Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetylcysteine 3件: Acetylcysteine; Mucomyst; N-acetylcysteine1件: Acetylcysteine 💬--21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
2 Alemtuzumab 4件: Alemtuzumab; Campath; Lemtrada; MABCAMPATH1件: Alemtuzumab 💬1件: CD52 💬-22件: 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬
3 Aminophylline 1件: Aminophylline1件: Aminophylline 💬18件: ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬
23件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 63 💬
4 Amoxicillin 4件: Amoxicilina; Amoxicillin; Amoxycillin; Augmentin2件: Amoxicillin ,
Amoxicillin 💬
--9件: 6, 19, 46, 63, 84, 96, 97, 222, 299 💬
5 Atorvastatin 3件: Atorvastatin; Atorvastatin calcium; Lipitor1件: Atorvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
6 Avatrombopag 2件: Avatrombopag; Doptelet1件: Avatrombopag 💬1件: MPL 💬2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬2件: 60, 63 💬
7 Azathioprine 3件: Azathioprine; Azatioprina; Imuran1件: Azathioprine 💬--21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
8 Belimumab 2件: BELIMUMAB; BENLYSTA1件: Belimumab 💬1件: TNFSF13B 💬4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬
9 Bevifimod 1件: STAPHYLOCOCCAL PROTEIN A---1件: 63 💬
10 Blisibimod 1件: Blisibimod1件: Blisibimod 💬--5件: 43, 44, 49, 63, 66 💬
11 Bortezomib 3件: Bortezomib; Bortezomib Accord; VELCADE1件: Bortezomib 💬1件: PSMB5 💬8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
12 Clarithromycin 1件: CLARITHROMYCIN1件: Clarithromycin 💬--8件: 6, 63, 84, 96, 97, 222, 228, 299 💬
13 Cyclosporine 10件: CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis1件: Cyclosporine 💬5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
14 Danazol 1件: Danazol1件: Danazol 💬3件: AR,
ESR1,
PGR 💬
12件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬5件: 60, 63, 64, 65, 285 💬
15 Daratumumab 2件: Daratumumab; Darzalex1件: Daratumumab 💬1件: CD38 💬7件: Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬5件: 13, 28, 48, 49, 63 💬
16 Decitabine 1件: Decitabine1件: Decitabine 💬3件: DNMT1,
DNMT3A,
DNMT3B 💬
3件: Cysteine and methionine metabolism, Metabolic pathways, MicroRNAs in cancer 💬3件: 13, 60, 63 💬
17 Dexamethasone 5件: Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex1件: Dexamethasone 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
18 Diacerein 1件: DIACEREIN1件: Diacerein 💬--3件: 36, 46, 63 💬
19 Efgartigimod alfa 1件: EFGARTIGIMOD ALFA1件: Efgartigimod alfa 💬1件: FCGRT 💬-6件: 11, 14, 35, 53, 63, 162 💬
20 Eltrombopag 3件: Eltrombopag; Promacta; REVOLADE---5件: 60, 63, 65, 284, 285 💬
21 GMA-161 0件: ---1件: 63 💬
22 Gold 1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬
23 Hetrombopag 1件: Hetrombopag---2件: 60, 63 💬
24 Human immunoglobulin G 19件: Bivigam; CUTAQUIG; CUVITRU; GAMMAGARD LIQUID; Gammaplex; GAMUNEX-C; Hizentra; Human immunoglobulin G; Human normal immunoglobulin; HYQVIA; Immune globulin; Immunoglobulin; IMMUNOGLOBULIN G; IVIG; KIOVIG; OCTAGAM; PANZYGA; Privigen; Vivaglobin---10件: 11, 13, 14, 17, 43, 45, 50, 51, 63, 65 💬
25 Human interleukin-2 3件: Human interleukin-2; IL-2; INTERLEUKIN-2---18件: 2, 13, 35, 46, 49, 50, 51, 53, 55, 56, 60, 63, 65, 95, 96, 97, 162, 271 💬
26 Hydroxychloroquine 3件: Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE; Plaquenil1件: Hydroxychloroquine 💬--27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
27 Ianalumab 1件: Ianalumab1件: Ianalumab 💬1件: TNFRSF13C 💬5件: Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬7件: 35, 46, 49, 53, 61, 63, 95 💬
28 Lansoprazole 1件: Lansoprazole1件: Lansoprazole 💬2件: ATP4A,
ATP4B 💬
4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299 💬
29 Magnesium 1件: Magnesium---19件: 6, 11, 13, 46, 51, 63, 64, 70, 93, 97, 111, 166, 225, 235, 284, 291, 296, 297, 298 💬
30 Methylprednisolone 4件: Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: Methylprednisolone 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
31 Metronidazole 3件: Flagyl; Metronidazol; Metronidazole1件: Metronidazole 💬--7件: 46, 51, 63, 94, 96, 97, 291 💬
32 Mezagitamab 1件: Mezagitamab1件: Mezagitamab 💬1件: CD38 💬7件: Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬2件: 63, 66 💬
33 Montelukast 3件: Montelukast; MONTELUKAST SODIUM; Singulair1件: Montelukast 💬1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬8件: 6, 13, 46, 61, 63, 85, 98, 228 💬
34 Natalizumab 2件: Natalizumab; Tysabri1件: Natalizumab 💬1件: ITGA4 💬14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬6件: 13, 15, 25, 46, 63, 96 💬
35 Orelabrutinib 1件: Orelabrutinib1件: Orelabrutinib 💬1件: BTK 💬7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬4件: 13, 49, 61, 63 💬
36 Palmitic Acid 1件: Palmitate1件: Palmitic acid 💬--1件: 63 💬
37 Prednisolone 3件: Prednisolona; Prednisolone; Prednisolonum1件: Prednisolone 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
38 Prednisone 3件: PREDNISONA; Prednisone; RAYOS1件: Prednisone 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
39 Pyrimethamine 2件: Daraprim; PYRIMETHAMINE1件: Pyrimethamine 💬--12件: 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265 💬
40 Recombinant Human Thrombopoietin 2件: Recombinant Human Thrombopoietin; RhTPO---2件: 60, 63 💬
41 Rituximab 6件: MabThera; Rituxan; Rituximab; Rixathon; Ruxience; TRUXIMA1件: Rituximab 💬1件: MS4A1 💬1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
42 Romiplostim 2件: NPLATE; ROMIPLOSTIM1件: Romiplostim 💬1件: MPL 💬2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬4件: 60, 63, 64, 65 💬
43 Rozanolixizumab 1件: ROZANOLIXIZUMAB1件: Rozanolixizumab 💬1件: FCGRT 💬-3件: 11, 14, 63 💬
44 Sirolimus 3件: RAPAMUNE; Rapamycin; Sirolimus1件: Sirolimus 💬1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
45 Thrombopoietin 1件: Thrombopoietin---3件: 47, 60, 63 💬
46 Toralizumab 1件: Anti-CD40L1件: Toralizumab 💬1件: CD40LG 💬14件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬1件: 63 💬
47 Tretinoin 5件: ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID1件: Tretinoin 💬3件: PML,
RARA,
RARB 💬
12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231 💬
48 Vonoprazan 1件: Vonoprazan1件: Vonoprazan 💬2件: ATP4A,
ATP4B 💬
4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 63, 98 💬
49 Water 8件: AVONEX; ENBREL; Hiberix; INDOCYANINE GREEN; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION1件: Water 💬--21件: 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
50 Zanubrutinib 1件: Zanubrutinib1件: Zanubrutinib 💬1件: BTK 💬7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬5件: 13, 63, 222, 300, 331 💬