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No. 薬物名(臨床試験情報から抽出) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1100 µg Brimonidine Tartrate Implant1件: Brimonidine2件: D02076 ,
D07540
3件: ADRA2A,
ADRA2B,
ADRA2C 💬
2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 90
2200 µg Brimonidine Tartrate Implant1件: Brimonidine2件: D02076 ,
D07540
3件: ADRA2A,
ADRA2B,
ADRA2C 💬
2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 90
3400 µg Brimonidine Tartrate Implant1件: Brimonidine2件: D02076 ,
D07540
3件: ADRA2A,
ADRA2B,
ADRA2C 💬
2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 90
44D-125 IVT Injection----1件: 90
59715X1件: Phosphatidyl serine1件: D04682 --1件: 90
69741X1件: Phosphatidyl serine1件: D04682 --1件: 90
79742X1件: Phosphatidyl serine1件: D04682 --1件: 90
8AAV-RPGR----1件: 90
9AAV2-REP11件: Timrepigene emparvovec---1件: 90
10AAV2/5-hPDE6B----1件: 90
11AAV2/5-hRKp.RPGR----1件: 90
12AAV5-HRKP.RPGR----1件: 90
13AAV8-RPGR1件: Timrepigene emparvovec---1件: 90
14Acetate1件: Benazepril2件: D00620 ,
D07499
1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬43件: 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
15Acetazolamide1件: Acetazolamide2件: D00218 ,
D01196
13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬
7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬6件: 13, 90, 115, 155, 225, 230
16Acetylcysteine1件: Pirfenidone1件: D01583 6件: CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬
84件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
17Adeno-associated virus type 2 vector encoding Rab escort protein 11件: Timrepigene emparvovec---1件: 90
18Aflibercept1件: Aflibercept1件: D09574 3件: PGF,
VEGFA,
VEGFB 💬
24件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬2件: 90, 166
19Alga Dunaliella Bardawil----1件: 90
20Alga Dunaliella Bardawil powder----1件: 90
21Alga Dunaliella Bardawill----1件: 90
22ALLOGENEIC NEURAL RETINA-DERIVED HUMAN NEURAL RETINAL PROGENITOR CELLS EX VIVO EXPANDED----1件: 90
23AlloRx----8件: 2, 6, 13, 46, 51, 85, 90, 226
24Antioxidants1件: Cholesterol1件: D00040 --3件: 90, 298, 310
25Betamethasone1件: Betamethasone7件: D00244 ,
D00972 ,
D01357 ,
D01402 ,
D01637 ,
D02032 ,
D02286
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬7件: 2, 28, 46, 83, 90, 96, 235
26BIIB112----1件: 90
27Blue light-absorbing sunglasses1件: Ginkgo biloba---1件: 90
28BMMNCs----1件: 90
29Botaretigene sparoparvovec----1件: 90
30Brimonidine1件: Brimonidine2件: D02076 ,
D07540
3件: ADRA2A,
ADRA2B,
ADRA2C 💬
2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬2件: 13, 90
31Brimonidine tartrate1件: Phosphatidyl serine1件: D04682 --2件: 13, 90
32Brimonidine Tartrate Posterior Segment Drug Delivery System (Brimo PS DDS) Applicator System1件: Phosphatidyl serine1件: D04682 --1件: 90
33BS01----1件: 90
34Cannabis1件: Medical Cannabis---9件: 2, 6, 13, 19, 46, 90, 96, 97, 271
35Carbidopa1件: Carbidopa1件: D00558 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬9件: 2, 4, 6, 13, 17, 90, 140, 164, 201
36CD34+ bone marrow stem cells intravitreal----1件: 90
37Cholesterol1件: Cholesterol1件: D00040 --6件: 19, 90, 160, 259, 261, 310
38Ciliary neurotrophic factor1件: Ciliary neurotrophic factor---1件: 90
39Ciliary Neurotrophic Factor Implant NT-5011件: Ciliary neurotrophic factor---1件: 90
40Circadin1件: Melatonin1件: D08170 2件: MTNR1A,
MTNR1B 💬
2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬3件: 6, 13, 90
