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 Drug(薬物リスト) ALL | DrugBank 

   e.g. "Sirolimus", "アダリムマブ"    Synonyms (Drugs) were also searched for.

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62 / 1,666 drugs found* Show info (disease name, etc.) on mouse-over.
 No.   DrugBank   薬物名(臨床試験情報から抽出)   KEGG DRUG  KEGG GENES  KEGG PATHWAY   指定難病告示番号
 1   Acyclovir  1件: Acyclovir;   D00222   -   -   5件:
13,
28,
46,
53,
60
 2   Amifostine  2件: Amifostine; Amifostine trihydrate;   D00226   -   -   1件:
28
 3   Amiodarone  3件: Amiodarone; Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhithmias); Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhythmias) plus egcg;   D00636
 D02910 
 7件: ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ8, KCNQ1, SCN5A   6件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   2件:
28,
127
 4   Aprotinin  1件: Aprotinin;   D02971   -   -   1件:
28
 5   Bendamustine  3件: Bendamustine; Bendamustine hydrochloride; Bendamustine, rituximab;   D07085
 D07501 
 -   -   2件:
28,
61
 6   Benzyl alcohol  0件:   D00077   -   -   3件:
28,
46,
271
 7   Bortezomib  6件: Bortezomib; Bortezomib/dexamethasone (bd), followed by autologous stc & maintenance bortezomib/dexamethasone; Cyclophosphamide, bortezomib, dexamethasone; Cyclophosphamide, bortezomib, dexamethasone plus daratumumab; Combination of a single dose anti-cd20 antibody and bortezomib; Bortezomib (velcade®);   D03150   1件: PSMB5   1件: Proteasome   13件:
11,
26,
28,
46,
49,
51,
61,
63,
66,
228,
256,
288,
331
 8   Busulfan  13件: Busulfan; Busulfan, cyclophosphamide, antithymocyte globulin; Busulfan, cyclophosphamide, atg; Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.; Busulfan/fludarabine phosphate/tacrolimus/methotrexate/g-csf; Fludarabine/busulfan; Busulfan iv; Busulfan, cyclophosphamide, atg, gcsf; Busulfan, fludarabine and atg; Busulfan, fludarabine, atg, tli; Fludarabine, busulfan, thymoglobulin; Busulfan, cyclophosphamide, thymoglobulin, fludarabine (conditioning regimen); Campath, busulfan, clofarabine;   D00248   -   -   13件:
19,
20,
28,
36,
49,
51,
60,
65,
164,
274,
284,
285,
326
 9   Carboplatin  1件: Carboplatin;   D01363   -   -   4件:
28,
34,
60,
85
 10   Carfilzomib  1件: Carfilzomib;   D08880   1件: PSMB5   1件: Proteasome   1件:
28
 11   Carmustine  2件: Carmustine; Carmustine, etoposide, cytarabine, and melphalan (beam);   D00254   -   -   5件:
11,
13,
14,
28,
60
 12   Ciclosporin  7件: Ciclosporin; Ciclosporina; Ciclosporine; Aerolised liposomal ciclosporin a; Ciclosporin (ciclosporinium); Ciclosporin a; Ciclosporine, ciclosporina;   D00184   5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   7件: Cellular senescence, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Osteoclast differentiation, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation   44件:
11,
14,
19,
20,
26,
28,
36,
38,
39,
40,
41,
42,
45,
46,
49,
50,
53,
55,
56,
58,
60,
61,
62,
63,
64,
65,
90,
95,
97,
113,
162,
164,
222,
223,
226,
228,
234,
269,
274,
283,
284,
285,
302,
326
 13   Cisplatin  1件: Cisplatin;   D00275   -   -   1件:
28
 14   Cyclophosphamide  49件: Cyclophosphamide; Cyclophosphamide (drug); Cyclophosphamide and atg; Cyclophosphamide monohydrate; Cyclophosphamide/glatiramer acetate; Busulfan, cyclophosphamide, antithymocyte globulin; Busulfan, cyclophosphamide, atg; Cyclophosphamide, bortezomib, dexamethasone; Cyclophosphamide, bortezomib, dexamethasone plus daratumumab; Lenalidomide, dexamethasone and cyclophosphamide; Rituximab and cyclophosphamide iv; Prednisone, cyclophosphamide; Cyclophosphamide, azathioprine,prednisone,methylprednisolone; Prednisone, methylprednisolone,cyclophosphamides; Cyclophosphamide-prednisone-azathioprine; Iv