Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acamprosate 1件: Acamprosate1件: Acamprosate 💬 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬2件: 6, 206 💬
2 Acetate 1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
3 alpha-Tocopherol acetate 3件: Tocopherol acetate; TOCOPHERYL ACETATE; Vitamin E---2件: 49, 206 💬
4 Arbaclofen 2件: Arbaclofen; BACLOFEN1件: Arbaclofen 💬 2件: GABBR1,
GABBR2 💬 		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬2件: 13, 206 💬
5 Aripiprazole 1件: Aripiprazole1件: Aripiprazole 💬 4件: DRD2,
DRD3,
HTR1A,
HTR2A 💬 		12件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 206 💬
6 Ascorbic acid 4件: Acidum ascorbicum; Ascorbic Acid; Iron; Vitamin C1件: Ascorbic acid 💬 --8件: 10, 97, 192, 206, 210, 211, 212, 298 💬
7 AZD-7325 0件: ---1件: 206 💬
8 Baclofen 2件: Baclofen; Kemstro1件: Baclofen 💬 2件: GABBR1,
GABBR2 💬 		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬8件: 2, 10, 13, 18, 65, 70, 149, 206 💬
9 Cannabidiol 4件: CANNABIDIOL; Epidiolex; Epidyolex; Sativex1件: Cannabidiol 💬 2件: CNR1,
CNR2 💬 		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
10 CX516 1件: CX516---1件: 206 💬
11 Donepezil 3件: ARICEPT; Donepezil; Donepezil hydrochloride1件: Donepezil 💬 1件: ACHE 💬 2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
12 Epigallocatechin gallate 3件: EGCG; Epigallocatechin gallate; Epigallocatechin-3-gallate---9件: 6, 8, 13, 17, 28, 85, 113, 206, 299 💬
13 Ergoloid mesylate 2件: Dihydroergotoxine Mesylate; Ergoloid Mesylate---2件: 6, 206 💬
14 Flumazenil 1件: Flumazenil1件: Flumazenil 💬 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 13, 17, 18, 206 💬
15 Fluoxetine 5件: Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC1件: Fluoxetine 💬 1件: SLC6A4 💬 2件: Serotonergic synapse, Synaptic vesicle cycle 💬6件: 13, 17, 78, 86, 179, 206 💬
16 Gaboxadol 1件: Gaboxadol1件: Gaboxadol 💬 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 201, 206 💬
17 Ganaxolone 1件: Ganaxolone1件: Ganaxolone 💬 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬4件: 145, 152, 158, 206 💬
18 Lovastatin 1件: Lovastatin1件: Lovastatin 💬 1件: HMGCR 💬 4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
19 Manganese citrate 1件: Release---12件: 6, 8, 13, 46, 65, 78, 81, 96, 97, 206, 226, 299 💬
20 Mavoglurant 1件: Mavoglurant---2件: 6, 206 💬
21 Memantine 3件: Ebixa; MEMANTINE; MEMANTINE HYDROCHLORIDE1件: Memantine 💬 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
22 Metformin 5件: Metformin; Metformin HCl; METFORMIN HYDROCHLORIDE; Metformina; Metformine1件: Metformin 💬 2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
23 Methylphenidate 3件: Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin1件: Methylphenidate 💬 2件: SLC6A2,
SLC6A3 💬 		7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬7件: 6, 13, 34, 84, 113, 179, 206 💬
24 Minocycline 3件: Minocycline; MINOCYCLINE HYDROCHLORIDE; Minomycin1件: Minocycline 💬 --14件: 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299 💬
25 Oxytocin 2件: Oxytocin; Syntocinon1件: Oxytocin 💬 1件: OXTR 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬7件: 6, 72, 127, 168, 193, 206, 226 💬
26 Pyridoxine 2件: PYRIDOXINE; Vitamin B61件: Pyridoxine 💬 --5件: 6, 93, 145, 206, 320 💬
27 Riluzole 2件: Rilutek; Riluzole1件: Riluzole 💬 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
28 Risperidone 1件: Risperidone1件: Risperidone 💬 2件: DRD2,
HTR2A 💬 		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬5件: 8, 156, 179, 187, 206 💬
29 Roflumilast 1件: Roflumilast1件: Roflumilast 💬 4件: PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		5件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬4件: 84, 97, 206, 299 💬
30 Sertraline 1件: Sertraline1件: Sertraline 💬 1件: SLC6A4 💬 2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 206 💬
31 STX-107 0件: ---1件: 206 💬
32 Sulindac 1件: Sulindac1件: Sulindac 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 206 💬
33 Tocopherol 2件: Tocoferol; TOCOPHEROL1件: Tocopherol 💬 --6件: 13, 49, 90, 206, 257, 298 💬
34 Vitamin E 2件: Alpha-tocopherol; Vitamin E1件: Vitamin E 💬 --12件: 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬
35 Water 8件: AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION1件: Water 💬 --21件: 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
36 Zatolmilast 1件: Zatolmilast1件: Zatolmilast 💬 1件: PDE4D 💬 5件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬1件: 206 💬