Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abatacept 2件: Abatacept; ORENCIA1件: Abatacept 💬2件: CD80,
CD86 💬
13件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Acetaminophen 4件: Acetaminophen; PARACETAMOL; Tylenol; Ultracet1件: Acetaminophen 💬2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
3 Acetate 1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
4 Adalimumab 7件: Adalimumab; AMGEVITA; Cyltezo; Hulio; HUMIRA; Hyrimoz; Imraldi1件: Adalimumab 💬1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
5 Aldosterone 1件: Aldosterone1件: Aldosterone 💬1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬1件: 222 💬
6 Aliskiren 1件: Aliskiren1件: Aliskiren 💬1件: REN 💬3件: Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬3件: 66, 167, 222 💬
7 Amoxicillin 4件: Amoxicilina; Amoxicillin; Amoxycillin; Augmentin2件: Amoxicillin ,
Amoxicillin 💬
--9件: 6, 19, 46, 63, 84, 96, 97, 222, 299 💬
8 Angiotensin II 2件: Angiotensin; Angiotensin II2件: Angiotensin II ,
Angiotensin II 💬
2件: AGTR1,
AGTR2 💬
16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 17, 19, 46, 66, 86, 222, 224 💬
9 Apixaban 2件: Apixaban; Eliquis1件: Apixaban 💬1件: F10 💬1件: Complement and coagulation cascades 💬1件: 222 💬
10 Atorvastatin 3件: Atorvastatin; Atorvastatin calcium; Lipitor1件: Atorvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
11 Atrasentan 1件: ATRASENTAN---3件: 66, 218, 222 💬
12 Avacopan 1件: AVACOPAN1件: Avacopan 💬1件: C5AR1 💬6件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬3件: 43, 44, 222 💬
13 Bardoxolone 1件: Bardoxolone1件: Bardoxolone 💬--7件: 66, 67, 84, 85, 86, 218, 222 💬
14 Bardoxolone methyl 1件: Bardoxolone Methyl1件: Bardoxolone methyl 💬--7件: 66, 67, 84, 85, 86, 218, 222 💬
15 Basiliximab 2件: Basiliximab; Simulect1件: Basiliximab 💬1件: IL2RA 💬11件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬6件: 2, 50, 66, 97, 222, 228 💬
16 Belimumab 2件: Belimumab; Benlysta1件: Belimumab 💬1件: TNFSF13B 💬4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬
17 Bleselumab 1件: Bleselumab1件: Bleselumab 💬1件: CD40 💬17件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬1件: 222 💬
18 Bortezomib 3件: Bortezomib; Bortezomib Accord; Velcade1件: Bortezomib 💬1件: PSMB5 💬8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
19 Butyric Acid 4件: Butanoic acid; Butyrate; Butyric Acid; Sodium Butyrate---7件: 34, 46, 51, 97, 156, 222, 291 💬
20 Calcium 2件: Calcio; Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
21 CCX-140 0件: ---1件: 222 💬
22 Cefadroxil 0件: 2件: Cefadroxil ,
Cefadroxil 💬
--2件: 222, 240 💬
23 Chlorambucil 1件: Chlorambucil1件: Chlorambucil 💬--1件: 222 💬
24 Cholesterol 1件: Cholesterol1件: Cholesterol 💬--6件: 8, 19, 90, 160, 222, 310 💬
25 Clarithromycin 1件: Clarithromycin1件: Clarithromycin 💬--8件: 6, 63, 84, 96, 97, 222, 228, 299 💬
26 Corticotropin 5件: ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin1件: Corticotropin 💬1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬12件: 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
27 Creatinine 1件: Creatinine1件: Creatinine 💬--5件: 2, 46, 60, 70, 222 💬
28 CXA-10 1件: CXA-10---2件: 86, 222 💬
29 Cyclophosphamide 6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; CYCLOPHOSPHAMIDE; Cyclophosphamidum; Cytoxan2件: Cyclophosphamide ,
Cyclophosphamide 💬
--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
30 Cyclosporine 10件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS1件: Cyclosporine 💬5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
31 Dalteparin 2件: Dalteparin; Fragmin---1件: 222 💬