cyclophosphamide; Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.; Cyclophosphamide (cy); Cyclophosphamide (cy) (plan 1); Cyclophosphamide (cy) (plan 2); Cyclophosphamide 100mg; Cyclophosphamide 150mg; Cyclophosphamide 50mg; Cyclophosphamide, fludarabine , thymoglobulin; Cyclophosphamide, fludarabine, rabbit atg; Cyclophosphamide, fludarabine, thymoglobulin; Cyclophosphamide,campath ih and tbi; Cyclophosphamide,cyclosporine a; Fludarabine, cyclophosphamide; Haploidentical hsct using tbi free regimen, ''atg'' with ''post transplant cyclophosphamide''; Busulfan, cyclophosphamide, atg, gcsf; Campath, fludarabine, cyclophosphamide; Cyclophosphamide 30; Cyclophosphamide 40; Cyclophosphamide dose level 1; Cyclophosphamide dose level 2; Cyclophosphamide dose level 3; Cyclophosphamide dose level 4; Cyclophosphamide post transplant; Prednisone and cyclophosphamide; Prednisone plus cyclophosphamide; High-dose cyclophosphamide; Cyclophosphamide 50mg oral tablet; Cyclophosphamide and steroids; Cyclophosphamide(ctx); Cyclophosphamide + pred; Cyclophosphamide, fludarabine; Busulfan, cyclophosphamide, thymoglobulin, fludarabine (conditioning regimen); Thalidomide, cyclophosphamide and prednisone;   D00287
 D07760 
 -   -   43件:
13,
14,
16,
19,
20,
26,
28,
35,
36,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
52,
56,
60,
61,
62,
65,
66,
84,
85,
93,
96,
162,
164,
172,
222,
224,
265,
274,
283,
284,
285,
288,
326,
331
 15   Daratumumab  3件: Cyclophosphamide, bortezomib, dexamethasone plus daratumumab; Daratumumab; Daratumumab co-formulated with recombinant human hyaluronidase (rhuph20);   D10777   -   -   2件:
28,
222
 16   Dexamethasone  35件: Dexamethasone; Dexamethasone soduim phosphate; Lenalidomide and dexamethasone; Lenalidomide+dexamethasone; Lenalidomide, dexamethasone; Bortezomib/dexamethasone (bd), followed by autologous stc & maintenance bortezomib/dexamethasone; Cyclophosphamide, bortezomib, dexamethasone; Cyclophosphamide, bortezomib, dexamethasone plus daratumumab; Dexamethasone, 40 mg; Lenalidomide, dexamethasone and cyclophosphamide; Melphalan, thalidomide and dexamethasone; Pomalidomide and dexamethasone; Combination of protein a immunoadsorption, rituximab, dexamethasone plus azathioprine; Dexamethasone (50mg 1dd6, 3 consecutive days/month); Control intervention (no dexamethasone); Intraarticular dexamethasone; Intravenous dexamethasone 1 mg; Peri-neural dexamethasone 1 mg; Dexamethasone parotid irrigation; Dexamethasone (1 cycle); Dexamethasone (4 cycles); Dexamethasone abcur; Dexamethasone and rituximab; High dose dexamethasone pulses; Dexamethasone sodium phosphate; Dexamethasone sodium phosphate ph. eur.; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Dexamethasone 0.5mg tablet; Dexamethasone 2mg tablets; Dexamethasone 0,5mg; Bupivacaine/epinephrine/dexamethasone; Dexamethasone sodium phosphate 250 mg/ 10 ml; Dexamethasone 21-phosphate; Mmf and dexamethasone; Dexamethasone sodium phosphate 250 mg/10 ml solution;   D00292
 D00975
 D01510
 D01615
 D01632
 D01948
 D02174
 D02591
 D02592 
 1件: NR3C1   1件: Neuroactive ligand-receptor interaction   20件:
13,
16,
28,
35,
46,
53,
63,
65,
70,
74,
75,
81,
83,
84,
90,
96,
97,
222,
296,
299
 17   Dezamizumab  1件: Dezamizumab;   D11471   -   -   1件:
28
 18   Diflunisal  1件: Diflunisal;   D00130   1件: PTGS2   1件: Arachidonic acid metabolism   1件:
28
 19   Doxorubicin  4件: Doxorubicin; Doxorubicin hydrochloride; 4'-iodo-4'-deoxydoxorubicin; Liposomal doxorubicin;   D03899   -   -   6件:
26,
28,
34,
61,
63,
331
