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No. 薬物名(臨床試験情報から抽出) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
11639325-43-11件: Givosiran1件: D11702 1件: ALAS1 💬4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
25-probe cocktail1件: Givosiran1件: D11702 1件: ALAS1 💬4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
3[MT-7117]----2件: 51, 254
4[Nle4,D-Phe7]-a-melanocyte stimulating hormone or NDP-a-MSH1件: Afamelanotide1件: D10511 1件: MC1R 💬2件: Melanogenesis, Neuroactive ligand-receptor interaction 💬1件: 254
5A novel synthetic, orally-administered, non-peptide small molecule, which acts as----1件: 254
6AFAMELANOTIDE1件: Afamelanotide1件: D10511 1件: MC1R 💬2件: Melanogenesis, Neuroactive ligand-receptor interaction 💬2件: 159, 254
7Afamelanotide Implant1件: Afamelanotide1件: D10511 1件: MC1R 💬2件: Melanogenesis, Neuroactive ligand-receptor interaction 💬1件: 254
8ALN-605191件: Givosiran1件: D11702 1件: ALAS1 💬4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
9ALN-AS11件: Givosiran1件: D11702 1件: ALAS1 💬4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
10Aminolevulinic acid1件: Aminolevulinic acid2件: D02908 ,
D07567
--4件: 34, 96, 254, 286
11CAS # in D.3.9.1 for Sodium Salt. CAS number 1639325-43-1 (Parent Acid)1件: Givosiran1件: D11702 1件: ALAS1 💬4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
12CAS# in D.3.9.1 for Sodium Salt. CAS number 1639325-43-1 (Parent Acid)1件: Givosiran1件: D11702 1件: ALAS1 💬4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
13Chlorpromazine1件: Chlorpromazine4件: D00270 ,
D00789 ,
D03274 ,
D04034
13件: ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬
22件: Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 254
14Chlorpromazine Hydrochloride1件: Chlorpromazine4件: D00270 ,
D00789 ,
D03274 ,
D04034
13件: ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬
22件: Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 254
15Cimetidine1件: Cimetidine2件: D00295 ,
D03503
1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 2, 254
16Colestipol1件: Colestipol2件: D02113 ,
D07771
--1件: 254
17COLESTYRAMINE1件: Cholestyramine---1件: 254
18Concentration unit: mg milligram(s)1件: Afamelanotide1件: D10511 1件: MC1R 💬2件: Melanogenesis, Neuroactive ligand-receptor interaction 💬1件: 254
19CUV1647----1件: 254
20Cysteine1件: Cysteine2件: D00026 ,
D02326
--11件: 6, 13, 19, 34, 84, 85, 88, 90, 254, 296, 310
21Cysteine hydrochloride1件: Cysteine2件: D00026 ,
D02326
--1件: 254
22Deferasirox1件: Deferasirox1件: D03669 --3件: 254, 284, 286
23Dersimelagon----2件: 51, 254
24Exjade1件: Deferoxamine2件: D01186 ,
D03670
--3件: 254, 284, 286
25Givosiran1件: Givosiran1件: D11702 1件: ALAS1 💬4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
26Givosiran (ALN-AS1)1件: Givosiran1件: D11702 1件: ALAS1 💬4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
27Glucose1件: Arginine1件: D02982 --15件: 2, 6, 13, 49, 50, 65, 75, 86, 88, 96, 160, 195, 254, 257, 299
28Harvoni1件: Sofosbuvir1件: D10366 --1件: 254
29Heme arginate1件: Stannsoporfin1件: D05922 2件: HMOX1,
HMOX2 💬
10件: Chemical carcinogenesis - reactive oxygen species, Ferroptosis, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatocellular carcinoma, Metabolic pathways, MicroRNAs in cancer, Mineral absorption, Pathways in cancer, Porphyrin metabolism 💬1件: 254
30Hemin1件: Hemin1件: D10003 2件: ALAS1,
ALAS2 💬
4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
31Hemin for injection1件: Hemin1件: D10003 2件: ALAS1,
ALAS2 💬
4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
32Hydroxychloroquine1件: Prednisone1件: D00473 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
33Iron1件: Iron---6件: 18, 96, 97, 238, 254, 284
34Isoniazid1件: Isoniazid3件: D00346 ,
D01501 ,
D02002
--1件: 254
35Luteinizing hormone1件: Luteinizing hormone---1件: 254
36Luteinizing hormone-releasing factor1件: Luteinizing hormone---1件: 254
37MT-7117----2件: 51, 254
38MT-7117 High Dose----1件: 254
39MT-7117 Low Dose----1件: 254
40Nle4-D-Phe7-alpha-MSH----1件: 254
41Oral Iron1件: Iron---2件: 97, 254
42Other: Dosage of Delta-aminolevulinic acid and Porphobilinogen1件: Aminolevulinic acid2件: D02908 ,
D07567
--1件: 254
43Other: Glucose1件: Hemin1件: D10003 2件: ALAS1,
ALAS2 💬
4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
44Panhematin1件: Hemin1件: D10003 2件: ALAS1,
ALAS2 💬
4件: Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬1件: 254
45Phlebotomy1件: Hydroxychloroquine1件: D08050 --1件: 254
46Porphobilinogen1件: Aminolevulinic acid2件: D02908 ,
D07567
--1件: 254
47Questran1件: Cholestyramine---4件: 93, 254, 297, 338
48Recombinant human porphobilinogen deaminase (Porphozym)1件: Porphobilinogen---1件: 254
49SCENESSE1件: Afamelanotide1件: D10511 1件: MC1R 💬2件: Melanogenesis, Neuroactive ligand-receptor interaction 💬3件: 159, 161, 254
50Sterile Normal Saline (0.9% NaCl)----3件: 62, 234, 254
51Tin mesoporphyrin1件: Stannsoporfin1件: D05922 2件: HMOX1,
HMOX2 💬
10件: Chemical carcinogenesis - reactive oxygen species, Ferroptosis, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatocellular carcinoma, Metabolic pathways, MicroRNAs in cancer, Mineral absorption, Pathways in cancer, Porphyrin metabolism 💬1件: 254