32 Dapagliflozin 2件: Dapagliflozin; Forxiga1件: Dapagliflozin 💬1件: SLC5A2 💬-7件: 19, 49, 66, 67, 86, 88, 222 💬
33 Dexamethasone 5件: Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex1件: Dexamethasone 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
34 Diphenhydramine 2件: Diphenhydramine; Diphenhydramine hydrochloride1件: Diphenhydramine 💬1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬8件: 11, 13, 49, 51, 70, 86, 222, 256 💬
35 Eculizumab 2件: ECULIZUMAB; SOLIRIS1件: Eculizumab 💬1件: C5 💬11件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬7件: 11, 13, 14, 61, 62, 109, 222 💬
36 Enalapril 2件: ENALAPRIL; Enalapril Maleate1件: Enalapril 💬1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬6件: 19, 46, 66, 113, 210, 222 💬
37 Evolocumab 2件: Evolocumab; Repatha1件: Evolocumab 💬1件: PCSK9 💬1件: Cholesterol metabolism 💬2件: 79, 222 💬
38 Felzartamab 1件: Felzartamab---2件: 66, 222 💬
39 Filgotinib 2件: FILGOTINIB; Jyseleca1件: Filgotinib 💬1件: JAK1 💬27件: Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬6件: 46, 53, 96, 97, 222, 271 💬
40 Fluvastatin 1件: Fluvastatin1件: Fluvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 79, 218, 222 💬
41 Fosfomycin 1件: Fosfomycin1件: Fosfomycin 💬--3件: 96, 97, 222 💬
42 Fresolimumab 2件: Fresolimumab; GC10081件: Fresolimumab 💬3件: TGFB1,
TGFB2,
TGFB3 💬
35件: AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Diabetic cardiomyopathy, Dilated cardiomyopathy, FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy, Inflammatory bowel disease, Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬3件: 51, 85, 222 💬
43 Galactose 2件: D-Galactose; Galactose1件: Galactose 💬--1件: 222 💬
44 Gold 1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬
45 Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen 2件: ACT-HIB; ActHIB---5件: 14, 61, 62, 66, 222 💬
46 Hydroxychloroquine 3件: Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE; PLAQUENIL1件: Hydroxychloroquine 💬--27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
47 Interleukin-1 alpha, human recombinant 1件: None---18件: 6, 46, 51, 65, 66, 84, 85, 96, 97, 140, 161, 171, 222, 231, 246, 271, 299, 337 💬
48 Iohexol 2件: Iohexol; OMNIPAQUE1件: Iohexol 💬--3件: 19, 67, 222 💬
49 Iptacopan 1件: Iptacopan1件: Iptacopan 💬1件: CFB 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬5件: 61, 62, 66, 109, 222 💬
50 Irbesartan 2件: Aprovel; IRBESARTAN1件: Irbesartan 💬1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬4件: 66, 167, 168, 222 💬
51 L-Glutamine 2件: Glutamine; L-Glutamine1件: Glutamine 💬--8件: 87, 89, 96, 97, 113, 222, 245, 299 💬
52 Lanraplenib 1件: Lanraplenib1件: Lanraplenib 💬--2件: 53, 222 💬
53 Lansoprazole 1件: Lansoprazole1件: Lansoprazole 💬2件: ATP4A,
ATP4B 💬
4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299 💬
54 Levamisole 1件: Levamisole1件: Levamisole 💬--4件: 60, 61, 62, 222 💬
55 Levothyroxine 2件: Levothyroxine; Thyroxine1件: Levothyroxine 💬2件: THRA,
THRB 💬
2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬5件: 19, 49, 78, 80, 222 💬
56 Lisinopril 2件: LISINOPRIL; ZESTRIL2件: Lisinopril ,
Lisinopril 💬
1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 19, 46, 49, 66, 67, 113, 222 💬
57 Losartan 3件: Cozaar; Losartan; LOSARTAN POTASSIUM1件: Losartan 💬1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
58 Losmapimod 1件: Losmapimod1件: Losmapimod 💬4件: MAPK11,
MAPK12,
MAPK13,
MAPK14 💬
62件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬2件: 113, 222 💬
59 Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine 1件: Menveo---6件: 11, 13, 61, 62, 66, 222 💬