 20   Doxycycline  7件: Doxycycline; Interferon beta 1a, oral doxycycline; Doxycycline hyclate; Antimicrobial therapy: co-trimoxazole or doxycycline; Doxycycline 100 mg capsules; Treatment with systemic therapy (doxycycline); Doxycycline hyclate ph.eur;   D00307
 D02129
 D03903
 D03904
 D07876 
 -   -   15件:
13,
23,
28,
46,
84,
85,
89,
96,
97,
158,
162,
167,
227,
280,
299
 21   Elotuzumab  1件: Elotuzumab;   D09337   -   -   1件:
28
 22   Epigallocatechin  5件: Coconut oil and epigallocatechin gallate; Epigallocatechin; Epigallocatechin gallate; Epigallocatechin-3-gallate (egcg); Epigallocatechin-gallate;   -   -   -   4件:
13,
28,
85,
113
 23   Epigallocatechin gallate  2件: Coconut oil and epigallocatechin gallate; Epigallocatechin gallate;   -   -   -   8件:
6,
13,
17,
28,
85,
113,
206,
299
 24   Etanercept  39件: Etanercept; Enbrel (etanercept); Etanercept 50 mg solution for injection; 50 mg etanercept; Anti-tnf therapy (etanercept or adalimumab); Bdmard withdrawal (etanercept, adalimumab, infliximab, certolizumab, golimumab, tozilizumab, abatacept); Commercial formulation etanercept; Etanercept (enbrel); Etanercept (enbreltm); Etanercept + methotrexate; Etanercept , methotrexate; Etanercept / autoinjector a; Etanercept 50mg; Etanercept biosimilar; Etanercept liquid; Etanercept or adalimumab; Etanercept pre-filled syringe sq injection; Etanercept treatment; Etanercept via autoinjector a; Etanercept via autoinjector b; Etanercept, other biologics, disease-modifying antirheumatic drugs (dmards), etc; Infliximab, etanercept; Infliximab, etanercept, adalimumab; Methotrexate - etanercept - prednisolone arm; New formulation etanercept; Phase 1: etanercept; Reumatocept (etanercept); Sb4 (etanercept biosimilar); Sb4 (proposed biosimilar to etanercept); Tnf blockers (infliximab, adalimumab, etanercept); Tumor necrosis factor inhibitor (etanercept, infliximab, adalimumab, and golimumab); Etanercept, methotrexate, prednisolone; Adalimumab, etanercept, golimumab or infliximab; Etanercept (50mg per week); Etanercept (50mg per week, for 2 weeks); Etanercept (50mg per week, for 4 weeks); Etanercept (full-dose); Etanercept (half-dose); Tapering or discontinuation of etanercept;   D00742   2件: LTA, TNF   9件: Adipocytokine signaling pathway, Antigen processing and presentation, Apoptosis, Cytokine-cytokine receptor interaction, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Rheumatoid arthritis, TGF-beta signaling pathway   15件:
15,
28,
35,
38,
39,
46,
50,
53,
56,
60,
85,
228,
271,
285,
298
 25   Etoposide  2件: Etoposide; Carmustine, etoposide, cytarabine, and melphalan (beam);   D00125
 D04107 
 -   -   11件:
11,
13,
14,
26,
28,
34,
60,
65,
85,
164,
331
 26   Filgrastim  7件: Filgrastim; Pegfilgrastim; Ep2006 (filgrastim); Filgrastim hexal; Filgrastim, alemtuzumab; Granulocyte colony-stimulating factor (filgrastim); Filgrastim (g-csf);   D03235   1件: CSF3R   5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   28件:
2,
6,
13,
16,
25,
26,
28,
34,
35,
36,
40,
41,
42,
45,
46,
49,
51,
60,
62,
65,
85,
96,
113,
164,
283,
284,
285,
331
 27   Fludarabine  23件: Fludarabine; Fludarabine phosphate; Fludarabine monophosphate; Sq fludarabine; Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.; Busulfan/fludarabine phosphate/tacrolimus/methotrexate/g-csf; Cyclophosphamide, fludarabine , thymoglobulin; Cyclophosphamide, fludarabine, rabbit atg; Cyclophosphamide, fludarabine, thymoglobulin; Fludarabine (flu); Fludarabine, cyclophosphamide; Fludarabine/ melphalan; Fludarabine/busulfan; Busulfan, fludarabine and atg; Busulfan, fludarabine, atg, tli; Campath, fludarabine, cyclophosphamide; Fludarabine phosphate 30 mg; Fludarabine phosphate 40 mg; Fludarabine, busulfan, thymoglobulin; Fludarabine, melphalan, thiotepa; Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan; Cyclophosphamide, fludarabine; Busulfan, cyclophosphamide, thymoglobulin, fludarabine (conditioning regimen);   D01907