41Circadin 2 mg1件: Melatonin1件: D08170 2件: MTNR1A,
MTNR1B 💬
2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬1件: 90
42CIRCADIN 2 mg comprimidos de liberación prolongada1件: Melatonin1件: D08170 2件: MTNR1A,
MTNR1B 💬
2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬1件: 90
43CNS10-NPC implantation----1件: 90
44CNTO 2476----1件: 90
45Combination Product: PRP combined Magnovision----1件: 90
46Compound thrombosis capsule sig: 1.5g/tid1件: Ginkgo biloba---1件: 90
47Conditioned Medium (CM)----1件: 90
48Continuous oxygen1件: Ginkgo biloba---1件: 90
49COQUN----1件: 90
50Cornstarch1件: Starch, corn1件: D05297 --2件: 90, 257
51Cornstarch control1件: Lutein---1件: 90
52Cotoretigene Toliparvovec1件: Timrepigene emparvovec---1件: 90
53CPK850----1件: 90
54Cyclosporine1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
55Cysteine1件: Cysteine2件: D00026 ,
D02326
--11件: 6, 13, 19, 34, 84, 85, 88, 90, 254, 296, 310
56DDS1件: Phosphatidyl serine1件: D04682 --1件: 90
57Dexamethasone1件: Bortezomib1件: D03150 1件: PSMB5 💬8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
58Dexamethasone injection1件: Dexamethasone9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 90
59Diagnostic Test: Ocular Coherence Tomography-Angiography (OCT-A)1件: Sildenafil2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 90, 301
60Docosahexaenoic acid1件: Doconexent---7件: 6, 49, 90, 94, 240, 299, 301
61Dorzolamide1件: Dorzolamide2件: D00653 ,
D07871
13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬
7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬1件: 90
62Eylea1件: Aflibercept1件: D09574 3件: PGF,
VEGFA,
VEGFB 💬
24件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬2件: 90, 166
63Fluocinolone1件: Fluocinolone acetonide1件: D01825 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 90
64Fluocinolone Acetonide1件: Fluocinolone acetonide1件: D01825 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 90
65Gene Therapy Product-vMCO-010----1件: 90
66Gene Therapy product:vMCO-I----1件: 90
67Genetic: AAV5-RPGR----1件: 90
68Genetic: AAV5-RPGR 2e11----1件: 90
69Genetic: AAV5-RPGR 4e11----1件: 90
70Ginkgo1件: Ginkgo biloba---5件: 6, 13, 18, 47, 90
71Ginkgo biloba1件: Ginkgo biloba---4件: 13, 18, 47, 90
72Ginkgo biloba pills sig: 300mg/tid1件: Ginkgo biloba---1件: 90
73GS030-DP----1件: 90
74HORA-PDE6B (AAV2/5.hPDE6B)----1件: 90
75HRPC----1件: 90
76HRPC DP----1件: 90
77Human Embryonic Stem Cell Derived Retinal Pigment Epithelium (RPE)----1件: 90
78Human primary Retinal Pigment Epithelial (HuRPE) cells----1件: 90
79Human retinal progenitor cells----1件: 90
80Human Retinal Progenitor Cells Drug Product----1件: 90
81Hydroxychloroquine1件: Prednisone1件: D00473 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
82Hydroxychloroquine higher dose1件: Hydroxychloroquine1件: D08050 --1件: 90
83Hydroxychloroquine lower dose1件: Hydroxychloroquine1件: D08050 --1件: 90
84Hyperbaric oxygen therapy1件: Oxygen1件: D00003 --1件: 90
85Iluvien1件: Fluocinolone acetonide1件: D01825 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 90
86Injection of stem cells in sub-tenon space of eye for the management of retinitis pigmentosa----1件: 90
87Injection of stem cells in suprachoroidal space of eye for the management of Retinitis Pigmentosa----1件: 90
88Intravitreal autologous CD34+ cells----1件: 90
89Intravitreal injection of Autologous bone marrow Stem Cell----1件: 90