60 Meningococcal polysaccharide vaccine group A 2件: Menveo; Nimenrix1件: Meningococcal polysaccharide vaccine group A 💬--7件: 11, 13, 50, 61, 62, 66, 222 💬
61 Meningococcal polysaccharide vaccine group C 2件: Menveo; Nimenrix1件: Meningococcal polysaccharide vaccine group C 💬--7件: 11, 13, 50, 61, 62, 66, 222 💬
62 Meningococcal polysaccharide vaccine group W-135 2件: MENVEO; Nimenrix---7件: 11, 13, 50, 61, 62, 66, 222 💬
63 Meningococcal polysaccharide vaccine group Y 2件: Menveo; Nimenrix---7件: 11, 13, 50, 61, 62, 66, 222 💬
64 Methylprednisolone 4件: Medrol; Methylprednisolon; METHYLPREDNISOLONE; METHYLPREDNISOLONE ACETATE1件: Methylprednisolone 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
65 Methylprednisone 1件: Methylprednisone---4件: 46, 66, 85, 222 💬
66 Mizoribine 2件: BREDININ; Mizoribine1件: Mizoribine 💬2件: IMPDH1,
IMPDH2 💬
4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
67 Monomethyl fumarate 2件: Bafiertam; Monomethyl fumarate1件: Monomethyl fumarate 💬--16件: 13, 35, 40, 46, 49, 50, 51, 60, 65, 66, 107, 162, 222, 224, 226, 299 💬
68 Mycophenolate mofetil 3件: CellCept; Mycophenolate mofetil; Mycophenolate mofetil TEVA1件: Mycophenolate mofetil 💬2件: IMPDH1,
IMPDH2 💬
4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
69 Mycophenolic acid 5件: Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic1件: Mycophenolic acid 💬2件: IMPDH1,
IMPDH2 💬
4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
70 Narsoplimab 2件: MASP-2 antibody; Narsoplimab1件: Narsoplimab 💬1件: MASP2 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬4件: 64, 66, 109, 222 💬
71 Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen 1件: Menveo---6件: 11, 13, 61, 62, 66, 222 💬
72 Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen 1件: Menveo---6件: 11, 13, 61, 62, 66, 222 💬
73 Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen 1件: Menveo---6件: 11, 13, 61, 62, 66, 222 💬
74 Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen 1件: Menveo---6件: 11, 13, 61, 62, 66, 222 💬
75 Neisseria meningitidis serogroup b fhbp fusion protein antigen 1件: Bexsero---6件: 11, 13, 61, 62, 66, 222 💬
76 Neisseria meningitidis serogroup b nada protein antigen 1件: Bexsero---6件: 11, 13, 61, 62, 66, 222 💬
77 Neisseria meningitidis serogroup b nhba fusion protein antigen 1件: Bexsero---6件: 11, 13, 61, 62, 66, 222 💬
78 Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle 1件: Bexsero---6件: 11, 13, 61, 62, 66, 222 💬
79 Nitric Oxide 3件: INOmax; NITRIC OXIDE; Nitrosyl1件: Nitric oxide 💬--12件: 6, 58, 85, 86, 88, 97, 210, 222, 251, 294, 299, 321 💬
80 Obinutuzumab 2件: Gazyvaro; Obinutuzumab1件: Obinutuzumab 💬1件: MS4A1 💬1件: Hematopoietic cell lineage 💬4件: 43, 44, 49, 222 💬
81 Panax notoginseng root 1件: Sanqi1件: Panax notoginseng root 💬--1件: 222 💬
82 Pegcetacoplan 2件: Aspaveli; PEGCETACOPLAN1件: Pegcetacoplan 💬1件: C3 💬17件: Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬4件: 2, 61, 62, 222 💬
83 Pentoxifylline 1件: Pentoxifylline1件: Pentoxifylline 💬--12件: 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298 💬
84 Perindopril 2件: Coversyl; Perindopril1件: Perindopril 💬1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 58, 113, 167, 222 💬
85 Pirfenidone 2件: Esbriet; Pirfenidone1件: Pirfenidone 💬6件: CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬
84件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
86 Prednisolone 3件: Prednisolona; Prednisolone; Prednisolonum1件: Prednisolone 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