 D07966 
 1件: RRM1   2件: Purine metabolism, Pyrimidine metabolism   17件:
13,
28,
36,
46,
49,
51,
60,
61,
62,
65,
85,
96,
164,
283,
284,
285,
326
 28   Foscarnet  2件: Foscarnet; Foscarnet sodium;   D00579
 D02267 
 -   -   2件:
28,
60
 29   Fx-1006A  1件: Fx-1006a;   -   -   -   1件:
28
 30   Ganciclovir  2件: Ganciclovir; Valganciclovir;   D00333
 D04301 
 -   -   3件:
28,
60,
97
 31   Green tea leaf  1件: Green tea leaf;   D06903   -   -   5件:
6,
17,
28,
46,
96
 32   Hyaluronidase  7件: Daratumumab co-formulated with recombinant human hyaluronidase (rhuph20); Hyaluronidase; Recombinant human hyaluronidase; Recombinant human hyaluronidase (rhuph20); Recombinant human hyaluronidase (rhuph20)+ immune globulin intravenous (igiv); Recombinant human hyaluronidase + immune globulin intravenous; Rituximab or rituximab hyaluronidase human;   D04455
 D04456
 D06604 
 -   -   3件:
28,
65,
331
 33   Ibrutinib  1件: Ibrutinib;   D10223   1件: BTK   1件: B cell receptor signaling pathway   2件:
28,
61
 34   Imatinib  6件: Imatinib; Imatinib mesilate; Imatinib mesylate; Imatinib mesylate (gleevec); Bevacizumab (avastin) and imatinib mesylate (gleevec); Imatinib mesylate 400mg capsule;   D01441
 D08066 
 3件: ABL1, KIT, PDGFRA   3件: Chronic myeloid leukemia, MAPK signaling pathway, Pathways in cancer   11件:
13,
28,
34,
35,
46,
51,
85,
86,
87,
89,
162
 35   Indium  5件: Indium; Indium 111-radiolabelled anti-cd66; Indium­ 111 ­labelled anti­-cd66; Indium-111 pentreotide; Indium-dtpa;   -   -   -   3件:
28,
84,
299
 36   Inotersen  1件: Inotersen;   D10940   -   -   1件:
28
 37   Interferon alfa  5件: Interferon alfa; Interferon alfa-2b; Recombinant interferon alfa; Interferon alfa-2a; Pegylated interferon alfa;   D03305   2件: IFNAR1, IFNAR2   8件: Cytokine-cytokine receptor interaction, Hepatitis B, Hepatitis C, JAK-STAT signaling pathway, Measles, Natural killer cell mediated cytotoxicity, Pathways in cancer, Toll-like receptor signaling pathway   5件:
25,
26,
28,
56,
96
 38   Iodine  1件: Iodine;   D00108   -   -   3件:
28,
46,
88
 39   Isatuximab  1件: Isatuximab;   D11050   -   -   1件:
28
 40   Ixazomib  3件: Ixazomib; Ixazomib (ninlaro®) capsules; Ixazomib citrate;   D10130   1件: PSMB5   1件: Proteasome   4件:
13,
16,
28,
61
 41   Lenalidomide  5件: Lenalidomide; Lenalidomide and dexamethasone; Lenalidomide+dexamethasone; Lenalidomide, dexamethasone; Lenalidomide, dexamethasone and cyclophosphamide;   D04687   1件: TNF   6件: Apoptosis, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, TNF signaling pathway   8件:
16,
26,
28,
34,
49,
96,
284,
300
 42   Melphalan  8件: Melphalan; Carmustine, etoposide, cytarabine, and melphalan (beam); Melphalan, thalidomide and dexamethasone; Propylene glycol-free melphalan hydrochloride; Fludarabine/ melphalan; Melphalan hydrochloride; Fludarabine, melphalan, thiotepa; Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan;   D00369   -   -   14件:
11,
13,
14,
19,
20,
28,
60,
62,
65,
96,
164,
234,
284,
285
 43   Miridesap  1件: Miridesap;   D11464   -   -   1件:
28
 44   Mycophenolate mofetil  17件: Mycophenolate mofetil; Mycophenolate mofetil (cellcept); Mycophenolate mofetil [cellcept]; Mycophenolate mofetil (mmf) 3 g/day; Mycophenolate mofetil 2 g/day; Cellcept (mycophenolate mofetil); Mycophenolate mofetil,methotrexate; Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate); Mycophenolate mofetil (mmf); Mycophenolate mofetil plus lower dose of prednisone; Azathioprine or mycophenolate mofetil; Mycophenolate mofetil orally 1000 mg twice a day (bid); Mycophenolate mofetil, low dose steroid; Prednisolone and mycophenolate mofetil; Mycophenolate mofetil(mmf); Cyclosporine combine with mycophenolate mofetil; Prednisone and mycophenolate mofetil;   D00752