90Intravitreal injection of autologous bone marrow stem cells----1件: 90
91KIO-301----1件: 90
92Lentiviral vector containing MYO7A gene----2件: 90, 303
93Lentiviral vector containing the human MY07A gene----2件: 90, 303
94Levodopa1件: Carbidopa1件: D00558 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬8件: 2, 4, 6, 17, 90, 140, 164, 201
95Levodopa-Carbidopa1件: Carbidopa1件: D00558 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬2件: 6, 90
96Lutein1件: Lutein---3件: 13, 90, 164
97Lutein (10 or 30 mg/day) capsules1件: Lutein---1件: 90
98Lycium Barbarum----1件: 90
99Melatonin1件: Melatonin1件: D08170 2件: MTNR1A,
MTNR1B 💬
2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬12件: 6, 8, 13, 37, 46, 49, 90, 97, 144, 145, 149, 202
100Minocycline1件: Minocycline2件: D00850 ,
D05045
--13件: 2, 6, 8, 13, 46, 85, 90, 94, 162, 201, 206, 280, 299
101N-Acetyl Cysteine (NAC)1件: Cysteine2件: D00026 ,
D02326
--1件: 90
102NAC1件: Acetylcysteine1件: D00221 --5件: 34, 51, 85, 90, 299
103NAC effervescent tablets1件: Acetylcysteine1件: D00221 --1件: 90
104Nerve Growt Factor - 2.5S----1件: 90
105Nerve Growth Factor1件: Nerve Growth Factor---3件: 3, 53, 90
106Nilvadipine1件: Nilvadipine1件: D01908 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 90
107NPI-001----2件: 90, 303
108NT-501----2件: 90, 303
109Null1件: Epoprostenol2件: D00106 ,
D01337
1件: PTGIR 💬3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬16件: 6, 13, 15, 28, 37, 46, 49, 51, 63, 86, 90, 96, 97, 107, 145, 271
110Nutritional Supplement1件: Vitamin A2件: D00069 ,
D06543
2件: RARA,
RARB 💬
8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬1件: 90
111OCU400 High Dose----1件: 90
112OCU400 Low Dose----1件: 90
113OCU400 Mid Dose----1件: 90
114Other: Mock injection----1件: 90
115Other: Observational----1件: 90
116Other: Sham (no implant)1件: Brimonidine2件: D02076 ,
D07540
3件: ADRA2A,
ADRA2B,
ADRA2C 💬
2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 90
117Other: Sham procedure----1件: 90
118Other: Sham-procedure----2件: 90, 303
119Other: Sham-procedure (dose cohort 1&2 only)----2件: 90, 303
120Other: Standard of Care Sildenafil1件: Sildenafil2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 90, 301
121Other: Subconjunctival injection of saline----1件: 90
122Other: Sugar pill----1件: 90
123Other: Visual Acuity (VA)1件: Sildenafil2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 90, 301
124Oxygen1件: Oxygen1件: D00003 --20件: 6, 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 168, 193, 226, 271, 294, 299, 330
125Phosphate1件: Riboflavin3件: D00050 ,
D01622 ,
D01913
--33件: 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
126Platelet Rich Plasma----2件: 46, 90
127Prescribe N-acetylcysteine tablets1件: Acetylcysteine1件: D00221 --1件: 90
128PRP----1件: 90
129PS1件: Phosphatidyl serine1件: D04682 --4件: 6, 46, 90, 97
130QLT091001----1件: 90
131QR-1123----1件: 90
132QR-421a----2件: 90, 303
133RAAV.hPDE6A vector----1件: 90
134RAAV2tYF-GRK1-hRPGRco----1件: 90
135RAAV2tYF-GRK1-RPGR----1件: 90
136Recombinant adeno-associated viral vector serotype 2.7m8 containing the ChrimsonR-tdTomato gene----1件: 90
137RECOMBINANT HUMAN NERVE GROWTH FACTOR (RHNGF)1件: Nerve Growth Factor---1件: 90
138Retinal pigment epitheliums transplantation----1件: 90
139RhNGF1件: Cenegermin1件: D11028 1件: NGFR 💬8件: Apoptosis - multiple species, Cytokine-cytokine receptor interaction, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer 💬2件: 53, 90
