Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abacavir 4件: Abacavir; Abacavir sulfate; Triumeq; Ziagen2件: D00891 ,
D07057
--4件: 2, 135, 265, 325
2 Acetate 1件: Acetate---43件: 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
3 Acetylcarnitine 2件: Acetyl-L-carnitine; Acetylcarnitine---3件: 2, 265, 298
4 Acipimox 1件: Acipimox1件: D07190 --2件: 78, 265
5 Amprenavir 1件: Amprenavir1件: D00894 --1件: 265
6 ANX-510 0件: ---3件: 6, 265, 288
7 Aramchol 1件: Aramchol---1件: 265
8 Atazanavir 2件: Atazanavir; Reyataz2件: D01276 ,
D07471
--1件: 265
9 Atorvastatin 3件: Atorvastatin; Atorvastatin Calcium; Lipitor3件: D00258 ,
D00887 ,
D07474
1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
10 Baricitinib 2件: Baricitinib; Olumiant1件: D10308 2件: JAK1,
JAK2 💬
35件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
11 Berberine 1件: Berberine---2件: 97, 265
12 Caffeine 1件: Caffeine2件: D00528 ,
D01453
11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬
22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
13 Calcium 2件: Calcio; Calcium---30件: 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
14 Cholic Acid 1件: Cholic Acid1件: D10699 1件: NR1H4 💬1件: Bile secretion 💬4件: 20, 234, 265, 310
15 Cyclophosphamide 6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan2件: D00287 ,
D07760
--45件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
16 Didanosine 1件: Didanosine1件: D00296 --2件: 25, 265
17 Diosmin 1件: DIOSMIN1件: D07858 --1件: 265
18 Dolutegravir 2件: Dolutegravir; Triumeq1件: D10066 --2件: 2, 265
19 Doravirine 1件: Doravirine1件: D10624 --1件: 265
20 Efavirenz 2件: Efavirenz; SUSTIVA1件: D00896 --1件: 265
21 Emtricitabine 2件: Emtricitabine; TRUVADA1件: D01199 --4件: 25, 93, 265, 325
22 Enfuvirtide 1件: Enfuvirtide1件: D02499 --2件: 25, 265
23 Fenofibrate 1件: Fenofibrate1件: D00565 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬5件: 8, 79, 93, 94, 265
24 Gemcabene 1件: Gemcabene---2件: 79, 265
25 Glycerin 3件: Bee venom; Glycerine; Glycerol1件: D00028 --6件: 6, 13, 79, 265, 316, 317
26 Indinavir 1件: Indinavir3件: D00897 ,
D02861 ,
D03833
--1件: 265
27 L-Lactic acid 2件: L-Lactic acid; Lactic acid---1件: 265
28 Lactic acid 1件: Lactic acid1件: D00111 --2件: 265, 299
29 Lamivudine 4件: COMBIVIR; Epivir; Lamivudine; Triumeq1件: D00353 --7件: 2, 26, 42, 46, 135, 265, 325
30 Leptin 1件: Leptin---2件: 6, 265
31 Levocarnitine 4件: Carnitine; L-Carnitine; Levocarnitine; Xyzal3件: D02030 ,
D02176 ,
D04713
--11件: 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
32 Lopinavir 2件: Kaletra; Lopinavir1件: D01425 --2件: 93, 265
33 Mecasermin 3件: Increlex; Mecasermin; MECASERMINA2件: D03297 ,
D04870
2件: GHR,
IGF1R 💬
33件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬6件: 65, 78, 96, 168, 265, 299
34 Metformin 5件: METFORMIN; Metformin HCl; Metformin Hydrochloride; METFORMINA; Metformine2件: D00944 ,
D04966
2件: PRKAA1,
PRKAA2 💬
20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
35 Metreleptin 3件: METRELEPTIN; Myalept; R-metHuLeptin1件: D05014 1件: LEPR 💬6件: AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬1件: 265
36 Nelfinavir 1件: Nelfinavir2件: D00899 ,
D08259
--3件: 49, 265, 331
37 Nevirapine 1件: Nevirapine1件: D00435 --1件: 265
38 Niacin 2件: Niacin; Nicotinic acid1件: D00049 --4件: 6, 78, 79, 265
39 Obeticholic acid 4件: 6-ECDCA; 6-ethylchenodeoxycholic acid; Obeticholic Acid; Ocaliva1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬3件: 93, 265, 296
40 Pioglitazone 1件: Pioglitazone2件: D00945 ,
D08378
1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
41 Poly(lactic acid) 1件: POLY-L-LACTIC ACID---1件: 265
42 Pravastatin 2件: Pravastatin; Pravastatin sodium2件: D00893 ,
D08410
1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬9件: 13, 46, 49, 67, 79, 96, 164, 265, 333
43 Pyrimethamine 2件: Daraprim; PYRIMETHAMINE1件: D00488 --11件: 2, 4, 6, 13, 19, 46, 51, 65, 96, 97, 265
44 Raltegravir 2件: ISENTRESS; Raltegravir1件: D06676 --4件: 13, 26, 93, 265
45 Riboflavin 2件: Riboflavin; Vitamin B23件: D00050 ,
D01622 ,
D01913
--8件: 13, 38, 46, 96, 97, 162, 168, 265
46 Ritonavir 2件: Norvir; Ritonavir1件: D00427 --3件: 2, 86, 265
47 Rosiglitazone 2件: Rosiglitazone; Rosiglitazone maleate2件: D00596 ,
D08491
1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬5件: 46, 75, 97, 222, 265
48 Saquinavir 1件: Saquinavir2件: D00429 ,
D01160
--2件: 86, 265
49 Setmelanotide 1件: Setmelanotide1件: D11927 1件: MC4R 💬1件: Neuroactive ligand-receptor interaction 💬2件: 202, 265
50 Simvastatin 3件: SIMVASTATIN; Simvastatina; Simvastatine1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
51 Somatotropin 17件: Genotropin; Growth hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; Somatropin; SOMATROPINA; Zomacton1件: D02691 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬23件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
52 Stavudine 1件: Stavudine1件: D00445 --1件: 265
53 Sulfate ion 1件: Sulfate---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 218, 222, 226, 265, 296, 297, 299
54 Tenofovir 1件: Tenofovir1件: D06074 --6件: 2, 13, 25, 93, 265, 325
55 Tenofovir disoproxil 4件: Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA1件: D01982 --2件: 93, 265
56 Tesamorelin 2件: GHRH; Tesamorelin1件: D06655 1件: GHRHR 💬2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 78, 265
57 Testosterone 1件: Testosterone6件: D00075 ,
D00957 ,
D00958 ,
D00959 ,
D06085 ,
D06087
1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265
58 Thiamine 2件: THIAMINE; Vitamin B11件: D08580 --5件: 8, 13, 93, 145, 265
59 Tipranavir 1件: Tipranavir2件: D03843 ,
D08605
--1件: 265
60 Volanesorsen 1件: Volanesorsen1件: D11648 1件: APOC3 💬2件: Cholesterol metabolism, PPAR signaling pathway 💬1件: 265
61 Zidovudine 3件: COMBIVIR; Retrovir; Zidovudine1件: D00413 --7件: 25, 26, 94, 135, 265, 325, 331