5 genes, 2 drugs (DrugBank) and 9 diseases shown 		  4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 1件: ESR2   D08409   Prasterone   6件: 49, 53, 83, 86, 96, 113 
 81  GnRH signaling pathway 
 4 genes, 1 drug (DrugBank) and 4 diseases shown 		  4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 82  Graft-versus-host disease 
 23 genes, 8 drugs (DrugBank) and 52 diseases shown 		  2件: CD80, CD86   D03203   Abatacept   24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G   D04318   Glatiramer   4件: 2, 13, 96, 156 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 83  Growth hormone synthesis, secretion and action 
 8 genes, 7 drugs (DrugBank) and 61 diseases shown 		  4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00619   Verapamil   4件: 96, 130, 140, 167 
 D02356 
 1件: GHR   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 D02691   Somatotropin   18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 1件: JAK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: SSTR2   D00442   Octreotide   8件: 67, 75, 84, 85, 89, 96, 193, 227 
 D06495 
 84  Hematopoietic cell lineage 
 25 genes, 17 drugs (DrugBank) and 75 diseases shown 		  3件: CD3D, CD3E, CD3G   D05092   Muromonab   3件: 60, 96, 97 
 D06314   Visilizumab   2件: 96, 97 
 1件: CSF2RA   D05803   Sargramostim   6件: 6, 28, 60, 62, 96, 229 
 1件: CSF3R   D03235   Filgrastim   28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 1件: EPOR   D03231   Erythropoietin   9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 
 14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5   D04318   Glatiramer   4件: 2, 13, 96, 156 
 1件: IL11RA   D05266   Oprelvekin   2件: 96, 288 
 1件: ITGA4   D06886   Natalizumab   6件: 13, 15, 25, 46, 63, 96 
 D08083   Vedolizumab   2件: 96, 97 
 1件: KIT   D10229   Masitinib   6件: 2, 5, 6, 13, 46, 96 
 1件: MS4A1   D02994   Rituximab   42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 85  Hepatitis B 
 6 genes, 11 drugs (DrugBank) and 47 diseases shown 		  1件: IFNAR1   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 4件: JAK1, JAK2, JAK3, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 86  Hepatitis C 
 5 genes, 11 drugs (DrugBank) and 47 diseases shown 		  2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 2件: JAK1, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 87  Hepatocellular carcinoma 
 3 genes, 4 drugs (DrugBank) and 45 diseases shown 		  1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: NQO1   D00564   Warfarin   10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 
 D01280 
 D08682 
 88  Herpes simplex virus 1 infection 
 29 genes, 15 drugs (DrugBank) and 72 diseases shown 		  20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G   D04318   Glatiramer   4件: 2, 13, 96, 156 
 2件: IFNAR1, IFNAR2   D03305   Interferon alfa   5件: 25, 26, 28, 56, 96 
 D04554   Interferon beta-1a   5件: 13, 14, 26, 96, 97 
 2件: IL12A, IL12B   D09214   Ustekinumab   16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 1件: JAK1   D10871   Filgotinib   6件: 46, 53, 96, 97, 222, 271 
 D10994   Upadacitinib   6件: 41, 46, 49, 96, 97, 271 
 3件: JAK1, JAK2, TYK2   D09970   Tofacitinib   9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 
 1件: MTOR   D02714   Everolimus   9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 
 D00753   Sirolimus   36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 1件: TNF   D02597   Adalimumab   15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 D03441   Certolizumab pegol   6件: 37, 46, 96, 97, 226, 271 
 D04358   Golimumab   5件: 46, 84, 96, 97, 271 
 D02598   Infliximab   23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 D04687   Lenalidomide   8件: 16, 26, 28, 34, 49, 96, 284, 300 
 D00754   Thalidomide   18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 89  HIF-1 signaling pathway 
 3 genes, 4 drugs (DrugBank) and 42 diseases shown 		  1件: IGF1R   D03297   Mecasermin   6件: 65, 78, 96, 168, 265, 299 
 D04870 
 1件: INSR   D00085   Insulin Human   2件: 96, 156 
 D03230 
 1件: MTOR