87 Prednisolone acetate 1件: PREDNISOLONE ACETATE1件: Prednisolone acetate 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 222 💬
88 Prednisone 3件: Prednisona; Prednisone; RAYOS1件: Prednisone 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
89 Resiniferatoxin 0件: ---5件: 11, 46, 65, 222, 240 💬
90 Rituximab 6件: MABTHERA; Rituxan; RITUXIMAB; Rixathon; Ruxience; TRUXIMA1件: Rituximab 💬1件: MS4A1 💬1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
91 Rosiglitazone 2件: Rosiglitazone; Rosiglitazone maleate1件: Rosiglitazone 💬1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬5件: 46, 75, 97, 222, 265 💬
92 Sacubitril 2件: Entresto; Sacubitril1件: Sacubitril 💬1件: MME 💬4件: Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬2件: 58, 222 💬
93 Sinomenine 1件: Sinomenine---2件: 46, 222 💬
94 Sirolimus 3件: RAPAMUNE; Rapamycin; Sirolimus1件: Sirolimus 💬1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
95 Sparsentan 1件: SPARSENTAN1件: Sparsentan 💬2件: AGTR1,
EDNRA 💬
17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 66, 218, 222 💬
96 Streptococcus pneumoniae type 1 capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
97 Streptococcus pneumoniae type 14 capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
98 Streptococcus pneumoniae type 18c capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
99 Streptococcus pneumoniae type 19a capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
100 Streptococcus pneumoniae type 19f capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
101 Streptococcus pneumoniae type 23f capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
102 Streptococcus pneumoniae type 3 capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
103 Streptococcus pneumoniae type 4 capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
104 Streptococcus pneumoniae type 5 capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
105 Streptococcus pneumoniae type 6b capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
106 Streptococcus pneumoniae type 7f capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
107 Streptococcus pneumoniae type 9v capsular polysaccharide antigen 2件: Pneumovax 23; Prevenar 13---6件: 13, 14, 46, 50, 96, 222 💬
108 Sulfate ion 1件: Sulfate---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299 💬
109 Tacrolimus 2件: Prograf; Tacrolimus2件: Tacrolimus ,
Tacrolimus 💬
5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
110 Tetracosactide 4件: Cosyntropin; Synacthen Depot; Tetracosactide; Tetracosactrin1件: Cosyntropin 💬1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 78, 83, 113, 145, 222 💬
111 Tripterygium wilfordii whole 2件: Tripterygium; Tripterygium Wilfordii---8件: 46, 66, 67, 96, 162, 222, 224, 271 💬
112 TRU-015 1件: TRU-015---3件: 46, 49, 222 💬
113 Valproic acid 3件: Valproate; VALPROATE SODIUM; Valproic Acid1件: Valproic acid 💬7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬
17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬14件: 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
114 Valsartan 3件: Diovan; Entresto; Valsartan1件: Valsartan 💬1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 57, 58, 66, 75, 218, 222, 224 💬
115 Vitamin D 3件: Calciferol; Cod liver oil; Vitamin D---20件: 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299 💬
116 Voclosporin 1件: Voclosporin1件: Voclosporin 💬5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬2件: 49, 222 💬
117 Zanubrutinib 1件: Zanubrutinib1件: Zanubrutinib 💬1件: BTK 💬7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬5件: 13, 63, 222, 300, 331 💬