KEGG DRUG

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No.

薬物名（臨床試験情報から抽出）

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

指定難病告示番号

Abatacept (ABA) + Methotrexate (MTX), double-blind (DB)
(D00142)

2件: Abatacept,
Methotrexate

2件: Methotrexate (D00142),
Abatacept 💬

Name	Other Names
Methotrexate	Methotrexate (JP18/USP/INN) Otrexup (TN) Xatmep (TN) REDITREX メトトレキサートメソトレキセートメトジェクトリウマトレックス
Abatacept	Abatacept (USAN/INN) Abatacept (genetical recombination) (JAN) Orencia (TN) アバタセプトオレンシア

4件: CD80,
CD86,
DHFR,
DHFR2 💬

18件: Allograft rejection, Antifolate resistance, Autoimmune thyroid disease, Biosynthesis of cofacto ...

1件: 46 💬

Abatacept + Methotrexate
(D00142)

2件: Abatacept,
Methotrexate

2件: Methotrexate (D00142),
Abatacept 💬

Name	Other Names
Methotrexate	Methotrexate (JP18/USP/INN) Otrexup (TN) Xatmep (TN) REDITREX メトトレキサートメソトレキセートメトジェクトリウマトレックス
Abatacept	Abatacept (USAN/INN) Abatacept (genetical recombination) (JAN) Orencia (TN) アバタセプトオレンシア

4件: CD80,
CD86,
DHFR,
DHFR2 💬

18件: Allograft rejection, Antifolate resistance, Autoimmune thyroid disease, Biosynthesis of cofacto ...

1件: 46 💬

Adalimumab with methotrexate
(D00142)

2件: Adalimumab,
Methotrexate

2件: Methotrexate (D00142),
Adalimumab 💬

Name

Other Names

Methotrexate

Methotrexate (JP18/USP/INN)
Otrexup (TN)
Xatmep (TN)
REDITREX
メトトレキサート
メソトレキセート
メトジェクト
リウマトレックス

Adalimumab

Adalimumab (USAN/INN)
Adalimumab (genetical recombination) (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 1] (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 2] (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 3] (JAN)
Adalimumab-adaz
Adalimumab-adbm
Adalimumab-afzb
Adalimumab-atto
Adalimumab-bwwd
Adalimumab-fkjp
Humira (TN)
Abrilada (TN)
Amjevita (TN)
Cyltezo (TN)
Hadlima (TN)
Hyrimoz (TN)
アダリムマブ
ヒュミラ
アダリムマブBS

3件: DHFR,
DHFR2,
TNF 💬

71件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

1件: 46 💬

AZATHIOPRINE or METHOTREXATE
(D00142)

2件: Azathioprine,
Methotrexate

2件: Methotrexate (D00142),
Azathioprine 💬

Name	Other Names
Methotrexate	Methotrexate (JP18/USP/INN) Otrexup (TN) Xatmep (TN) REDITREX メトトレキサートメソトレキセートメトジェクトリウマトレックス
Azathioprine	Azathioprine (JP18/USP/INN) Azasan (TN) Imuran (TN) Jayempi (TN) アザチオプリンアザニンイムラン

2件: DHFR,
DHFR2 💬

5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One c ...

1件: 96 💬

BMS-582949 and Methotrexate
(D00142)

2件: BMS-582949,
Methotrexate

1件: Methotrexate (D00142) 💬

2件: DHFR,
DHFR2 💬

5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One c ...

1件: 46 💬

Busulfan/Fludarabine phosphate/Tacrolimus/Methotrexate/G-CSF
(D00142)

6件: Busulfan,
Filgrastim,
Fludarabine,
Methotrexate,
Phosphate ion,
Tacrolimus

6件: Tacrolimus ,
Methotrexate (D00142),
Busulfan ,
Filgrastim ,
Fludarabine ,
Tacrolimus ...

Name	Other Names
Tacrolimus	Tacrolimus (USP/INN) Tacrolimus hydrate (JP18) Prograf (TN) Protopic (TN) ASTAGRAF XL ENVARSUS タクロリムス水和物グラセプタータリムスプログラフプロトピックタクロリムス
Methotrexate	Methotrexate (JP18/USP/INN) Otrexup (TN) Xatmep (TN) REDITREX メトトレキサートメソトレキセートメトジェクトリウマトレックス
Busulfan	Busulfan (JP18/USP/INN) Myleran (TN) BUSULFEX ブスルファンブスルフェクスマブリン
Filgrastim	Filgrastim (USP/INN) Filgrastim (genetical recombination) (JP18) Filgrastim (genetical recombination) [Filgrastim biosimilar 1] (JAN) Tbo-filgrastim Filgrastim (genetical recombination) [Filgrastim biosimilar 2] (JAN) Filgrastim (genetical recombination) [Filgrastim biosimilar 3] (JAN) Filgrastim-sndz Filgrastim-aafi Neupogen (TN) Nivestym (TN) Grastofil (TN) Zarxio (TN) GRANIX RELEUKO フィルグラスチムグランフィルグラスチムBS
Fludarabine	Fludarabine (INN) Fluradosa (TN) フルダラビン
Tacrolimus	Tacrolimus (INN) Prograf (TN) タクロリムス

9件: CSF3R,
DHFR,
DHFR2,
PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2,
RRM1 💬

Name	Full Name
CSF3R	colony stimulating factor 3 receptor
DHFR	dihydrofolate reductase
DHFR2	dihydrofolate reductase 2
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta
RRM1	ribonucleotide reductase catalytic subunit M1

48件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Antifolate resistance, ...

1件: 60 💬

Certolizumab Pegol + Methotrexate (MTX)
(D00142)

2件: Certolizumab pegol,
Methotrexate

2件: Methotrexate (D00142),
Certolizumab pegol 💬

Name	Other Names
Methotrexate	Methotrexate (JP18/USP/INN) Otrexup (TN) Xatmep (TN) REDITREX メトトレキサートメソトレキセートメトジェクトリウマトレックス
Certolizumab pegol	Certolizumab pegol (USAN/INN) Certolizumab pegol (genetical recombination) (JAN) Cimzia (TN) セルトリズマブペゴルシムジア

3件: DHFR,
DHFR2,
TNF 💬

71件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

1件: 46 💬

Clobetasol propionate + Methotrexate
(D00142)

3件: Clobetasol,
Clobetasol propionate,
Methotrexate

3件: Methotrexate (D00142),
Clobetasol propionate ,
Clobetasol 💬

Name	Other Names
Methotrexate	Methotrexate (JP18/USP/INN) Otrexup (TN) Xatmep (TN) REDITREX メトトレキサートメソトレキセートメトジェクトリウマトレックス
Clobetasol propionate	Clobetasol propionate (JP18/USP) Clobex (TN) Cormax (TN) Olux (TN) IMPEKLO OLUX-E CLOBETASOL PROPIONATE CREAM USP, 0.05% CLODAN クロベタゾールプロピオン酸エステルプロピオン酸クロベタゾールコムクロデルモベートグリジール
Clobetasol	Clobetasol (INN) Clobecort Amex (TN) クロベタゾール

3件: DHFR,
DHFR2,
NR3C1 💬

6件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Neuro ...

1件: 162 💬

Combination Product: Exercise, and methotrexate
(D00142)

1件: Methotrexate

1件: Methotrexate (D00142) 💬

2件: DHFR,
DHFR2 💬

5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One c ...

1件: 46 💬

Combination Product: Laser, exercise, and methotrexate
(D00142)

1件: Methotrexate

1件: Methotrexate (D00142) 💬

2件: DHFR,
DHFR2 💬

5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One c ...

1件: 46 💬

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