Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acarbose 1件: Acarbose1件: Acarbose 💬5件: AMY2A,
AMY2B,
GAA,
GANC,
MGAM 💬
7件: Carbohydrate digestion and absorption, Galactose metabolism, Lysosome, Metabolic pathways, Pancreatic secretion, Salivary secretion, Starch and sucrose metabolism 💬1件: 298 💬
2 Acetate 1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
3 Acetylcarnitine 2件: Acetyl-L-carnitine; Acetylcarnitine---3件: 2, 265, 298 💬
4 Acetylcysteine 3件: ACETYLCYSTEINE; Mucomyst; N-acetylcysteine1件: Acetylcysteine 💬--21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
5 Alanine 2件: Alanine; L-alanine1件: Alanine 💬--4件: 6, 13, 298, 299 💬
6 Alpha-1-proteinase inhibitor 5件: Alpha 1-Proteinase Inhibitor; ALPHA-1-ANTITRYPSIN; Alpha1-proteinase Inhibitor; Glassia; Prolastin-C---3件: 231, 298, 299 💬
7 Amino acids 1件: Amino acids---3件: 70, 240, 298 💬
8 Amlodipine 1件: Amlodipine1件: Amlodipine 💬4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬
37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 13, 51, 67, 298 💬
9 Ascorbic acid 4件: Acidum ascorbicum; Ascorbic Acid; Iron; Vitamin C1件: Ascorbic acid 💬--8件: 10, 97, 192, 206, 210, 211, 212, 298 💬
10 Bentiromide 0件: 1件: Bentiromide 💬--3件: 51, 117, 298 💬
11 Bupivacaine 2件: Bupivacaine; BUPIVACAINE HYDROCHLORIDE1件: Bupivacaine 💬5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
12 Calcium 2件: Calcio; Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
13 Cholecalciferol 5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D31件: Cholecalciferol 💬1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬24件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
14 Diazepam 1件: Diazepam1件: Diazepam 💬16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 46, 155, 298 💬
15 Dronabinol 4件: Delta-9-tetrahydrocannabinol; DRONABINOL; Sativex; Tetrahydrocannabinol1件: Dronabinol 💬2件: CNR1,
CNR2 💬
4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬8件: 2, 8, 13, 36, 46, 96, 271, 298 💬
16 Esomeprazole 3件: Esomeprazole; Nexium; Omeprazole1件: Esomeprazole 💬2件: ATP4A,
ATP4B 💬
4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299 💬
17 Ethanol 3件: Alcohol; Ethanol; PREDNISONE1件: Ethanol 💬--5件: 58, 97, 279, 280, 298 💬
18 Gabapentin 4件: Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN1件: Gabapentin 💬5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬
9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298 💬
19 Gold 1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬
20 Hydroxychloroquine 3件: Hydroxychloroquine; Hydroxychloroquine sulfate; PLAQUENIL1件: Hydroxychloroquine 💬--27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
21 Indomethacin 2件: INDOMETACIN; Indomethacin1件: Indomethacin 💬2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 225, 271, 298 💬
22 Lacosamide 1件: Lacosamide1件: Lacosamide 💬2件: SCN3A,
SCN9A 💬
1件: Taste transduction 💬4件: 2, 46, 149, 298 💬
23 Lanreotide 3件: Lanreotide; LANREOTIDE ACETATE; Somatuline Autogel---4件: 67, 73, 85, 298 💬
24 Levocarnitine 4件: Carnitine; L-Carnitine; Levocarnitine; Xyzal1件: Levocarnitine 💬--11件: 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316 💬
25 Magnesium 1件: Magnesium---19件: 6, 11, 13, 46, 51, 63, 64, 70, 93, 97, 111, 166, 225, 235, 284, 291, 296, 297, 298 💬
26 Magnesium aspartate 1件: Magnesium aspartate1件: Magnesium L-aspartate 💬--1件: 298 💬
27 Magnesium aspartate hydrochloride 1件: MAGNESIUM ASPARTATE HYDROCHLORIDE---1件: 298 💬
28 Methionine 3件: Butanoic acid; L-methionine; Methionine1件: Methionine 💬--6件: 34, 84, 93, 229, 298, 300 💬
29 Midazolam 2件: Midazolam; Midazolam injection1件: Midazolam 💬16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
30 MS-1819 1件: MS1819-SD---2件: 298, 299 💬
31 Omeprazole 4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM1件: Omeprazole 💬2件: ATP4A,
ATP4B 💬
4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
32 Oxycodone 2件: OXYCODONE; OXYCODONE HYDROCHLORIDE1件: Oxycodone 💬3件: OPRD1,
OPRK1,
OPRM1 💬
5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 13, 70, 226, 298 💬
33 Pancrelipase 2件: Pancreatin; Pancrelipase1件: Pancrelipase 💬--2件: 298, 299 💬
34 Paricalcitol 1件: Paricalcitol1件: Paricalcitol 💬1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬5件: 19, 66, 218, 238, 298 💬
35 Pentoxifylline 1件: Pentoxifylline1件: Pentoxifylline 💬--12件: 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298 💬
36 Perflubutane 1件: Perflubutane1件: Perflubutane 💬--2件: 298, 300 💬
37 Pioglitazone 1件: Pioglitazone1件: Pioglitazone 💬1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
38 Pregabalin 2件: Lyrica; Pregabalin1件: Pregabalin 💬4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬
7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬5件: 13, 36, 46, 70, 298 💬
39 Proglumide 1件: Proglumide1件: Proglumide 💬1件: CCKBR 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬1件: 298 💬
40 Reparixin 1件: Reparixin1件: Reparixin 💬2件: CXCR1,
CXCR2 💬
7件: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Human cytomegalovirus infection, Phospholipase D signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬2件: 298, 299 💬
41 Secretin human 3件: Human Secretin; Secretin; Synthetic human secretin---1件: 298 💬
42 Selenium 1件: Selenium---4件: 13, 96, 278, 298 💬
43 Simvastatin 3件: SIMVASTATIN; Simvastatina; Simvastatine1件: Simvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
44 Sulfanilamide 0件: 1件: Sulfanilamide 💬--4件: 6, 30, 60, 298 💬
45 Tanezumab 1件: Tanezumab1件: Tanezumab 💬1件: NGF 💬9件: Apoptosis, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬2件: 226, 298 💬
46 Thalidomide 1件: Thalidomide1件: Thalidomide 💬1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
47 Tocopherol 2件: Tocoferol; Tocopherol1件: Tocopherol 💬--6件: 13, 49, 90, 206, 257, 298 💬
48 Triamcinolone 4件: Kenalog; Naltrexone; TRIAMCINOLONE; TRIAMCINOLONE ACETONIDE1件: Triamcinolone 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
49 Trimethoprim 2件: Bactrim; Trimethoprim1件: Trimethoprim 💬--8件: 36, 44, 49, 60, 61, 85, 298, 299 💬
50 Tyrosine 4件: Alanine; L-tyrosine; Propanoic acid; Tyrosine1件: Tyrosine 💬--5件: 6, 75, 86, 111, 298 💬
51 Vitamin D 3件: Calciferol; Cod liver oil; Vitamin D---20件: 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299 💬