 D05094
 D05095 
 2件: IMPDH1, IMPDH2   1件: Purine metabolism   32件:
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300
 45   Mycophenolic acid  2件: Mycophenolic acid; Mycophenolic acid mofetil;   D05096   2件: IMPDH1, IMPDH2   1件: Purine metabolism   34件:
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
84,
85,
95,
96,
162,
164,
222,
224,
226,
228,
234,
283,
284,
285,
300
 46   Pentetic acid  0件:   D05422   -   -   3件:
13,
28,
299
 47   Phosphate ion  0件:   -   -   -   29件:
2,
3,
11,
12,
13,
28,
36,
46,
49,
51,
53,
60,
62,
65,
70,
78,
81,
83,
90,
96,
97,
164,
235,
256,
283,
284,
285,
286,
299
 48   Pomalidomide  4件: Pomalidomide; Pomalidomide and dexamethasone; Pomalidomide (cc-4047; Pomalidomide oral product;   D08976   2件: IL6, TNF   6件: Apoptosis, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, TNF signaling pathway   6件:
28,
34,
51,
85,
227,
331
 49   Propylene glycol  2件: Propylene glycol; Propylene glycol-free melphalan hydrochloride;   D00078   -   -   1件:
28
 50   Sargramostim  3件: Sargramostim; Sargramostim (leukine); Gm-csf (granulocyte-macrophage colony-stimulating factor, sargramostim);   D05803   1件: CSF2RA   4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer   6件:
6,
28,
60,
62,
96,
229
 51   Siltuximab  1件: Siltuximab;   D09669   1件: IL6   2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway   2件:
28,
331
 52   Sorbitol  2件: D-sorbitol; Sorbitol;   D00096   -   -   3件:
10,
28,
299
 53   Sunitinib  3件: Sunitinib; Sunitinib malate; Sutent®/sunitinib;   D06402
 D08552 
 9件: CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB, RET   3件: MAPK signaling pathway, Pathways in cancer, VEGF signaling pathway   2件:
28,
34
 54   Tafamidis  2件: Tafamidis; Tafamidis meglumine;   D09673   1件: TTR   1件: Thyroid hormone synthesis   1件:
28
 55   Thalidomide  9件: Thalidomide; Thalidomide (drug); Fpf 300 (thalidomide); Melphalan, thalidomide and dexamethasone; Thalidomide pharmion; Thalidomide celgene - 50 mg capsula rigida - uso orale - blister (pvc/pe/aclar/alu) 28 capsule; Thalidomide 100mg; Thalidomide 150mg; Thalidomide, cyclophosphamide and prednisone;   D00754   1件: TNF   4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, NF-kappa B signaling pathway, TNF signaling pathway   18件:
2,
16,
20,
28,
49,
51,
53,
65,
84,
85,
94,
96,
97,
227,
271,
280,
298,
331
 56   Thiotepa  5件: Thiotepa; Thiotepa--escalated dose; Thiotepa--single daily dose; Fludarabine, melphalan, thiotepa; Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan;   D00583   -   -   11件:
13,
19,
20,
28,
51,
60,
65,
85,
96,
164,
284
 57   Tolcapone  1件: Tolcapone;   D00786   1件: COMT   1件: Dopaminergic synapse   3件:
6,
28,
127
 58   Valganciclovir  3件: Valganciclovir; Valganciclovir [valcyte]; Valganciclovir (vgc);   D02495   -   -   6件:
28,
60,
85,
97,
299,
331
 59   Venetoclax  1件: Venetoclax;   D10679   1件: BCL2   2件: Apoptosis, Pathways in cancer   1件:
28
 60   Vorhyaluronidase alfa  0件:   D06604   -   -   3件:
14,
28,
65
 61   Water  13件: 5% glucose water solution; Water; Pseudoephedrine + 480 ml water; Pseudoephedrine + 50 ml water; 15 o water; Water for injection; 15-o labeled water; Pl 12185/0002 & pl 12185/0005(water for injection); Dextrose, 5% in water; High water intake; Lactose in water; Water for injections; Water for injections, ep;   D00001   -   -   22件:
2,
5,
6,
13,
17,
19,
28,
35,
46,
53,
57,
63,
65,
67,
78,
84,
97,
193,
226,
271,
278,
299
 62   Yttrium Y-90  0件:   -   -   -   1件:
28

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