140RhNGF 180 µg/ml eye drops solution1件: Cenegermin1件: D11028 1件: NGFR 💬8件: Apoptosis - multiple species, Cytokine-cytokine receptor interaction, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer 💬1件: 90
141RhNGF 60 µg/ml eye drops solution1件: Cenegermin1件: D11028 1件: NGFR 💬8件: Apoptosis - multiple species, Cytokine-cytokine receptor interaction, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer 💬1件: 90
142RNA antisense oligonucleotide for intravitreal injection----2件: 90, 303
143RST-001----1件: 90
144SAR421869----2件: 90, 303
145Sham1件: Poractant alfa1件: D08402 --3件: 90, 211, 303
146Sham Injection----1件: 90
147Sildenafil1件: Sildenafil2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
148Sodium Valproate1件: Valproic acid1件: D00399 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬
17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬4件: 2, 90, 102, 256
149Stem Cell Transplantation1件: Alemtuzumab1件: D02802 --13件: 13, 19, 20, 46, 51, 60, 62, 65, 90, 125, 164, 234, 326
150Stem/progenitor cells transplantation----2件: 90, 301
151Subretinal administration of rAAV2-VMD2-hMERTKRecombinant Adeno-Associated Virus----1件: 90
152Subretinal injection of rAAV.hPDE6A----1件: 90
153Subretinal injection of umbilical cord blood platelet-rich plasma (CB-PRP)----1件: 90
154Timrepigene emparvovec1件: Timrepigene emparvovec---1件: 90
155Tocoferol1件: Nilvadipine1件: D01908 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 90
156Triamcinolone1件: Triamcinolone5件: D00385 ,
D00983 ,
D00984 ,
D00985 ,
D06216
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
157Twice-daily dosage with 0.5% cyclosporine-A eyedrops1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬1件: 90
158UF-021----1件: 90
159UF-021 (isopropyl unoprostone)1件: Unoprostone1件: D08661 1件: PTGFR 💬3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬1件: 90
160UF-021(isopropyl unoprostone)1件: Unoprostone1件: D08661 1件: PTGFR 💬3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬1件: 90
161Umbilical Cord Mesenchymal Stem Cell (UC-MSC)----1件: 90
162Unoprostone1件: Unoprostone1件: D08661 1件: PTGFR 💬3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬1件: 90
163UshStat----2件: 90, 303
164UshStat (SAR421869)----2件: 90, 303
165VA1件: Sildenafil2件: D02229 ,
D08514
1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬3件: 90, 301, 302
166Valproate1件: Valproic acid1件: D00399 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬
17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬6件: 2, 3, 90, 102, 233, 256
167Valproic Acid1件: Cetuximab1件: D03455 1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬10件: 3, 5, 26, 34, 65, 89, 90, 222, 256, 331
168Vehicle eye drops1件: Cenegermin1件: D11028 1件: NGFR 💬8件: Apoptosis - multiple species, Cytokine-cytokine receptor interaction, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer 💬1件: 90
169Vitamin A1件: Vitamin A2件: D00069 ,
D06543
2件: RARA,
RARB 💬
8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬3件: 13, 53, 90
170Vitamin AD sig: 1 tablet/tid1件: Ginkgo biloba---1件: 90
171Vitamin B sig: 10mg/tid1件: Ginkgo biloba---1件: 90
172Vitamin E1件: Vitamin E1件: D02331 --11件: 2, 6, 13, 20, 46, 90, 96, 97, 206, 299, 317
173Wharton's jelly derived mesenchymal stem cell----1件: 90
174Zuretinol Acetate1件: Zuretinol acetate---1件: 90